methyl-CpG binding domain protein 2

Synonym

MBD2, NY-CO-41, Demethylase, methyl-CpG binding domain protein 2, DMTase, DKFZp586O0821, Methyl-CpG-binding protein MBD2, Methyl-CpG-binding domain protein 2

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:19

cerebellum:25.20

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

GeneChip

cerebrum:4.96

cerebellum:3.96

brain stem:5.37

corpus callosum/glia:5.30

pineal gland:-

peripheral nerve:6.23

spine:5.63

retina:-

eye:-

artery/aorta:7.03

vein:6.81

lymphnode:7.90

peripheral blood:-

spleen:7.62

thymus:7.99

bone marrow:7.35

adipose:7.86

bone:-

skin:7.81

CAGE

cerebrum:3.22

cerebellum:-

brain stem:3.42

corpus callosum/glia:3.27

pineal gland:3.50

peripheral nerve:-

spine:3.39

retina:-

eye:-

artery/aorta:4.04

vein:4.28

lymphnode:4.66

peripheral blood:-

spleen:4.76

thymus:4.41

bone marrow:-

adipose:4.58

bone:-

skin:-

RNA-seq

cerebrum:2.86

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:4.50

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:4.20

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:9.10

placenta:-

prostate:-

ovary:-

testis:86.50

heart:-

muscle:-

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:-

lung:4.90

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

GeneChip

uterus:6.89

placenta:8.27

prostate:7.44

ovary:6.69

testis:5.97

heart:6.51

muscle:5.27

esophagus:8.27

stomach:6.97

intestine:6.90

colon:6.97

liver/hepato:6.34

lung:7.47

bladder:-

kidney:6.70

pituitary:5.74

thyroid/parathyroid:7.94

adrenal gland:6.77

pancreas:7.05

breast:7.32

salivary:7.95

CAGE

uterus:3.98

placenta:4.72

prostate:4.15

ovary:3.90

testis:3.96

heart:4.10

muscle:3.17

esophagus:4.69

stomach:-

intestine:4.43

colon:4.08

liver/hepato:4.13

lung:4.39

bladder:4.28

kidney:4.28

pituitary:3.64

thyroid/parathyroid:4.51

adrenal gland:-

pancreas:3.99

breast:4.42

salivary:4.50

RNA-seq

uterus:-

placenta:-

prostate:4.02

ovary:3.59

testis:3.33

heart:3.42

muscle:3.03

esophagus:-

stomach:-

intestine:-

colon:3.73

liver/hepato:2.92

lung:4.17

bladder:-

kidney:3.86

pituitary:-

thyroid/parathyroid:4.63

adrenal gland:4.00

pancreas:-

breast:4.88

salivary:-

IDs

Refseq ID	NM_003927
Gene ID	8932
Unigene ID	Hs.256747
Probe set ID	202484_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000134046
GTEx ID	ENSG00000134046

Orthologous Gene

Mouse[2]	NM_010773
Rat[2]	NM_010773

Chromosomal Region

18q21.2 [51,677,971 - 51,751,158]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR016177	DNA-binding, integrase-type
IPR001739	Methyl-CpG DNA binding

GO:0043623	cellular protein complex assembly
GO:0042711	maternal behavior
GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0045892	negative regulation of transcription, DNA-dependent
GO:0030177	positive regulation of Wnt receptor signaling pathway
GO:0042127	regulation of cell proliferation
GO:0006351	transcription, DNA-dependent

GO:0005737	cytoplasm
GO:0000792	heterochromatin
GO:0000118	histone deacetylase complex
GO:0005634	nucleus

GO:0070742	C2H2 zinc finger domain binding
GO:0003682	chromatin binding
GO:0008327	methyl-CpG binding
GO:0003729	mRNA binding
GO:0005515	protein binding
GO:0019904	protein domain specific binding
GO:0003696	satellite DNA binding
GO:0035197	siRNA binding

methyl-CpG binding domain protein 2

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function