transducin (beta)-like 1, Y-linked

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Synonym

TBL1Y, Transducin beta-like 1Y protein, Transducin-beta-like 1, Y-linked, F-box-like/WD repeat protein TBL1Y, transducin (beta)-like 1Y-linked, TBL1

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST nodata
GeneChip cerebrum:4.45 cerebellum:4.34 brain stem:4.44 corpus callosum/glia:4.33 pineal gland:- peripheral nerve:4.10 spine:4.39 retina:- eye:- artery/aorta:4.45 vein:4.62 lymphnode:4.37 peripheral blood:- spleen:4.23 thymus:4.30 bone marrow:4.32 adipose:4.43 bone:- skin:4.45
CAGE cerebrum:0.01 cerebellum:- brain stem:0.12 corpus callosum/glia:0.29 pineal gland:0 peripheral nerve:- spine:0 retina:- eye:- artery/aorta:0.95 vein:1.23 lymphnode:0.52 peripheral blood:- spleen:0 thymus:0.12 bone marrow:- adipose:0 bone:- skin:-
RNA-seq cerebrum:0.00 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.00 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.00 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST nodata
GeneChip uterus:4.47 placenta:4.13 prostate:4.90 ovary:4.42 testis:4.32 heart:4.38 muscle:4.53 esophagus:4.38 stomach:4.28 intestine:4.40 colon:4.23 liver/hepato:4.61 lung:4.28 bladder:- kidney:4.84 pituitary:4.37 thyroid/parathyroid:5.20 adrenal gland:4.41 pancreas:4.80 breast:4.36 salivary:4.49
CAGE uterus:0 placenta:0 prostate:1.61 ovary:0 testis:0.81 heart:0.33 muscle:0.25 esophagus:0.52 stomach:- intestine:0.21 colon:0.12     liver/hepato:0.90    lung:0.87 bladder:0 kidney:0 pituitary:0 thyroid/parathyroid:1.81 adrenal gland:- pancreas:2.08 breast:0 salivary:0.83
RNA-seq uterus:- placenta:- prostate:0.00 ovary:0.00 testis:0.00 heart:0.00 muscle:0.00 esophagus:- stomach:- intestine:- colon:0.00     liver/hepato:0.14        lung:0.00    bladder:- kidney:0.00 pituitary:- thyroid/parathyroid:0.00 adrenal gland:0.00 pancreas:- breast:0.00 salivary:-

Gene Information

IDs

Refseq ID NM_134258
Gene ID 90665
Unigene ID -
Probe set ID 211462_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000092377
GTEx ID ENSG00000092377

Orthologous Gene

Mouse[3]  NM_020601
Rat [0]  

Chromosomal Region

Yp11.2  [6,778,727  -  6,959,977]

Gene Family (Interpro ID)

IPR020472  G-protein beta WD-40 repeat, region
IPR006594  LisH dimerisation motif
IPR001680  WD40 repeat
IPR019782  WD40 repeat 2
IPR019781  WD40 repeat, subgroup
IPR011046  WD40 repeat-like-containing domain
IPR017986  WD40-repeat-containing domain
IPR015943  WD40/YVTN repeat-like-containing domain

Link to Pubmed  (Pubmed ID)

12477932
12815422
14660691
14702039
18511697
19605777
21189284
22280357
24457600

Gene Ontology  (GO ID)

Biological Process

GO:0045444  fat cell differentiation
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0043161  proteasomal ubiquitin-dependent protein catabolic process
GO:0043627  response to estrogen stimulus
GO:0006351  transcription, DNA-dependent

Cellular Component

GO:0005667  transcription factor complex

Molecular Function

GO:0003682  chromatin binding
GO:0044212  DNA regulatory region binding
GO:0003714  transcription corepressor activity