core-binding factor, runt domain, alpha subunit 2; translocated to, 2

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Synonym

Protein CBFA2T2, MTG8-like protein, ZMYND3, MTG8-related protein 1, DKFZp313F2116, ETO homologous on chromosome 20, MTGR1, CBFA2T2, EHT, Myeloid translocation-related protein 1

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:88.90 cerebellum:88.20 brain stem:- corpus callosum/glia:- pineal gland:148.30 peripheral nerve:92 spine:- retina:- eye:111.70 artery/aorta:- vein:- lymphnode:60.70 peripheral blood:- spleen:56.70 thymus:77.30 bone marrow:118.10 adipose:40.30 bone:12.80 skin:76.80
GeneChip cerebrum:6.89 cerebellum:6.52 brain stem:6.92 corpus callosum/glia:6.96 pineal gland:- peripheral nerve:6.05 spine:6.80 retina:- eye:- artery/aorta:6.22 vein:6.14 lymphnode:6.33 peripheral blood:- spleen:6.39 thymus:6.41 bone marrow:5.98 adipose:6.33 bone:- skin:6.61
CAGE cerebrum:3.51 cerebellum:- brain stem:3.62 corpus callosum/glia:3.84 pineal gland:3.41 peripheral nerve:- spine:3.41 retina:- eye:- artery/aorta:2.79 vein:2.71 lymphnode:2.91 peripheral blood:- spleen:2.70 thymus:3.25 bone marrow:- adipose:2.68 bone:- skin:-
RNA-seq cerebrum:1.66 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.00 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.00 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:36.50 placenta:47.40 prostate:281.60 ovary:223.60 testis:108.20 heart:102.20 muscle:- esophagus:- stomach:297.40 intestine:64.80 colon:144.20     liver/hepato:84.40        lung:127.10    bladder:- kidney:20.80 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:124.50 breast:46.50 salivary:-
GeneChip uterus:6.51 placenta:5.88 prostate:7.58 ovary:6.62 testis:6.54 heart:6.44 muscle:6.71 esophagus:6.43 stomach:6.37 intestine:6.40 colon:6.72 liver/hepato:6.32 lung:5.86 bladder:- kidney:6.57 pituitary:6.72 thyroid/parathyroid:6.71 adrenal gland:6.12 pancreas:6.28 breast:6.41 salivary:6.45
CAGE uterus:3.24 placenta:2.81 prostate:3.40 ovary:3.07 testis:3.02 heart:2.52 muscle:2.40 esophagus:2.95 stomach:- intestine:3.18 colon:3.51     liver/hepato:2.14    lung:2.74 bladder:2.98 kidney:2.87 pituitary:3.29 thyroid/parathyroid:2.98 adrenal gland:- pancreas:2.41 breast:2.83 salivary:3.30
RNA-seq uterus:- placenta:- prostate:1.08 ovary:0.00 testis:0.18 heart:0.16 muscle:0.00 esophagus:- stomach:- intestine:- colon:0.00     liver/hepato:0.00        lung:0.63    bladder:- kidney:0.00 pituitary:- thyroid/parathyroid:0.00 adrenal gland:1.09 pancreas:- breast:0.00 salivary:-

Gene Information

IDs

Refseq ID NM_001039709
Gene ID 9139
Unigene ID Hs.153934
Probe set ID 207625_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000078699
GTEx ID ENSG00000078699

Orthologous Gene

Mouse[2]  NM_009823, NM_172860
Rat[1]  NM_001168542, NM_172860

Chromosomal Region

20q11.21  [32,077,881  -  32,237,842]

Gene Family (Interpro ID)

IPR013289  Eight-Twenty-One
IPR013291  Myeloid transforming gene related protein-1 (MTGR1)

Link to Pubmed  (Pubmed ID)

9447981
9787195
9790752
10675041
11780052
12242670
12477932
14703694
15146197
15302935
15333839
15489334
16189514
16227606
16407974
16713569
16966434
18586123
19026687
19060904
20211142
20520637
21832049
21988832
22443175
22498736

Gene Ontology  (GO ID)

Biological Process

GO:0030855  epithelial cell differentiation
GO:0010977  negative regulation of neuron projection development
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0010976  positive regulation of neuron projection development
GO:0045944  positive regulation of transcription from RNA polymerase II promoter

Cellular Component

GO:0005634  nucleus

Molecular Function

GO:0046872  metal ion binding
GO:0005515  protein binding
GO:0003714  transcription corepressor activity
GO:0003700  transcription factor activity