nucleolar protein 3 (apoptosis repressor with CARD domain)

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Synonym

Myp, NOP30, Apoptosis repressor with CARD, ARC, Muscle-enriched cytoplasmic protein, NOP, NOL3, Nop30, Nucleolar protein of 30 kDa, MYC, Nucleolar protein 3

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:92.40 cerebellum:75.60 brain stem:- corpus callosum/glia:29.20 pineal gland:- peripheral nerve:61.30 spine:- retina:- eye:64.60 artery/aorta:60 vein:- lymphnode:- peripheral blood:- spleen:397 thymus:25.80 bone marrow:19.70 adipose:- bone:25.60 skin:24
GeneChip cerebrum:6.17 cerebellum:6.20 brain stem:6.60 corpus callosum/glia:6.14 pineal gland:- peripheral nerve:6.66 spine:6.20 retina:- eye:- artery/aorta:6.70 vein:6.27 lymphnode:6.05 peripheral blood:- spleen:5.49 thymus:5.08 bone marrow:5.03 adipose:6.40 bone:- skin:6.94
CAGE cerebrum:2.62 cerebellum:- brain stem:2.97 corpus callosum/glia:2.78 pineal gland:3.24 peripheral nerve:- spine:2.61 retina:- eye:- artery/aorta:2.64 vein:1.92 lymphnode:1.86 peripheral blood:- spleen:1.71 thymus:0.80 bone marrow:- adipose:2.37 bone:- skin:-
RNA-seq cerebrum:2.30 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:1.73 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:1.92 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:69.20 prostate:67.60 ovary:74.50 testis:43.30 heart:12.80 muscle:40.20 esophagus:342.80 stomach:21.20 intestine:32.40 colon:17     liver/hepato:-        lung:9.80    bladder:- kidney:20.80 pituitary:116 thyroid/parathyroid:- adrenal gland:50.80 pancreas:35.60 breast:46.50 salivary:-
GeneChip uterus:6.26 placenta:6.54 prostate:7.54 ovary:5.77 testis:4.90 heart:6.95 muscle:7.31 esophagus:7.16 stomach:6.42 intestine:6.21 colon:5.96 liver/hepato:6.51 lung:6.52 bladder:- kidney:6 pituitary:6.86 thyroid/parathyroid:6.79 adrenal gland:7.66 pancreas:5.78 breast:6.95 salivary:7.02
CAGE uterus:2.37 placenta:2.47 prostate:2.71 ovary:2.14 testis:1.40 heart:3.01 muscle:3.60 esophagus:2.66 stomach:- intestine:1.64 colon:2.09     liver/hepato:1.90    lung:2.46 bladder:2.58 kidney:2.65 pituitary:2.76 thyroid/parathyroid:2.45 adrenal gland:- pancreas:2.18 breast:2.41 salivary:3.03
RNA-seq uterus:- placenta:- prostate:3.22 ovary:2.58 testis:1.79 heart:3.36 muscle:2.97 esophagus:- stomach:- intestine:- colon:2.03     liver/hepato:0.00        lung:2.46    bladder:- kidney:2.78 pituitary:- thyroid/parathyroid:2.62 adrenal gland:1.85 pancreas:- breast:3.34 salivary:-

Gene Information

IDs

Refseq ID NM_003946
Gene ID 8996
Unigene ID Hs.513667
Probe set ID 59625_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000140939
GTEx ID ENSG00000140939

Orthologous Gene

Mouse[1]  NM_030152
Rat [0]  

Chromosomal Region

16q22.1  [67,204,405  -  67,209,643]

Gene Family (Interpro ID)

IPR001315  Caspase Recruitment
IPR011029  DEATH-like

Link to Pubmed  (Pubmed ID)

9560245
10196175
10644725
12191471
12477932
12734105
14702039
15383280
15489334
15509781
15848180
15861191
16189514
16344560
16505176
17142452
17353931
18087040
18172857
18245485
18469522
18516683
18976975
19773279
19913121
20392691
20628086
21041716
21044950
21603976
22037876
22082675
22475487
22863883
22926851
22933109
23877130

Gene Ontology  (GO ID)

Biological Process

GO:0006915  apoptosis
GO:0006397  mRNA processing
GO:0043066  negative regulation of apoptosis
GO:0008380  RNA splicing

Cellular Component

GO:0005829  cytosol
GO:0005739  mitochondrion
GO:0005730  nucleolus
GO:0016528  sarcoplasm

Molecular Function

GO:0042802  identical protein binding
GO:0005515  protein binding
GO:0003723  RNA binding