LIM domain binding 1

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Synonym

CLIM-2, LDB1, CLIM2, LIM domain-binding factor CLIM2, LIM domain binding 1, NLI, LIM domain-binding protein 1, Carboxyl-terminal LIM domain-binding protein 2

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:15.40 cerebellum:12.60 brain stem:- corpus callosum/glia:29.20 pineal gland:- peripheral nerve:- spine:- retina:- eye:23.50 artery/aorta:30 vein:- lymphnode:101.10 peripheral blood:- spleen:- thymus:38.70 bone marrow:118.10 adipose:- bone:12.80 skin:33.60
GeneChip cerebrum:6.77 cerebellum:6.47 brain stem:6.77 corpus callosum/glia:6.66 pineal gland:- peripheral nerve:6.66 spine:6.57 retina:- eye:- artery/aorta:6.83 vein:6.87 lymphnode:7.41 peripheral blood:- spleen:7.64 thymus:6.90 bone marrow:7.47 adipose:7.01 bone:- skin:7.47
CAGE cerebrum:4.31 cerebellum:- brain stem:4.12 corpus callosum/glia:4.38 pineal gland:4.06 peripheral nerve:- spine:3.96 retina:- eye:- artery/aorta:4.42 vein:4.24 lymphnode:4.25 peripheral blood:- spleen:3.98 thymus:4.21 bone marrow:- adipose:3.49 bone:- skin:-
RNA-seq cerebrum:0.22 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:1.27 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.24 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:45.60 placenta:10.90 prostate:11.30 ovary:- testis:34.60 heart:89.40 muscle:- esophagus:- stomach:21.20 intestine:- colon:25.40     liver/hepato:-        lung:24.40    bladder:- kidney:10.40 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:35.60 breast:37.20 salivary:-
GeneChip uterus:7.18 placenta:7.22 prostate:7.06 ovary:7.26 testis:7.04 heart:6.99 muscle:6.83 esophagus:7.46 stomach:7.16 intestine:6.87 colon:6.80 liver/hepato:6.97 lung:6.92 bladder:- kidney:7.18 pituitary:7.12 thyroid/parathyroid:7.26 adrenal gland:7.17 pancreas:6.69 breast:7.38 salivary:7.32
CAGE uterus:4.48 placenta:3.92 prostate:4.37 ovary:4.28 testis:3.96 heart:3.83 muscle:3.69 esophagus:3.96 stomach:- intestine:3.55 colon:4.00     liver/hepato:3.02    lung:3.98 bladder:4.08 kidney:3.78 pituitary:3.66 thyroid/parathyroid:3.98 adrenal gland:- pancreas:3.52 breast:3.62 salivary:4.54
RNA-seq uterus:- placenta:- prostate:1.46 ovary:1.08 testis:1.80 heart:0.11 muscle:0.00 esophagus:- stomach:- intestine:- colon:0.13     liver/hepato:0.00        lung:0.46    bladder:- kidney:0.16 pituitary:- thyroid/parathyroid:0.92 adrenal gland:0.37 pancreas:- breast:0.44 salivary:-

Gene Information

IDs

Refseq ID NM_003893
Gene ID 8861
Unigene ID Hs.454418
Probe set ID 35160_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000198728
GTEx ID ENSG00000198728

Orthologous Gene

Mouse[2]  NM_001113408, NM_010697
Rat[1]  NM_001107601, NM_010697

Chromosomal Region

10q24.32  [103,867,317  -  103,880,210]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

9209374
9214632
9315627
9391090
9452425
9503020
9736723
9799849
9872335
10083735
10640831
10767331
10866689
11751867
11882901
12153047
12239153
12381786
12477932
12642495
12727888
12792813
12874135
12925972
14743429
15164054
15231748
15489334
16189514
16314316
16385451
16407974
16713569
16815859
17437998
17910069
18583962
19117995
19497860
20211142
20423330
20447379
20603019
21139048
21988832
22010104
23000965
23812588

Gene Ontology  (GO ID)

Biological Process

GO:0009948  anterior/posterior axis specification
GO:0022607  cellular component assembly
GO:0021702  cerebellar Purkinje cell differentiation
GO:0010669  epithelial structure maintenance
GO:0001702  gastrulation with mouth forming second
GO:0001942  hair follicle development
GO:0060322  head development
GO:0043973  histone H3-K4 acetylation
GO:0007275  multicellular organismal development
GO:0045647  negative regulation of erythrocyte differentiation
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0030182  neuron differentiation
GO:0045785  positive regulation of cell adhesion
GO:0046985  positive regulation of hemoglobin biosynthetic process
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0032784  regulation of RNA elongation
GO:0006355  regulation of transcription, DNA-dependent
GO:0035019  somatic stem cell maintenance
GO:0006366  transcription from RNA polymerase II promoter
GO:0006351  transcription, DNA-dependent
GO:0000972  transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery
GO:0016055  Wnt receptor signaling pathway

Cellular Component

GO:0005911  cell-cell junction
GO:0000790  nuclear chromatin
GO:0005634  nucleus
GO:0043234  protein complex
GO:0005667  transcription factor complex

Molecular Function

GO:0003682  chromatin binding
GO:0019899  enzyme binding
GO:0030274  LIM domain binding
GO:0042803  protein homodimerization activity
GO:0043621  protein self-association
GO:0003714  transcription corepressor activity