activin A receptor, type IB

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ALK-4, ACVRLK4, ACVR1B, Activin receptor type 1B precursor, Activin receptor-like kinase 4, ALK4, activin A receptor, type IB, Serine/threonine-protein kinase receptor R2, SKR2, ACTR-IB, ACTRIB

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:83 cerebellum:37.80 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:52.90 artery/aorta:- vein:- lymphnode:10.10 peripheral blood:18.20 spleen:18.90 thymus:25.80 bone marrow:59 adipose:- bone:- skin:76.80
GeneChip cerebrum:7.67 cerebellum:7.68 brain stem:7.54 corpus callosum/glia:6.60 pineal gland:- peripheral nerve:7.28 spine:7 retina:- eye:- artery/aorta:7.05 vein:7.19 lymphnode:6.83 peripheral blood:- spleen:6.62 thymus:6.33 bone marrow:6.66 adipose:7.23 bone:- skin:8.16
CAGE cerebrum:2.90 cerebellum:- brain stem:2.24 corpus callosum/glia:2.14 pineal gland:2.90 peripheral nerve:- spine:2.21 retina:- eye:- artery/aorta:2.95 vein:2.11 lymphnode:2.55 peripheral blood:- spleen:2.23 thymus:1.75 bone marrow:- adipose:2.61 bone:- skin:-
RNA-seq cerebrum:3.78 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:2.10 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:2.25 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:9.10 placenta:18.20 prostate:56.30 ovary:37.30 testis:47.60 heart:25.50 muscle:20.10 esophagus:- stomach:85 intestine:- colon:93.30     liver/hepato:10.60        lung:29.30    bladder:- kidney:135.20 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:53.30 breast:195.20 salivary:-
GeneChip uterus:6.92 placenta:6.09 prostate:7.85 ovary:7.36 testis:7.62 heart:7.07 muscle:7.14 esophagus:7.76 stomach:7.37 intestine:7.57 colon:7.65 liver/hepato:7.66 lung:7.21 bladder:- kidney:8.93 pituitary:7.59 thyroid/parathyroid:7.35 adrenal gland:6.81 pancreas:8 breast:7.72 salivary:8.46
CAGE uterus:2.34 placenta:1.39 prostate:2.66 ovary:2.43 testis:2.73 heart:2.43 muscle:2.64 esophagus:2.79 stomach:- intestine:3.33 colon:3.37     liver/hepato:3.18    lung:2.61 bladder:2.55 kidney:3.43 pituitary:2.87 thyroid/parathyroid:2.65 adrenal gland:- pancreas:3.78 breast:3.02 salivary:3.45
RNA-seq uterus:- placenta:- prostate:3.29 ovary:2.36 testis:3.25 heart:1.98 muscle:2.65 esophagus:- stomach:- intestine:- colon:2.63     liver/hepato:3.24        lung:3.06    bladder:- kidney:4.36 pituitary:- thyroid/parathyroid:2.90 adrenal gland:2.47 pancreas:- breast:1.68 salivary:-

Gene Ontology  (GO ID)

Biological Process

GO:0032924  activin receptor signaling pathway
GO:0007417  central nervous system development
GO:0046545  development of primary female sexual characteristics
GO:0000082  G1/S transition of mitotic cell cycle
GO:0001942  hair follicle development
GO:0001701  in utero embryonic development
GO:0030308  negative regulation of cell growth
GO:0018107  peptidyl-threonine phosphorylation
GO:0032927  positive regulation of activin receptor signaling pathway
GO:0045648  positive regulation of erythrocyte differentiation
GO:0010862  positive regulation of pathway-restricted SMAD protein phosphorylation
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0046777  protein amino acid autophosphorylation
GO:0006468  protein amino acid phosphorylation
GO:0006355  regulation of transcription, DNA-dependent
GO:0007165  signal transduction
GO:0007178  transmembrane receptor protein serine/threonine kinase signaling pathway

Cellular Component

GO:0009986  cell surface
GO:0005887  integral to plasma membrane
GO:0005886  plasma membrane

Molecular Function

GO:0048185  activin binding
GO:0017002  activin receptor activity
GO:0016361  activin receptor activity, type I
GO:0005524  ATP binding
GO:0019838  growth factor binding
GO:0034711  inhibin binding
GO:0046872  metal ion binding
GO:0005515  protein binding
GO:0004674  protein serine/threonine kinase activity
GO:0004702  receptor signaling protein serine/threonine kinase activity
GO:0046332  SMAD binding
GO:0005024  transforming growth factor beta receptor activity
GO:0004675  transmembrane receptor protein serine/threonine kinase activity
GO:0031625  ubiquitin protein ligase binding