DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57

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Synonym

DEAH box protein 57, DDX57, Putative ATP-dependent RNA helicase DHX57, FLJ32861, DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57, DHX57

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:16.60 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:30.70 spine:112.30 retina:237.30 eye:- artery/aorta:30 vein:133.30 lymphnode:60.70 peripheral blood:18.20 spleen:18.90 thymus:- bone marrow:- adipose:- bone:12.80 skin:28.80
GeneChip cerebrum:6.16 cerebellum:6.15 brain stem:6.01 corpus callosum/glia:6.14 pineal gland:- peripheral nerve:6.16 spine:6.08 retina:- eye:- artery/aorta:5.99 vein:6.25 lymphnode:6 peripheral blood:- spleen:5.77 thymus:6.09 bone marrow:5.76 adipose:6.14 bone:- skin:6
CAGE cerebrum:2.48 cerebellum:- brain stem:2.42 corpus callosum/glia:2.61 pineal gland:2.71 peripheral nerve:- spine:1.99 retina:- eye:- artery/aorta:2.30 vein:2.22 lymphnode:2.37 peripheral blood:- spleen:2.53 thymus:2.68 bone marrow:- adipose:2.47 bone:- skin:-
RNA-seq cerebrum:2.47 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:1.41 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:2.01 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:10.90 prostate:- ovary:- testis:64.90 heart:- muscle:- esophagus:- stomach:- intestine:- colon:50.90     liver/hepato:21.10        lung:29.30    bladder:- kidney:20.80 pituitary:116 thyroid/parathyroid:- adrenal gland:- pancreas:35.60 breast:18.60 salivary:-
GeneChip uterus:6.33 placenta:6.41 prostate:5.97 ovary:6.42 testis:7.37 heart:6.06 muscle:5.97 esophagus:6.03 stomach:6.08 intestine:6.05 colon:5.78 liver/hepato:5.72 lung:5.83 bladder:- kidney:5.95 pituitary:6.47 thyroid/parathyroid:5.99 adrenal gland:6.17 pancreas:6.06 breast:6.16 salivary:5.92
CAGE uterus:2.94 placenta:2.54 prostate:2.68 ovary:2.74 testis:3.67 heart:2.21 muscle:2.53 esophagus:2.41 stomach:- intestine:2.07 colon:2.34     liver/hepato:1.86    lung:2.30 bladder:2.63 kidney:2.45 pituitary:3.10 thyroid/parathyroid:2.46 adrenal gland:- pancreas:2.41 breast:1.92 salivary:2.35
RNA-seq uterus:- placenta:- prostate:2.67 ovary:3.14 testis:3.91 heart:1.65 muscle:2.56 esophagus:- stomach:- intestine:- colon:1.83     liver/hepato:1.42        lung:1.34    bladder:- kidney:2.10 pituitary:- thyroid/parathyroid:2.77 adrenal gland:2.45 pancreas:- breast:2.24 salivary:-

Gene Information

IDs

Refseq ID NM_198963
Gene ID 90957
Unigene ID Hs.468226
Probe set ID 213420_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000163214
GTEx ID ENSG00000163214

Orthologous Gene

Mouse[2]  NM_001163759, NM_198942
Rat [0]  

Chromosomal Region

2p22.1  [39,024,871  -  39,103,075]

Gene Family (Interpro ID)

IPR014001  DEAD-like helicase, N-terminal
IPR014021  Helicase, superfamily 1/2, ATP-binding domain
IPR000449  Ubiquitin-associated/translation elongation factor EF1B, N-terminal
IPR015940  Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote

Link to Pubmed  (Pubmed ID)

8619474
9110174
12477932
14702039
15489334
15815621
17081983
17353931
20020773
21139048
21145461
22586326
22990118
23251661
24778252
24816145

Gene Ontology  (GO ID)

Molecular Function

GO:0005524  ATP binding
GO:0008026  ATP-dependent helicase activity
GO:0046872  metal ion binding
GO:0003676  nucleic acid binding