Ctr9, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)

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Synonym

SH2 domain-binding protein 1, KIAA0155, p150TSP, TSBP, RNA polymerase-associated protein CTR9 homolog, SH2BP1, CTR9

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST nodata
GeneChip cerebrum:6.66 cerebellum:6.47 brain stem:6.67 corpus callosum/glia:6.83 pineal gland:- peripheral nerve:7.19 spine:6.78 retina:- eye:- artery/aorta:6.48 vein:5.90 lymphnode:7.45 peripheral blood:- spleen:7.49 thymus:8.05 bone marrow:6.88 adipose:7.10 bone:- skin:7.04
CAGE cerebrum:3.58 cerebellum:- brain stem:3.48 corpus callosum/glia:3.37 pineal gland:4.42 peripheral nerve:- spine:3.78 retina:- eye:- artery/aorta:3.27 vein:3.92 lymphnode:3.74 peripheral blood:- spleen:4.01 thymus:4.24 bone marrow:- adipose:3.65 bone:- skin:-
RNA-seq cerebrum:2.92 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:3.55 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:3.31 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST nodata
GeneChip uterus:7.87 placenta:7.49 prostate:7.79 ovary:7.88 testis:7.79 heart:6.90 muscle:7.10 esophagus:7.42 stomach:6.85 intestine:6.71 colon:5.83 liver/hepato:7.12 lung:7.03 bladder:- kidney:6.73 pituitary:7.48 thyroid/parathyroid:7.33 adrenal gland:7.31 pancreas:6.70 breast:7.09 salivary:6.71
CAGE uterus:3.78 placenta:3.96 prostate:3.69 ovary:3.99 testis:4.12 heart:3.72 muscle:3.81 esophagus:3.65 stomach:- intestine:3.71 colon:3.45     liver/hepato:4.13    lung:3.70 bladder:3.69 kidney:3.66 pituitary:4.24 thyroid/parathyroid:3.65 adrenal gland:- pancreas:3.23 breast:4.04 salivary:3.26
RNA-seq uterus:- placenta:- prostate:3.63 ovary:4.53 testis:4.95 heart:2.94 muscle:2.64 esophagus:- stomach:- intestine:- colon:3.33     liver/hepato:3.26        lung:2.46    bladder:- kidney:4.22 pituitary:- thyroid/parathyroid:4.04 adrenal gland:3.64 pancreas:- breast:3.50 salivary:-

Gene Information

IDs

Refseq ID NM_014633
Gene ID 9646
Unigene ID -
Probe set ID 202060_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000198730
GTEx ID ENSG00000198730

Orthologous Gene

Mouse[3]  NM_009431
Rat [0]  

Chromosomal Region

11p15.3  [10,772,534  -  10,801,290]

Gene Family (Interpro ID)

IPR019734  Tetratricopeptide repeat

Link to Pubmed  (Pubmed ID)

8590280
8636124
12421765
12477932
15231748
15302935
15489334
15632063
15923622
16024656
16307923
16964243
17081983
17911113
18469135
18551993
19136632
19345177
20178742
20305087
20541477
21139048
21406692
21726809
21890473
21906983
22053931
22082156
22405323
22451921
22532828
22797925
22863883
22939629
23000965
23593388
23667531
24163370
24816145

Gene Ontology  (GO ID)

Biological Process

GO:0071222  cellular response to lipopolysaccharide
GO:0001711  endodermal cell fate commitment
GO:0033523  histone H2B ubiquitination
GO:0010390  histone monoubiquitination
GO:0070102  interleukin-6-mediated signaling pathway
GO:0007259  JAK-STAT cascade
GO:0045638  negative regulation of myeloid cell differentiation
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0051571  positive regulation of histone H3-K4 methylation
GO:0032968  positive regulation of RNA elongation from RNA polymerase II promoter
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0019827  stem cell maintenance
GO:0006351  transcription, DNA-dependent
GO:0016055  Wnt receptor signaling pathway

Cellular Component

GO:0016593  Cdc73/Paf1 complex
GO:0016607  nuclear speck

Molecular Function

GO:0005515  protein binding
GO:0042169  SH2 domain binding