delta/notch-like EGF repeat containing

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Synonym

delta/notch-like EGF repeat containing, UNQ26, DNER

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:145.80 cerebellum:113.30 brain stem:- corpus callosum/glia:58.30 pineal gland:- peripheral nerve:153.40 spine:- retina:830.50 eye:94 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:12.80 skin:33.60
GeneChip nodata
CAGE cerebrum:4.86 cerebellum:- brain stem:5.31 corpus callosum/glia:5.54 pineal gland:2.87 peripheral nerve:- spine:5.16 retina:- eye:- artery/aorta:0.95 vein:0.88 lymphnode:0.38 peripheral blood:- spleen:0.32 thymus:0.23 bone marrow:- adipose:0.63 bone:- skin:-
RNA-seq cerebrum:6.09 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.73 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.27 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:7.30 prostate:11.30 ovary:- testis:4.30 heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:4.90    bladder:- kidney:41.60 pituitary:- thyroid/parathyroid:- adrenal gland:50.80 pancreas:8.90 breast:46.50 salivary:-
GeneChip nodata
CAGE uterus:1.08 placenta:1.22 prostate:0.97 ovary:0.68 testis:0.81 heart:1.36 muscle:0.13 esophagus:0.73 stomach:- intestine:0.38 colon:1.43     liver/hepato:0    lung:1.02 bladder:1.06 kidney:3.30 pituitary:3.89 thyroid/parathyroid:0 adrenal gland:- pancreas:0.94 breast:0.55 salivary:4.23
RNA-seq uterus:- placenta:- prostate:1.01 ovary:0.26 testis:1.12 heart:0.67 muscle:0.45 esophagus:- stomach:- intestine:- colon:2.77     liver/hepato:0.06        lung:1.73    bladder:- kidney:3.95 pituitary:- thyroid/parathyroid:0.30 adrenal gland:0.02 pancreas:- breast:0.30 salivary:-

Gene Information

IDs

Refseq ID NM_139072
Gene ID 92737
Unigene ID Hs.234074
Probe set ID -
Ensembl ID ENSG00000187957
GTEx ID ENSG00000187957

Orthologous Gene

Mouse[2]  NM_152915
Rat[2]  NM_152915

Chromosomal Region

2q36.3  [230,222,345  -  230,579,274]

Gene Family (Interpro ID)

IPR001881  EGF-like calcium-binding
IPR000742  EGF-like, type 3

Link to Pubmed  (Pubmed ID)

9847074
11950833
11997712
12477932
12975309
15489334
15815621
16344560
16740002
20070733
20237496
20367751
23284291
23382691
23383108
24101674

Gene Ontology  (GO ID)

Biological Process

GO:0007417  central nervous system development
GO:0006897  endocytosis
GO:0010001  glial cell differentiation
GO:0001764  neuron migration
GO:0007220  Notch receptor processing
GO:0007219  Notch signaling pathway
GO:0048741  skeletal muscle fiber development
GO:0007416  synapse assembly

Cellular Component

GO:0043025  cell soma
GO:0030425  dendrite
GO:0005769  early endosome
GO:0016021  integral to membrane
GO:0005886  plasma membrane

Molecular Function

GO:0005509  calcium ion binding
GO:0030276  clathrin binding
GO:0005112  Notch binding
GO:0005515  protein binding
GO:0004888  transmembrane receptor activity