CD36 molecule (thrombospondin receptor)

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Synonym

CD36 molecule (thrombospondin receptor), CD36 antigen, Leukocyte differentiation antigen CD36, GPIV, Platelet glycoprotein IV, FAT, Glycoprotein IIIb, GP3B, PAS IV, SCARB3, PAS-4 protein, CD36, Thrombospondin receptor, Platelet collagen receptor, PASIV, GP4, Fatty acid translocase, GPIIIB, Platelet glycoprotein 4

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:29.60 cerebellum:25.20 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:245.40 spine:786.10 retina:- eye:11.80 artery/aorta:30 vein:66.60 lymphnode:- peripheral blood:437.20 spleen:1077.70 thymus:116 bone marrow:118.10 adipose:2258.70 bone:38.40 skin:100.80
GeneChip cerebrum:3.41 cerebellum:3.40 brain stem:3.38 corpus callosum/glia:3.72 pineal gland:- peripheral nerve:4.72 spine:3.57 retina:- eye:- artery/aorta:7.69 vein:6.59 lymphnode:4.89 peripheral blood:- spleen:8.50 thymus:4.88 bone marrow:8.21 adipose:10.86 bone:- skin:7.41
CAGE cerebrum:0.83 cerebellum:- brain stem:0.75 corpus callosum/glia:1.31 pineal gland:0.71 peripheral nerve:- spine:0.99 retina:- eye:- artery/aorta:3.64 vein:5.41 lymphnode:2.89 peripheral blood:- spleen:5.77 thymus:2.79 bone marrow:- adipose:8.20 bone:- skin:-
RNA-seq cerebrum:0.00 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:3.31 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:7.97 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:82 placenta:335.20 prostate:56.30 ovary:- testis:17.30 heart:1685.90 muscle:421.90 esophagus:685.60 stomach:63.70 intestine:356.40 colon:17     liver/hepato:200.60        lung:122.20    bladder:125.60 kidney:31.20 pituitary:- thyroid/parathyroid:- adrenal gland:253.90 pancreas:26.70 breast:92.90 salivary:-
GeneChip uterus:4.09 placenta:7.98 prostate:4.05 ovary:4.03 testis:3.58 heart:9.53 muscle:8.68 esophagus:4.92 stomach:5.84 intestine:6.93 colon:5.38 liver/hepato:5.94 lung:7.38 bladder:- kidney:3.68 pituitary:3.47 thyroid/parathyroid:6.25 adrenal gland:5.22 pancreas:5.64 breast:7.29 salivary:4.18
CAGE uterus:2.59 placenta:5.32 prostate:4.28 ovary:2.87 testis:3.02 heart:5.74 muscle:4.88 esophagus:4.03 stomach:- intestine:5.15 colon:4.50     liver/hepato:4.43    lung:4.60 bladder:4.26 kidney:2.70 pituitary:1.64 thyroid/parathyroid:4.22 adrenal gland:- pancreas:2.98 breast:7.10 salivary:3.03
RNA-seq uterus:- placenta:- prostate:2.39 ovary:0.00 testis:1.00 heart:7.98 muscle:0.83 esophagus:- stomach:- intestine:- colon:5.48     liver/hepato:0.00        lung:4.11    bladder:- kidney:0.18 pituitary:- thyroid/parathyroid:3.15 adrenal gland:1.31 pancreas:- breast:5.25 salivary:-

IDs

Refseq ID NM_001001547
Gene ID 948
Unigene ID Hs.120949
Probe set ID 209555_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000135218
GTEx ID ENSG00000135218

Orthologous Gene

Mouse[30]  NM_001159555, NM_001159556, NM_001159557, NM_001159558, NM_007643
Rat[5]  NM_031561, NM_001109218, NM_001159557, NM_001159558, NM_007643

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed  (Pubmed ID)

1384492
1715582
2468669
2468670
2473841
7503937
7505064
7518447
7521304
7533783
7682812
7686693
7693034
7693552
8467233
8561798
8696942
8798390
9171348
9334230
9555943
9568716
10391209
10487979
10772654
10772928
10772961
10890433
11238109
11377606
11433350
11602321
11668637
11686358
11714819
11718687
11834946
11867619
11872368
11950861
12023894
12031598
12105195
12164325
12169456
12224819
12376530
12477932
12479587
12496189
12506336
12516552
12576469
12598312
12606036
12618277
12664607
12679131
12690205
12716760
12716848
12732844
12801610
12947091
12968020
12971464
14684613
14699114
14702039
14719070
14729862
15048167
15050739
15059642
15064117
15132977
15167446
15221799
15242332
15282206
15339698
15342556
15478802
15489334
15671915
15677505
15735450
15780035
15860439
15897321
15915335
15933580
15978955
15979077
16002039
16037098
16099393
16219805
16263699
16276419
16299313
16344560
16453284
16502470
16515687
16556603
16622019
16645727
16670153
16670819
16838191
16870193
16880211
16887969
16908526
16911630
16952981
17067553
17071479
17084382
17311893
17346709
17380316
17412877
17416590
17440173
17496152
17572512
17573918
17581812
17619827
17673938
17710630
17716309
17854769
17888147
17900273
17905828
17924847
18000176
18029348
18035074
18053692
18067591
18263877
18285332
18288886
18299339
18305138
18353783
18441389
18458151
18462250
18497330
18514070
18550349
18558917
18582374
18660489
18671254
18827892
18844973
18981136
19016618
19055786
19065049
19088437
19116451
19136129
19144874
19156623
19175917
19185504
19190027
19203752
19350111
19369259
19403559
19413744
19454037
19489681
19578796
19640849
19667111
19718657
19740737
19864601
19865095
19876004
19893500
19913121
19948975
19996318
20015873
20023206
20037584
20075072
20113368
20139232
20157514
20223461
20333725
20408759
20408954
20414830
20416077
20459687
20485444
20628086
20629037
20637247
20660057
20664056
20684828
20701912
20722468
20935172
20939828
20946164
20947105
20966904
20966915
21091228
21145461
21155254
21203512
21228269
21250778
21262584
21270117
21346626
21378271
21383152
21390226
21437286
21454644
21462325
21478428
21547502
21696539
21727988
21808142
21832049
21835916
21854984
21890620
21949655
21988832
22047506
22050542
22075538
22106368
22113854
22240721
22247259
22275803
22423221
22430143
22558273
22588808
22653277
22687273
22763563
22795952
22869067
22890011
22909232
22993001
23119050
23206327
23213279
23233532
23249574
23383108
23427331
23603908
23656756
23726366
23748423
23792019
23817509
23844572
23856131
23862574
24009511
24062612
24069322
24090054
24120574
24130805
24145510
24284794
24366867
24371122
24412488
24503477
24675658

Gene Ontology  (GO ID)

Biological Process

GO:0042590  antigen processing and presentation of exogenous peptide antigen via MHC class I
GO:0002479  antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0002474  antigen processing and presentation of peptide antigen via MHC class I
GO:0043277  apoptotic cell clearance
GO:0007596  blood coagulation
GO:0007155  cell adhesion
GO:0007166  cell surface receptor linked signal transduction
GO:0044255  cellular lipid metabolic process
GO:0071221  cellular response to bacterial lipopeptide
GO:0071447  cellular response to hydroperoxide
GO:0071222  cellular response to lipopolysaccharide
GO:0071223  cellular response to lipoteichoic acid
GO:0019934  cGMP-mediated signaling
GO:0030301  cholesterol transport
GO:0050830  defense response to Gram-positive bacterium
GO:0045087  innate immune response
GO:0006629  lipid metabolic process
GO:0019915  lipid storage
GO:0034381  lipoprotein particle clearance
GO:0042953  lipoprotein transport
GO:0055096  low-density lipoprotein mediated signaling
GO:0034383  low-density lipoprotein particle clearance
GO:0002755  MyD88-dependent toll-like receptor signaling pathway
GO:0044130  negative regulation of growth of symbiont in host
GO:0042992  negative regulation of transcription factor import into nucleus
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0007263  nitric oxide mediated signal transduction
GO:0006910  phagocytosis, recognition
GO:0015911  plasma membrane long-chain fatty acid transport
GO:0030168  platelet activation
GO:0002576  platelet degranulation
GO:0030194  positive regulation of blood coagulation
GO:0001954  positive regulation of cell-matrix adhesion
GO:0010886  positive regulation of cholesterol storage
GO:0043123  positive regulation of I-kappaB kinase/NF-kappaB cascade
GO:0032735  positive regulation of interleukin-12 production
GO:0032755  positive regulation of interleukin-6 production
GO:0060907  positive regulation of macrophage cytokine production
GO:0010744  positive regulation of macrophage derived foam cell differentiation
GO:0043410  positive regulation of MAPKKK cascade
GO:0050731  positive regulation of peptidyl-tyrosine phosphorylation
GO:0060100  positive regulation of phagocytosis, engulfment
GO:0032760  positive regulation of tumor necrosis factor production
GO:0034134  toll-like receptor 2 signaling pathway
GO:0034142  toll-like receptor 4 signaling pathway
GO:0002224  toll-like receptor signaling pathway

Cellular Component

GO:0009986  cell surface
GO:0030666  endocytic vesicle membrane
GO:0009897  external side of plasma membrane
GO:0005794  Golgi apparatus
GO:0005887  integral to plasma membrane
GO:0016020  membrane
GO:0045121  membrane raft
GO:0045335  phagocytic vesicle
GO:0005886  plasma membrane
GO:0031092  platelet alpha granule membrane

Molecular Function

GO:0008035  high-density lipoprotein binding
GO:0008289  lipid binding
GO:0070892  lipoteichoic acid receptor activity
GO:0030169  low-density lipoprotein binding
GO:0005041  low-density lipoprotein receptor activity
GO:0070053  thrombospondin receptor activity
GO:0050431  transforming growth factor beta binding