ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1

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Synonym

Vma6, Vacuolar ATP synthase subunit d, Vacuolar proton pump subunit d, VPATPD, ATP6V0D1, V-ATPase d subunit, ATP6DV, V-ATPase 40 kDa accessory protein, VMA6, P39, 32 kDa accessory protein, lysosomal 38kDa, VATX, V-ATPase AC39 subunit, ATP6D

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:209.80 cerebellum:188.90 brain stem:- corpus callosum/glia:87.50 pineal gland:296.70 peripheral nerve:61.30 spine:224.60 retina:118.60 eye:94 artery/aorta:60 vein:399.90 lymphnode:30.30 peripheral blood:327.90 spleen:151.30 thymus:103.10 bone marrow:255.80 adipose:80.70 bone:38.40 skin:148.80
GeneChip cerebrum:9.26 cerebellum:9.02 brain stem:9.69 corpus callosum/glia:8.41 pineal gland:- peripheral nerve:9.29 spine:8.65 retina:- eye:- artery/aorta:8.58 vein:8.08 lymphnode:8.58 peripheral blood:- spleen:8.71 thymus:8.43 bone marrow:9.25 adipose:8.37 bone:- skin:8.90
CAGE cerebrum:4.68 cerebellum:- brain stem:4.67 corpus callosum/glia:4.59 pineal gland:4.42 peripheral nerve:- spine:3.82 retina:- eye:- artery/aorta:3.87 vein:3.85 lymphnode:4.32 peripheral blood:- spleen:4.36 thymus:4.14 bone marrow:- adipose:4.21 bone:- skin:-
RNA-seq cerebrum:5.64 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:5.05 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:4.95 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:45.60 placenta:149.40 prostate:78.90 ovary:74.50 testis:173.10 heart:140.50 muscle:120.50 esophagus:342.80 stomach:169.90 intestine:129.60 colon:169.60     liver/hepato:84.40        lung:73.30    bladder:- kidney:83.20 pituitary:116 thyroid/parathyroid:- adrenal gland:457.10 pancreas:80 breast:102.20 salivary:-
GeneChip uterus:8.67 placenta:8.19 prostate:9 ovary:8.20 testis:9.23 heart:7.97 muscle:8.70 esophagus:8.94 stomach:8.35 intestine:8.42 colon:8.89 liver/hepato:8.20 lung:8.91 bladder:- kidney:9.15 pituitary:9.39 thyroid/parathyroid:8.78 adrenal gland:8.70 pancreas:7.86 breast:8.58 salivary:8.07
CAGE uterus:4.01 placenta:4.31 prostate:3.98 ovary:3.89 testis:4.81 heart:3.75 muscle:4.24 esophagus:4.11 stomach:- intestine:4.38 colon:4.31     liver/hepato:4.26    lung:4.38 bladder:3.69 kidney:4.52 pituitary:4.44 thyroid/parathyroid:4.49 adrenal gland:- pancreas:3.82 breast:3.95 salivary:4.29
RNA-seq uterus:- placenta:- prostate:4.99 ovary:5.03 testis:5.77 heart:4.13 muscle:5.27 esophagus:- stomach:- intestine:- colon:4.40     liver/hepato:4.74        lung:5.25    bladder:- kidney:5.77 pituitary:- thyroid/parathyroid:5.76 adrenal gland:5.16 pancreas:- breast:4.96 salivary:-

Gene Information

IDs

Refseq ID NM_004691
Gene ID 9114
Unigene ID Hs.106876
Probe set ID 212041_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000159720
GTEx ID ENSG00000159720

Orthologous Gene

Mouse[1]  NM_013477
Rat[1]  NM_001011927

Chromosomal Region

16q22.1  [67,471,922  -  67,515,140]

Gene Family (Interpro ID)

IPR016727  ATPase, V0 complex, subunit D
IPR002843  ATPase, V0/A0 complex, subunit C/D

Link to Pubmed  (Pubmed ID)

2874839
2903164
8250920
8889548
9210392
9442887
10221984
10224039
10340843
10440860
11118322
11836511
12477932
12788495
14580332
14597263
14702039
15489334
16196087
16713569
17662945
17897319
18752060
19056867
19165527
19285986
19913121
20628086
21139048
21674799
21890473
21906983
21963094
21987572
22505724
22939629
22990118
23125841
24250222
24332808

Gene Ontology  (GO ID)

Biological Process

GO:0006987  activation of signaling protein activity involved in unfolded protein response
GO:0015991  ATP hydrolysis coupled proton transport
GO:0007420  brain development
GO:0006879  cellular iron ion homeostasis
GO:0044267  cellular protein metabolic process
GO:0042384  cilium assembly
GO:0030968  endoplasmic reticulum unfolded protein response
GO:0008286  insulin receptor signaling pathway
GO:0051701  interaction with host
GO:0015992  proton transport
GO:0033572  transferrin transport
GO:0055085  transmembrane transport

Cellular Component

GO:0016324  apical plasma membrane
GO:0005813  centrosome
GO:0005769  early endosome
GO:0010008  endosome membrane
GO:0016020  membrane
GO:0043679  nerve terminal
GO:0030670  phagocytic vesicle membrane
GO:0033179  proton-transporting V-type ATPase, V0 domain
GO:0008021  synaptic vesicle
GO:0016471  vacuolar proton-transporting V-type ATPase complex

Molecular Function

GO:0008553  hydrogen-exporting ATPase activity, phosphorylative mechanism
GO:0005515  protein binding
GO:0032403  protein complex binding