B-cell CLL/lymphoma 10

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Synonym

B-cell lymphoma/leukemia 10, mE10, CARMEN, Cellular-E10, CLAP, CARD-like apoptotic protein, CIPER, c-E10, Mammalian CARD-containing adapter molecule E10, Cellular homolog of vCARMEN, Bcl-10, cCARMEN, hCLAP, BCL10, B-cell CLL/lymphoma 10, CARD-containing molecule enhancing NF-kappa-B

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:10.70 cerebellum:- brain stem:- corpus callosum/glia:29.20 pineal gland:- peripheral nerve:61.30 spine:- retina:- eye:- artery/aorta:179.90 vein:66.60 lymphnode:70.80 peripheral blood:18.20 spleen:18.90 thymus:- bone marrow:39.40 adipose:- bone:- skin:9.60
GeneChip cerebrum:5.23 cerebellum:5.27 brain stem:5.10 corpus callosum/glia:5.37 pineal gland:- peripheral nerve:5.54 spine:5.58 retina:- eye:- artery/aorta:6.07 vein:5.96 lymphnode:6.58 peripheral blood:- spleen:7.05 thymus:6.62 bone marrow:5.68 adipose:6.18 bone:- skin:6.54
CAGE cerebrum:2.82 cerebellum:- brain stem:2.80 corpus callosum/glia:3.01 pineal gland:2.83 peripheral nerve:- spine:3.05 retina:- eye:- artery/aorta:3.52 vein:3.57 lymphnode:4.03 peripheral blood:- spleen:3.87 thymus:3.67 bone marrow:- adipose:3.82 bone:- skin:-
RNA-seq cerebrum:1.69 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:3.29 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:2.67 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:27.30 placenta:10.90 prostate:- ovary:74.50 testis:43.30 heart:12.80 muscle:- esophagus:- stomach:21.20 intestine:32.40 colon:25.40     liver/hepato:21.10        lung:24.40    bladder:125.60 kidney:10.40 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:102.20 salivary:-
GeneChip uterus:6.77 placenta:6.18 prostate:7.03 ovary:6.67 testis:5.83 heart:5.81 muscle:5.21 esophagus:7.24 stomach:6.53 intestine:6.18 colon:7.20 liver/hepato:5.68 lung:6.88 bladder:- kidney:6.22 pituitary:5.36 thyroid/parathyroid:6.35 adrenal gland:6.04 pancreas:5.21 breast:6.60 salivary:5.88
CAGE uterus:3.75 placenta:3.37 prostate:3.52 ovary:3.38 testis:3.29 heart:3.30 muscle:2.33 esophagus:4.27 stomach:- intestine:4.21 colon:4.01     liver/hepato:3.22    lung:4.00 bladder:3.66 kidney:3.40 pituitary:2.95 thyroid/parathyroid:3.32 adrenal gland:- pancreas:3.20 breast:3.99 salivary:3.30
RNA-seq uterus:- placenta:- prostate:2.83 ovary:2.66 testis:2.73 heart:1.60 muscle:1.42 esophagus:- stomach:- intestine:- colon:2.77     liver/hepato:1.90        lung:3.52    bladder:- kidney:2.97 pituitary:- thyroid/parathyroid:2.20 adrenal gland:2.67 pancreas:- breast:2.95 salivary:-

Gene Ontology  (GO ID)

Biological Process

GO:0002250  adaptive immune response
GO:0008219  cell death
GO:0006921  cell structure disassembly during apoptosis
GO:0006968  cellular defense response
GO:0071260  cellular response to mechanical stimulus
GO:0007249  I-kappaB kinase/NF-kappaB cascade
GO:0016064  immunoglobulin mediated immune response
GO:0045087  innate immune response
GO:0042226  interleukin-6 biosynthetic process
GO:0042109  lymphotoxin A biosynthetic process
GO:0002906  negative regulation of mature B cell apoptosis
GO:0001843  neural tube closure
GO:0043123  positive regulation of I-kappaB kinase/NF-kappaB cascade
GO:0045416  positive regulation of interleukin-8 biosynthetic process
GO:0032765  positive regulation of mast cell cytokine production
GO:0051092  positive regulation of NF-kappaB transcription factor activity
GO:0042327  positive regulation of phosphorylation
GO:0031398  positive regulation of protein ubiquitination
GO:0050870  positive regulation of T cell activation
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0051260  protein homooligomerization
GO:0051259  protein oligomerization
GO:0050856  regulation of T cell receptor signaling pathway
GO:0042221  response to chemical stimulus
GO:0009620  response to fungus
GO:0002237  response to molecule of bacterial origin
GO:0050852  T cell receptor signaling pathway
GO:0002224  toll-like receptor signaling pathway

Cellular Component

GO:0032449  CBM complex
GO:0005737  cytoplasm
GO:0005881  cytoplasmic microtubule
GO:0005829  cytosol
GO:0001772  immunological synapse
GO:0046696  lipopolysaccharide receptor complex
GO:0005764  lysosome
GO:0045121  membrane raft
GO:0005634  nucleus
GO:0048471  perinuclear region of cytoplasm
GO:0005886  plasma membrane
GO:0043234  protein complex
GO:0042101  T cell receptor complex

Molecular Function

GO:0019899  enzyme binding
GO:0019209  kinase activator activity
GO:0019900  kinase binding
GO:0051059  NF-kappaB binding
GO:0002020  protease binding
GO:0005515  protein binding
GO:0008022  protein C-terminus binding
GO:0043422  protein kinase B binding
GO:0019901  protein kinase binding
GO:0043621  protein self-association
GO:0003713  transcription coactivator activity
GO:0008134  transcription factor binding
GO:0043130  ubiquitin binding
GO:0031625  ubiquitin protein ligase binding