exoribonuclease 1

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Synonym

HEXO, 3'-5' exonuclease ERI1, three prime histone mRNA exonuclease 1, Histone mRNA 3' end-specific exoribonuclease, Eri-1 homolog, ERI1, 3'EXO, 3' histone mRNA exonuclease 1, THEX1, MGC35395, 3'HEXO, Protein 3'hExo

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST nodata
GeneChip nodata
CAGE cerebrum:2.32 cerebellum:- brain stem:2.47 corpus callosum/glia:2.51 pineal gland:3.36 peripheral nerve:- spine:2.80 retina:- eye:- artery/aorta:2.74 vein:2.73 lymphnode:2.64 peripheral blood:- spleen:2.95 thymus:3.10 bone marrow:- adipose:2.95 bone:- skin:-
RNA-seq cerebrum:1.24 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:2.42 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:2.58 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST nodata
GeneChip nodata
CAGE uterus:2.89 placenta:3.74 prostate:2.64 ovary:2.65 testis:3.35 heart:2.65 muscle:2.33 esophagus:2.73 stomach:- intestine:2.60 colon:2.63     liver/hepato:2.38    lung:2.57 bladder:2.76 kidney:2.66 pituitary:2.57 thyroid/parathyroid:2.19 adrenal gland:- pancreas:1.87 breast:3.12 salivary:2.35
RNA-seq uterus:- placenta:- prostate:2.28 ovary:2.72 testis:3.45 heart:1.13 muscle:0.91 esophagus:- stomach:- intestine:- colon:2.07     liver/hepato:1.54        lung:1.71    bladder:- kidney:2.08 pituitary:- thyroid/parathyroid:1.50 adrenal gland:2.23 pancreas:- breast:2.55 salivary:-

Gene Information

IDs

Refseq ID NM_153332
Gene ID 90459
Unigene ID -
Probe set ID -
Ensembl ID ENSG00000104626
GTEx ID ENSG00000104626

Orthologous Gene

Mouse[2]  NM_026067
Rat[1]  NM_001014143

Chromosomal Region

8p23.1  [8,859,657  -  8,974,256]

Gene Family (Interpro ID)

IPR006055  Exonuclease
IPR013520  Exonuclease, RNase T/DNA polymerase III
IPR012337  Polynucleotidyl transferase, ribonuclease H fold

Link to Pubmed  (Pubmed ID)

12477932
14536070
14961122
15451662
15489334
16912046
17135487
18172165
20379614
21139048
21890473
21906983
21963094
22379092
22505724
22863883
23049088
23329046
24250222
24816145

Gene Ontology  (GO ID)

Biological Process

GO:0031047  gene silencing by RNA
GO:0071044  histone mRNA catabolic process
GO:0031125  rRNA 3'-end processing

Cellular Component

GO:0005737  cytoplasm
GO:0071204  histone pre-mRNA 3'end processing complex
GO:0005730  nucleolus
GO:0005634  nucleus

Molecular Function

GO:0008408  3'-5' exonuclease activity
GO:0071207  histone pre-mRNA stem-loop binding
GO:0046872  metal ion binding
GO:0043022  ribosome binding
GO:0019843  rRNA binding