wingless-type MMTV integration site family, member 3A

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Synonym

WNT3A, MGC119419, Protein Wnt-3a precursor, MGC119420, MGC119418

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:3.60 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip nodata
CAGE cerebrum:0 cerebellum:- brain stem:0 corpus callosum/glia:0 pineal gland:0 peripheral nerve:- spine:0.09 retina:- eye:- artery/aorta:0 vein:0 lymphnode:0 peripheral blood:- spleen:0 thymus:0 bone marrow:- adipose:0 bone:- skin:-
RNA-seq cerebrum:0.01 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.01 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:10.90 prostate:- ovary:37.30 testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:8.50     liver/hepato:-        lung:24.40    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip nodata
CAGE uterus:0.04 placenta:1.43 prostate:0.08 ovary:0 testis:0.12 heart:0 muscle:0 esophagus:0 stomach:- intestine:0 colon:0     liver/hepato:0    lung:0.31 bladder:0 kidney:0 pituitary:0 thyroid/parathyroid:0 adrenal gland:- pancreas:0 breast:0 salivary:0
RNA-seq uterus:- placenta:- prostate:0.11 ovary:0.04 testis:0.08 heart:0 muscle:0 esophagus:- stomach:- intestine:- colon:0     liver/hepato:0        lung:1.36    bladder:- kidney:0.06 pituitary:- thyroid/parathyroid:0 adrenal gland:0.01 pancreas:- breast:0.02 salivary:-

Gene Information

IDs

Refseq ID NM_033131
Gene ID 89780
Unigene ID Hs.336930
Probe set ID -
Ensembl ID ENSG00000154342
GTEx ID ENSG00000154342

Orthologous Gene

Mouse[1]  NM_009522
Rat[1]  NM_009522

Chromosomal Region

1q42.13  [228,194,752  -  228,248,961]

Gene Family (Interpro ID)

IPR005816  Secreted growth factor Wnt protein
IPR005817  Wnt superfamily
IPR009141  Wnt-3 protein

Link to Pubmed  (Pubmed ID)

8167409
8168088
10557084
10654605
10866835
11414706
11788904
11836627
12052822
12067714
12477932
12556519
12629517
12805222
12897152
14702039
14722104
14739301
15454084
15489334
16227623
16344560
16565323
16621789
16710414
16799642
16890161
17137849
17211448
17458904
17544413
17546602
17595165
17698587
17822920
17888180
17976063
17990294
18242164
18305214
18344425
18413325
18462958
18505824
18555765
18615587
18632632
18719101
18724388
18941195
19072540
19101069
19144919
19265664
19351711
19453261
19523451
19736317
19816934
19881541
19887570
19901330
19910923
20085589
20093360
20227366
20336604
20347274
20634891
20693288
20723538
20735988
20932509
21123170
21422228
21536751
21600099
21606194
21667018
21670201
21957254
22005028
22110662
22396540
22550094
22705156
22714865
22789636
22824791
22876125
22941468
23168335
23204070
23268410
23276938
23337036
23382209
23396967
23396968
23509994
23559372
23893409
23954131
23999248
24265322
24321072
24736394

Gene Ontology  (GO ID)

Biological Process

GO:0009653  anatomical structure morphogenesis
GO:0007411  axon guidance
GO:0003136  canonical Wnt receptor signaling pathway involved in heart induction
GO:0021846  cell proliferation in forebrain
GO:0007267  cell-cell signaling
GO:0034613  cellular protein localization
GO:0071300  cellular response to retinoic acid
GO:0021904  dorsal/ventral neural tube patterning
GO:0030198  extracellular matrix organization
GO:0001947  heart looping
GO:0030097  hemopoiesis
GO:0021766  hippocampus development
GO:0001701  in utero embryonic development
GO:0042472  inner ear morphogenesis
GO:0030879  mammary gland development
GO:0048843  negative regulation of axon extension involved in axon guidance
GO:0045599  negative regulation of fat cell differentiation
GO:0050768  negative regulation of neurogenesis
GO:0010977  negative regulation of neuron projection development
GO:0030182  neuron differentiation
GO:0001649  osteoblast differentiation
GO:0060021  palate development
GO:0048343  paraxial mesodermal cell fate commitment
GO:0070527  platelet aggregation
GO:0030890  positive regulation of B cell proliferation
GO:0043280  positive regulation of caspase activity
GO:0008284  positive regulation of cell proliferation
GO:0048697  positive regulation of collateral sprouting in the absence of injury
GO:0048337  positive regulation of mesodermal cell fate specification
GO:0033138  positive regulation of peptidyl-serine phosphorylation
GO:0001934  positive regulation of protein amino acid phosphorylation
GO:0032092  positive regulation of protein binding
GO:0002092  positive regulation of receptor internalization
GO:0051091  positive regulation of transcription factor activity
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0070507  regulation of microtubule cytoskeleton organization
GO:0010387  signalosome assembly
GO:0021527  spinal cord association neuron differentiation
GO:0021874  Wnt receptor signaling pathway in forebrain neuroblast division
GO:0060070  Wnt receptor signaling pathway through beta-catenin

Cellular Component

GO:0009986  cell surface
GO:0005788  endoplasmic reticulum lumen
GO:0005576  extracellular region
GO:0005615  extracellular space
GO:0005796  Golgi lumen
GO:0005886  plasma membrane
GO:0005578  proteinaceous extracellular matrix

Molecular Function

GO:0005201  extracellular matrix structural constituent
GO:0005109  frizzled binding
GO:0005110  frizzled-2 binding
GO:0005515  protein binding
GO:0019904  protein domain specific binding
GO:0048018  receptor agonist activity
GO:0003713  transcription coactivator activity