thyroid hormone receptor interactor 12

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Synonym

KIAA0045, thyroid hormone receptor interactor 12, MGC138850, Thyroid receptor-interacting protein 12, TRIP12, MGC138849

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:55.70 cerebellum:63 brain stem:- corpus callosum/glia:116.60 pineal gland:148.30 peripheral nerve:92 spine:224.60 retina:118.60 eye:94 artery/aorta:149.90 vein:- lymphnode:161.80 peripheral blood:36.40 spleen:56.70 thymus:141.70 bone marrow:118.10 adipose:40.30 bone:51.20 skin:105.60
GeneChip cerebrum:7.84 cerebellum:6.70 brain stem:8.09 corpus callosum/glia:8.07 pineal gland:- peripheral nerve:8.02 spine:8 retina:- eye:- artery/aorta:7.93 vein:7.94 lymphnode:8.38 peripheral blood:- spleen:8.23 thymus:9.04 bone marrow:8.43 adipose:8.10 bone:- skin:8.35
CAGE cerebrum:4.05 cerebellum:- brain stem:4.26 corpus callosum/glia:4.34 pineal gland:4.15 peripheral nerve:- spine:4.23 retina:- eye:- artery/aorta:4.16 vein:4.07 lymphnode:4.28 peripheral blood:- spleen:4.50 thymus:4.61 bone marrow:- adipose:4.42 bone:- skin:-
RNA-seq cerebrum:4.19 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:4.44 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:5.10 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:100.20 placenta:58.30 prostate:56.30 ovary:37.30 testis:125.50 heart:153.30 muscle:20.10 esophagus:- stomach:127.50 intestine:97.20 colon:42.40     liver/hepato:95        lung:136.90    bladder:376.80 kidney:10.40 pituitary:- thyroid/parathyroid:163.70 adrenal gland:101.60 pancreas:35.60 breast:185.90 salivary:-
GeneChip uterus:8.19 placenta:8.10 prostate:8.72 ovary:8.24 testis:10.33 heart:7.98 muscle:8.22 esophagus:8.48 stomach:7.83 intestine:7.71 colon:7.29 liver/hepato:7.30 lung:8.20 bladder:- kidney:7.71 pituitary:7.97 thyroid/parathyroid:8.03 adrenal gland:7.86 pancreas:7.20 breast:8.10 salivary:7.91
CAGE uterus:4.23 placenta:4.25 prostate:4.17 ovary:4.08 testis:4.72 heart:4.33 muscle:4.21 esophagus:4.26 stomach:- intestine:4.04 colon:4.04     liver/hepato:4.10    lung:4.06 bladder:4.32 kidney:4.19 pituitary:4.45 thyroid/parathyroid:4.04 adrenal gland:- pancreas:3.82 breast:4.04 salivary:4.26
RNA-seq uterus:- placenta:- prostate:4.49 ovary:4.75 testis:6.08 heart:4.46 muscle:4.84 esophagus:- stomach:- intestine:- colon:4.75     liver/hepato:3.35        lung:4.67    bladder:- kidney:4.63 pituitary:- thyroid/parathyroid:4.90 adrenal gland:4.33 pancreas:- breast:4.78 salivary:-

Gene Information

IDs

Refseq ID NM_004238
Gene ID 9320
Unigene ID Hs.591633
Probe set ID 201546_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000153827
GTEx ID ENSG00000153827

Orthologous Gene

Mouse[5]  NM_133975
Rat [0]  

Chromosomal Region

2q36.3  [230,631,930  -  230,787,955]

Gene Family (Interpro ID)

IPR004170  WWE domain
IPR018123  WWE domain, subgroup

Link to Pubmed  (Pubmed ID)

7584044
7776974
8889548
9575161
12421765
12477932
14702039
15231748
15302935
16344560
16964243
17081983
17110338
17643375
18627766
19028681
19596686
19615732
19730683
20208519
20379614
20699639
20829358
21139048
21182205
21890473
21906983
22053931
22124266
22505724
22561347
22586326
22884692
22939629
23000965
23034180
23209776
23383273
23663701
24332808
24457600
24769896
24816145

Gene Ontology  (GO ID)

Biological Process

GO:0006281  DNA repair
GO:0009790  embryonic development
GO:0016567  protein ubiquitination
GO:0042787  protein ubiquitination during ubiquitin-dependent protein catabolic process
GO:0006974  response to DNA damage stimulus

Cellular Component

GO:0005575  cellular_component
GO:0005737  cytoplasm
GO:0005654  nucleoplasm
GO:0005634  nucleus

Molecular Function

GO:0005515  protein binding
GO:0046966  thyroid hormone receptor binding
GO:0004842  ubiquitin-protein ligase activity