eukaryotic translation initiation factor 4E family member 2

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Synonym

eIF4E type 3, mRNA cap-binding protein 4EHP, EIF4E2, 4EHP, eIF-4E type 3, EIF4EL3, eIF4E-like protein 4E-LP, Eukaryotic translation initiation factor 4E-like 3, Eukaryotic translation initiation factor 4E type 3, IF4e, mRNA cap-binding protein type 3, 4E-LP

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:152.90 cerebellum:125.90 brain stem:- corpus callosum/glia:116.60 pineal gland:148.30 peripheral nerve:30.70 spine:- retina:- eye:64.60 artery/aorta:30 vein:- lymphnode:182 peripheral blood:36.40 spleen:75.60 thymus:51.50 bone marrow:59 adipose:40.30 bone:76.80 skin:67.20
GeneChip cerebrum:5.85 cerebellum:6.12 brain stem:5.92 corpus callosum/glia:5.84 pineal gland:- peripheral nerve:6.20 spine:5.81 retina:- eye:- artery/aorta:6.68 vein:6.77 lymphnode:6.73 peripheral blood:- spleen:6.44 thymus:6.92 bone marrow:6.89 adipose:6.58 bone:- skin:7.17
CAGE cerebrum:4.44 cerebellum:- brain stem:4.28 corpus callosum/glia:4.10 pineal gland:5.02 peripheral nerve:- spine:4.65 retina:- eye:- artery/aorta:4.24 vein:3.75 lymphnode:4.11 peripheral blood:- spleen:4.12 thymus:3.89 bone marrow:- adipose:3.94 bone:- skin:-
RNA-seq cerebrum:3.32 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:4.00 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:4.34 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:82 placenta:76.50 prostate:67.60 ovary:74.50 testis:181.70 heart:89.40 muscle:140.60 esophagus:- stomach:106.20 intestine:32.40 colon:59.40     liver/hepato:116.10        lung:127.10    bladder:- kidney:166.40 pituitary:232 thyroid/parathyroid:- adrenal gland:- pancreas:80 breast:83.60 salivary:-
GeneChip uterus:7.24 placenta:7.51 prostate:6.94 ovary:7.02 testis:7.36 heart:6.48 muscle:7.26 esophagus:7.65 stomach:6.84 intestine:7.09 colon:7.50 liver/hepato:7.04 lung:6.85 bladder:- kidney:6.73 pituitary:5.98 thyroid/parathyroid:6.24 adrenal gland:6.47 pancreas:7.03 breast:6.77 salivary:6.70
CAGE uterus:4.18 placenta:4.37 prostate:3.87 ovary:3.74 testis:4.22 heart:4.09 muscle:4.83 esophagus:4.04 stomach:- intestine:4.33 colon:3.95     liver/hepato:4.35    lung:4.02 bladder:3.98 kidney:4.33 pituitary:4.38 thyroid/parathyroid:3.79 adrenal gland:- pancreas:4.16 breast:3.89 salivary:4.58
RNA-seq uterus:- placenta:- prostate:4.53 ovary:4.20 testis:4.65 heart:3.18 muscle:4.16 esophagus:- stomach:- intestine:- colon:4.63     liver/hepato:4.87        lung:4.27    bladder:- kidney:4.52 pituitary:- thyroid/parathyroid:4.58 adrenal gland:4.33 pancreas:- breast:4.19 salivary:-

Gene Information

IDs

Refseq ID NM_004846
Gene ID 9470
Unigene ID Hs.292026
Probe set ID 209393_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000135930
GTEx ID ENSG00000135930

Orthologous Gene

Mouse[6]  NM_001039169, NM_001039170, NM_023314
Rat[1]  NM_001108808, NM_001039170, NM_023314

Chromosomal Region

2q37.1  [233,414,762  -  233,448,354]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

9582349
9653160
11042152
12477932
14623119
14702039
15094042
15153109
15489334
16189514
16344560
17289916
17353931
17368478
17369309
17979178
19060904
19615732
20379614
20467438
20531386
21079520
21139048
21832049
21890473
22751931
23940030
23991149
24250222
24255178
24408918

Gene Ontology  (GO ID)

Biological Process

GO:0019221  cytokine-mediated signaling pathway
GO:0001701  in utero embryonic development
GO:0017148  negative regulation of translation

Cellular Component

GO:0005829  cytosol
GO:0005845  mRNA cap binding complex

Molecular Function

GO:0005515  protein binding
GO:0000339  RNA cap binding
GO:0008135  translation factor activity, nucleic acid binding
GO:0003743  translation initiation factor activity
GO:0031625  ubiquitin protein ligase binding