procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3

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Synonym

Lysyl hydroxylase 3, LH3, PLOD3, procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:93.60 cerebellum:12.60 brain stem:- corpus callosum/glia:699.90 pineal gland:- peripheral nerve:61.30 spine:112.30 retina:- eye:70.50 artery/aorta:299.80 vein:266.60 lymphnode:40.40 peripheral blood:145.70 spleen:321.40 thymus:128.80 bone marrow:78.70 adipose:80.70 bone:307.10 skin:192
GeneChip nodata
CAGE cerebrum:3.03 cerebellum:- brain stem:3.89 corpus callosum/glia:4.21 pineal gland:2.48 peripheral nerve:- spine:4.00 retina:- eye:- artery/aorta:3.13 vein:3.29 lymphnode:3.21 peripheral blood:- spleen:3.73 thymus:2.33 bone marrow:- adipose:3.95 bone:- skin:-
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:109.40 placenta:142.10 prostate:112.60 ovary:111.80 testis:30.30 heart:76.60 muscle:- esophagus:- stomach:21.20 intestine:162 colon:42.40     liver/hepato:42.20        lung:117.30    bladder:- kidney:83.20 pituitary:- thyroid/parathyroid:655 adrenal gland:304.70 pancreas:168.90 breast:65.10 salivary:-
GeneChip nodata
CAGE uterus:3.47 placenta:4.18 prostate:3.50 ovary:3.49 testis:3.03 heart:3.61 muscle:2.74 esophagus:3.15 stomach:- intestine:3.89 colon:3.71     liver/hepato:4.56    lung:3.70 bladder:3.56 kidney:3.70 pituitary:3.22 thyroid/parathyroid:3.52 adrenal gland:- pancreas:3.63 breast:4.39 salivary:2.26
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_001084000
Gene ID 8985
Unigene ID Hs.153357
Probe set ID -
Ensembl ID -
GTEx ID -

Orthologous Gene

Mouse [0]  
Rat [0]  

Chromosomal Region

7q22.1  [100,849,258  -  100,861,701]

Gene Family (Interpro ID)

IPR005123  Oxoglutarate/iron-dependent oxygenase
IPR006620  Prolyl 4-hydroxylase, alpha subunit

Link to Pubmed  (Pubmed ID)

9582318
9724729
10686427
10934207
11334715
11956192
12475640
12477932
12853948
15489334
16009940
16189514
16303743
16447251
17314511
17643375
18187620
18298658
18781797
18834968
19056867
19156129
20562859
20955792
21139048
21145461
21465473
21693764
21906983
21942715
21963094
21987572
22268729
22939629
24250222

Gene Ontology  (GO ID)

Biological Process

GO:0070831  basement membrane assembly
GO:0032870  cellular response to hormone stimulus
GO:0030199  collagen fibril organization
GO:0001886  endothelial cell morphogenesis
GO:0048730  epidermis morphogenesis
GO:0030198  extracellular matrix organization
GO:0001701  in utero embryonic development
GO:0060425  lung morphogenesis
GO:0021915  neural tube development
GO:0008104  protein localization
GO:0006464  protein modification process
GO:0042311  vasodilation

Cellular Component

GO:0005783  endoplasmic reticulum
GO:0005789  endoplasmic reticulum membrane
GO:0030867  rough endoplasmic reticulum membrane

Molecular Function

GO:0005506  iron ion binding
GO:0031418  L-ascorbic acid binding
GO:0016702  oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
GO:0050211  procollagen galactosyltransferase activity
GO:0033823  procollagen glucosyltransferase activity
GO:0008475  procollagen-lysine 5-dioxygenase activity
GO:0005515  protein binding