myocardin

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Synonym

MYOCD, Myocardin, myocardin, MYCD

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:4.70 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:112.30 retina:- eye:5.90 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:25.60 skin:-
GeneChip nodata
CAGE cerebrum:0.45 cerebellum:- brain stem:0.59 corpus callosum/glia:0.55 pineal gland:0.71 peripheral nerve:- spine:0.48 retina:- eye:- artery/aorta:4.33 vein:2.79 lymphnode:0.15 peripheral blood:- spleen:0.25 thymus:0.12 bone marrow:- adipose:1.86 bone:- skin:-
RNA-seq cerebrum:0.13 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.29 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.00 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:18.20 prostate:67.60 ovary:37.30 testis:13 heart:63.90 muscle:- esophagus:- stomach:- intestine:- colon:17     liver/hepato:-        lung:24.40    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:8.90 breast:27.90 salivary:-
GeneChip nodata
CAGE uterus:3.70 placenta:1.53 prostate:3.62 ovary:3.11 testis:2.24 heart:3.51 muscle:1.32 esophagus:3.39 stomach:- intestine:2.61 colon:3.18     liver/hepato:0.14    lung:1.67 bladder:4.23 kidney:1.06 pituitary:0.56 thyroid/parathyroid:0.73 adrenal gland:- pancreas:0 breast:1.68 salivary:0.36
RNA-seq uterus:- placenta:- prostate:0.62 ovary:0.56 testis:0.67 heart:0.98 muscle:0.46 esophagus:- stomach:- intestine:- colon:1.18     liver/hepato:0.02        lung:0.00    bladder:- kidney:0.37 pituitary:- thyroid/parathyroid:0.24 adrenal gland:0.00 pancreas:- breast:0.20 salivary:-

Gene Information

IDs

Refseq ID NM_153604
Gene ID 93649
Unigene ID Hs.567641
Probe set ID -
Ensembl ID ENSG00000141052
GTEx ID ENSG00000141052

Orthologous Gene

Mouse[4]  NM_145136, NM_146386
Rat[1]  NM_182667, NM_146386

Chromosomal Region

17p12  [12,569,207  -  12,672,266]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

11439182
12397177
12477932
12640126
12756293
14702039
14970199
15014501
15907818
16054032
16141410
16151017
16224064
16344560
16625196
16818234
17215356
17292825
17360478
17430246
17579192
17620599
17938287
17940050
17991879
18028454
18451334
18772130
18852265
19098903
19156129
19237536
19276386
19342595
19776005
19797053
19801679
19883264
19952936
20068148
20379614
20385216
20458751
20560679
20848417
21051663
21506120
21984848
22075245
22666593
22675492
22843699
22850315
22937150
23175675
23342164
23671695
23704920
23861494
24060351
24344135

Gene Ontology  (GO ID)

Biological Process

GO:0035051  cardiac cell differentiation
GO:0055007  cardiac muscle cell differentiation
GO:0003231  cardiac ventricle development
GO:0043954  cellular component maintenance
GO:0071363  cellular response to growth factor stimulus
GO:0071456  cellular response to hypoxia
GO:0048565  gut development
GO:0048286  lung alveolus development
GO:0010667  negative regulation of cardiac muscle cell apoptosis
GO:0008285  negative regulation of cell proliferation
GO:0045736  negative regulation of cyclin-dependent protein kinase activity
GO:0010832  negative regulation of myotube differentiation
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0008284  positive regulation of cell proliferation
GO:0043388  positive regulation of DNA binding
GO:0051152  positive regulation of smooth muscle cell differentiation
GO:0045987  positive regulation of smooth muscle contraction
GO:0051091  positive regulation of transcription factor activity
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0003257  positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0030511  positive regulation of transforming growth factor beta receptor signaling pathway
GO:0001560  regulation of cell growth by extracellular stimulus
GO:0035065  regulation of histone acetylation
GO:0045661  regulation of myoblast differentiation
GO:0051150  regulation of smooth muscle cell differentiation
GO:0001666  response to hypoxia
GO:0051145  smooth muscle cell differentiation
GO:0060157  urinary bladder development
GO:0060065  uterus development
GO:0001570  vasculogenesis
GO:0055012  ventricular cardiac muscle cell differentiation

Cellular Component

GO:0005634  nucleus

Molecular Function

GO:0035035  histone acetyltransferase binding
GO:0042826  histone deacetylase binding
GO:0005515  protein binding
GO:0019904  protein domain specific binding
GO:0070412  R-SMAD binding
GO:0003713  transcription coactivator activity
GO:0008134  transcription factor binding