heart and neural crest derivatives expressed 2

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Synonym

MGC125304, Thing2, HAND2, FLJ16260, Hed, dHand, dHAND, DHAND2, MGC125303, heart and neural crest derivatives expressed 2, DHAND

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:- cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip cerebrum:4.24 cerebellum:4.51 brain stem:4.34 corpus callosum/glia:4.37 pineal gland:- peripheral nerve:4.07 spine:4.01 retina:- eye:- artery/aorta:4.63 vein:4.83 lymphnode:4.10 peripheral blood:- spleen:3.99 thymus:3.64 bone marrow:4.29 adipose:4.35 bone:- skin:4.44
CAGE cerebrum:0.09 cerebellum:- brain stem:0.03 corpus callosum/glia:0.79 pineal gland:1.18 peripheral nerve:- spine:0.22 retina:- eye:- artery/aorta:4.40 vein:2.44 lymphnode:1.25 peripheral blood:- spleen:1.86 thymus:0.18 bone marrow:- adipose:1.41 bone:- skin:-
RNA-seq cerebrum:0.02 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:1.26 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.27 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:54.70 placenta:18.20 prostate:- ovary:298.10 testis:- heart:12.80 muscle:- esophagus:- stomach:- intestine:32.40 colon:33.90     liver/hepato:-        lung:4.90    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:50.80 pancreas:17.80 breast:- salivary:-
GeneChip uterus:4.69 placenta:4.63 prostate:3.86 ovary:4.69 testis:3.75 heart:4.69 muscle:4.60 esophagus:4.32 stomach:4.30 intestine:4.64 colon:4.78 liver/hepato:4.19 lung:4.25 bladder:- kidney:4.25 pituitary:4 thyroid/parathyroid:3.94 adrenal gland:4.25 pancreas:4.61 breast:4.02 salivary:4.21
CAGE uterus:4.92 placenta:5.22 prostate:3.81 ovary:3.78 testis:2.59 heart:4.88 muscle:0.94 esophagus:3.98 stomach:- intestine:3.79 colon:4.94     liver/hepato:3.14    lung:0.48 bladder:4.39 kidney:0.08 pituitary:0 thyroid/parathyroid:1.79 adrenal gland:- pancreas:2.48 breast:2.83 salivary:1.28
RNA-seq uterus:- placenta:- prostate:4.45 ovary:3.01 testis:1.91 heart:3.82 muscle:0.06 esophagus:- stomach:- intestine:- colon:5.23     liver/hepato:1.83        lung:0.33    bladder:- kidney:0.08 pituitary:- thyroid/parathyroid:1.92 adrenal gland:0.30 pancreas:- breast:0.93 salivary:-

Gene Ontology  (GO ID)

Biological Process

GO:0007512  adult heart development
GO:0001525  angiogenesis
GO:0006915  apoptosis
GO:0003253  cardiac neural crest cell migration involved in outflow tract morphogenesis
GO:0003219  cardiac right ventricle formation
GO:0060536  cartilage morphogenesis
GO:0060982  coronary artery morphogenesis
GO:0042733  embryonic digit morphogenesis
GO:0007507  heart development
GO:0001947  heart looping
GO:0003007  heart morphogenesis
GO:0001701  in utero embryonic development
GO:0010463  mesenchymal cell proliferation
GO:0010667  negative regulation of cardiac muscle cell apoptosis
GO:0043392  negative regulation of DNA binding
GO:0045668  negative regulation of osteoblast differentiation
GO:0043433  negative regulation of transcription factor activity
GO:0014032  neural crest cell development
GO:0003357  noradrenergic neuron differentiation
GO:0042475  odontogenesis of dentine-containing tooth
GO:0060021  palate development
GO:0048935  peripheral nervous system neuron development
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0003266  regulation of second heart field cardioblast proliferation
GO:0006355  regulation of transcription, DNA-dependent
GO:0001967  suckling behavior
GO:0048485  sympathetic nervous system development
GO:0048538  thymus development
GO:0043586  tongue development

Cellular Component

GO:0000790  nuclear chromatin
GO:0043234  protein complex
GO:0005667  transcription factor complex

Molecular Function

GO:0003680  AT DNA binding
GO:0044212  DNA regulatory region binding
GO:0070888  E-box binding
GO:0005515  protein binding
GO:0046982  protein heterodimerization activity
GO:0042803  protein homodimerization activity
GO:0033613  transcription activator binding
GO:0003713  transcription coactivator activity
GO:0008134  transcription factor binding