nuclear receptor subfamily 1, group I, member 2

Synonym

PXR, Pregnane X receptor, PAR, NR1I2, PRR, Steroid and xenobiotic receptor, PARq, nuclear receptor subfamily 1, group I, member 2, SAR, ONR1, Orphan nuclear receptor PAR1, Orphan nuclear receptor PXR, BXR, SXR

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

nodata

GeneChip

cerebrum:4.45

cerebellum:4.48

brain stem:4.49

corpus callosum/glia:4.37

pineal gland:-

peripheral nerve:4.36

spine:4.45

retina:-

eye:-

artery/aorta:4.97

vein:4.53

lymphnode:4.37

peripheral blood:-

spleen:4.31

thymus:4.27

bone marrow:4.61

adipose:4.44

bone:-

skin:4.31

CAGE

cerebrum:0

cerebellum:-

brain stem:0

corpus callosum/glia:0

pineal gland:0

peripheral nerve:-

spine:0

retina:-

eye:-

artery/aorta:0

vein:0

lymphnode:0

peripheral blood:-

spleen:0

thymus:0

bone marrow:-

adipose:0.14

bone:-

skin:-

RNA-seq

cerebrum:0.00

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:0

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:0

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

nodata

GeneChip

uterus:4.26

placenta:4.37

prostate:4.17

ovary:4.35

testis:4.27

heart:4.46

muscle:4.55

esophagus:4.28

stomach:4.33

intestine:5.83

colon:5.85

liver/hepato:9.18

lung:4.40

bladder:-

kidney:4.30

pituitary:4.55

thyroid/parathyroid:4.41

adrenal gland:4.25

pancreas:4.67

breast:4.21

salivary:4.32

CAGE

uterus:0

placenta:0

prostate:0

ovary:0

testis:0

heart:0

muscle:0

esophagus:0

stomach:-

intestine:4.14

colon:3.34

liver/hepato:2.62

lung:0.05

bladder:0

kidney:0

pituitary:0

thyroid/parathyroid:0

adrenal gland:-

pancreas:0

breast:0

salivary:0

RNA-seq

uterus:-

placenta:-

prostate:0.06

ovary:0.00

testis:0.01

heart:0.00

muscle:0

esophagus:-

stomach:-

intestine:-

colon:0.06

liver/hepato:1.97

lung:0

bladder:-

kidney:0.00

pituitary:-

thyroid/parathyroid:0.00

adrenal gland:0.00

pancreas:-

breast:0.00

salivary:-

IDs

Refseq ID	NM_033013
Gene ID	8856
Unigene ID	-
Probe set ID	207202_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000144852
GTEx ID	ENSG00000144852

Orthologous Gene

Mouse[2]	NM_010936
Rat[1]	NM_052980

Chromosomal Region

3q13.33 [119,499,331 - 119,537,332]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR001723	Steroid hormone receptor
IPR001728	Thyroid hormone receptor
IPR013088	Zinc finger, NHR/GATA-type
IPR001628	Zinc finger, nuclear hormone receptor-type

Gene Ontology (GO ID)

Biological Process

GO:0046618	drug export
GO:0042738	exogenous drug catabolic process
GO:0010467	gene expression
GO:0030522	intracellular receptor-mediated signaling pathway
GO:0045892	negative regulation of transcription, DNA-dependent
GO:0045893	positive regulation of transcription, DNA-dependent
GO:0007165	signal transduction
GO:0008202	steroid metabolic process
GO:0006367	transcription initiation from RNA polymerase II promoter
GO:0006805	xenobiotic metabolic process
GO:0042908	xenobiotic transport

Cellular Component

GO:0005654

nucleoplasm

Molecular Function

GO:0008144	drug binding
GO:0004879	ligand-dependent nuclear receptor activity
GO:0005515	protein binding
GO:0043565	sequence-specific DNA binding
GO:0003707	steroid hormone receptor activity
GO:0003713	transcription coactivator activity
GO:0008270	zinc ion binding

nuclear receptor subfamily 1, group I, member 2

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function