apoptosis-inducing factor, mitochondrion-associated, 1

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Synonym

MGC111425, AIF, PDCD8, Apoptosis-inducing factor

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:45

cerebellum:100.80

brain stem:-

corpus callosum/glia:175

pineal gland:-

peripheral nerve:61.30

spine:-

retina:118.60

eye:35.30

artery/aorta:30

vein:-

lymphnode:50.60

peripheral blood:109.30

spleen:94.50

thymus:193.30

bone marrow:78.70

adipose:80.70

bone:38.40

skin:72

GeneChip

cerebrum:5.93

cerebellum:6.27

brain stem:5.97

corpus callosum/glia:5.88

pineal gland:-

peripheral nerve:5.84

spine:5.87

retina:-

eye:-

artery/aorta:5.99

vein:6.46

lymphnode:6.07

peripheral blood:-

spleen:5.97

thymus:6.53

bone marrow:5.94

adipose:6.51

bone:-

skin:6.11

CAGE

cerebrum:2.75

cerebellum:-

brain stem:2.91

corpus callosum/glia:2.95

pineal gland:2.58

peripheral nerve:-

spine:2.66

retina:-

eye:-

artery/aorta:2.43

vein:2.96

lymphnode:3.08

peripheral blood:-

spleen:2.88

thymus:3.53

bone marrow:-

adipose:3.11

bone:-

skin:-

RNA-seq

cerebrum:0.33

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:0.11

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:0.31

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:27.30

placenta:72.90

prostate:33.80

ovary:74.50

testis:99.50

heart:140.50

muscle:60.30

esophagus:-

stomach:85

intestine:194.40

colon:76.30

liver/hepato:73.90

lung:39.10

bladder:628.10

kidney:467.90

pituitary:-

thyroid/parathyroid:491.20

adrenal gland:203.10

pancreas:44.50

breast:74.30

salivary:-

GeneChip

uterus:6.43

placenta:5.97

prostate:6.32

ovary:6.88

testis:7

heart:7.10

muscle:7.55

esophagus:6.45

stomach:6.46

intestine:6.91

colon:6.77

liver/hepato:7.39

lung:5.83

bladder:-

kidney:8.13

pituitary:6.10

thyroid/parathyroid:5.88

adrenal gland:6.81

pancreas:6.53

breast:6.38

salivary:6.19

CAGE

uterus:2.95

placenta:2.56

prostate:2.82

ovary:2.77

testis:3.45

heart:3.82

muscle:3.86

esophagus:2.95

stomach:-

intestine:3.87

colon:3.16

liver/hepato:4.47

lung:2.75

bladder:2.93

kidney:4.89

pituitary:2.87

thyroid/parathyroid:2.85

adrenal gland:-

pancreas:3.42

breast:2.64

salivary:3.50

RNA-seq

uterus:-

placenta:-

prostate:0.53

ovary:0.55

testis:0.10

heart:0.47

muscle:0

esophagus:-

stomach:-

intestine:-

colon:0.14

liver/hepato:0

lung:0.59

bladder:-

kidney:0.11

pituitary:-

thyroid/parathyroid:0.17

adrenal gland:0.51

pancreas:-

breast:0.25

salivary:-

IDs

Refseq ID	NM_001130846
Gene ID	9131
Unigene ID	Hs.424932
Probe set ID	205512_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000156709
GTEx ID	ENSG00000156709

Orthologous Gene

Mouse[1]	NM_012019
Rat [0]

Chromosomal Region

Xq26.1 [129,263,337 - 129,299,861]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR013027

FAD-dependent pyridine nucleotide-disulphide oxidoreductase

GO:0006919	activation of caspase activity
GO:0006915	apoptosis
GO:0070059	apoptosis in response to endoplasmic reticulum stress
GO:0045454	cell redox homeostasis
GO:0006309	DNA fragmentation involved in apoptosis
GO:0032981	mitochondrial respiratory chain complex I assembly
GO:0051402	neuron apoptosis
GO:0030182	neuron differentiation

GO:0005829	cytosol
GO:0005743	mitochondrial inner membrane
GO:0005758	mitochondrial intermembrane space
GO:0005739	mitochondrion
GO:0005634	nucleus
GO:0048471	perinuclear region of cytoplasm

GO:0003677	DNA binding
GO:0009055	electron carrier activity
GO:0050660	FAD binding
GO:0016651	oxidoreductase activity, acting on NADH or NADPH
GO:0005515	protein binding

apoptosis-inducing factor, mitochondrion-associated, 1

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function