mitogen-activated protein kinase-activated protein kinase 2

jump to detail

Synonym

MAPK-activated protein kinase 2, MK2, MAPKAPK2, MAPKAP kinase 2, MAP kinase-activated protein kinase 2, MAPKAPK-2

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST nodata
GeneChip cerebrum:6.78 cerebellum:6.79 brain stem:6.85 corpus callosum/glia:7.21 pineal gland:- peripheral nerve:6.98 spine:7.30 retina:- eye:- artery/aorta:7.80 vein:7.92 lymphnode:7.77 peripheral blood:- spleen:7.75 thymus:7.27 bone marrow:7.55 adipose:7.52 bone:- skin:7.52
CAGE cerebrum:3.38 cerebellum:- brain stem:3.75 corpus callosum/glia:3.95 pineal gland:4.88 peripheral nerve:- spine:3.76 retina:- eye:- artery/aorta:4.21 vein:4.05 lymphnode:4.28 peripheral blood:- spleen:4.69 thymus:4.20 bone marrow:- adipose:4.27 bone:- skin:-
RNA-seq cerebrum:3.23 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:5.12 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:4.96 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST nodata
GeneChip uterus:7.36 placenta:6.90 prostate:6.89 ovary:7.40 testis:7.41 heart:8.38 muscle:8.01 esophagus:7.63 stomach:7.82 intestine:7.70 colon:7.57 liver/hepato:7.51 lung:7.81 bladder:- kidney:7.98 pituitary:7.56 thyroid/parathyroid:7.60 adrenal gland:8.09 pancreas:7.16 breast:7.72 salivary:7.59
CAGE uterus:4.01 placenta:3.61 prostate:4.12 ovary:4.24 testis:4.24 heart:5.08 muscle:4.71 esophagus:4.24 stomach:- intestine:4.54 colon:4.04     liver/hepato:4.21    lung:4.37 bladder:4.21 kidney:4.55 pituitary:4.11 thyroid/parathyroid:4.21 adrenal gland:- pancreas:3.90 breast:4.34 salivary:4.01
RNA-seq uterus:- placenta:- prostate:4.50 ovary:4.54 testis:4.48 heart:5.72 muscle:5.46 esophagus:- stomach:- intestine:- colon:4.26     liver/hepato:3.81        lung:5.69    bladder:- kidney:5.09 pituitary:- thyroid/parathyroid:5.17 adrenal gland:5.01 pancreas:- breast:4.33 salivary:-

IDs

Refseq ID NM_032960
Gene ID 9261
Unigene ID -
Probe set ID 201460_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000162889
GTEx ID ENSG00000162889

Orthologous Gene

Mouse[1]  NM_008551
Rat [0]  

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed  (Pubmed ID)

Gene Ontology  (GO ID)

Biological Process

GO:0070935  3'-UTR-mediated mRNA stabilization
GO:0000187  activation of MAPK activity
GO:0019369  arachidonic acid metabolic process
GO:0031572  G2/M transition DNA damage checkpoint
GO:0010467  gene expression
GO:0006954  inflammatory response
GO:0045087  innate immune response
GO:0048839  inner ear development
GO:0006691  leukotriene metabolic process
GO:0000165  MAPKKK cascade
GO:0016071  mRNA metabolic process
GO:0002755  MyD88-dependent toll-like receptor signaling pathway
GO:0002756  MyD88-independent toll-like receptor signaling pathway
GO:0048011  nerve growth factor receptor signaling pathway
GO:0018105  peptidyl-serine phosphorylation
GO:0006468  protein amino acid phosphorylation
GO:0007265  Ras protein signal transduction
GO:0032675  regulation of interleukin-6 production
GO:0032680  regulation of tumor necrosis factor production
GO:0006974  response to DNA damage stimulus
GO:0032496  response to lipopolysaccharide
GO:0006950  response to stress
GO:0016070  RNA metabolic process
GO:0051403  stress-activated MAPK cascade
GO:0034166  toll-like receptor 10 signaling pathway
GO:0034134  toll-like receptor 2 signaling pathway
GO:0034138  toll-like receptor 3 signaling pathway
GO:0034142  toll-like receptor 4 signaling pathway
GO:0034146  toll-like receptor 5 signaling pathway
GO:0034162  toll-like receptor 9 signaling pathway
GO:0002224  toll-like receptor signaling pathway
GO:0048010  vascular endothelial growth factor receptor signaling pathway

Cellular Component

GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0005654  nucleoplasm
GO:0005634  nucleus

Molecular Function

GO:0005524  ATP binding
GO:0005515  protein binding
GO:0004672  protein kinase activity
GO:0004674  protein serine/threonine kinase activity
GO:0004871  signal transducer activity