eukaryotic translation initiation factor 4A, isoform 3

Synonym

eIF4AIII, DEAD (Asp-Glu-Ala-Asp) box polypeptide 48, EIF4A3, MGC10862, KIAA0111, DEAD box protein 48, Probable ATP-dependent RNA helicase DDX48, eIF4A3, hNMP265, Nuclear matrix protein 265, Eukaryotic initiation factor 4A-like NUK-34, DDX48, NUK-34, hNMP 265

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:33.20

cerebellum:50.40

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:153.40

spine:112.30

retina:-

eye:52.90

artery/aorta:30

vein:133.30

lymphnode:252.80

peripheral blood:36.40

spleen:18.90

thymus:-

bone marrow:78.70

adipose:-

bone:64

skin:33.60

GeneChip

cerebrum:7.64

cerebellum:7.66

brain stem:7.54

corpus callosum/glia:7.80

pineal gland:-

peripheral nerve:8.16

spine:8.11

retina:-

eye:-

artery/aorta:8.53

vein:8.31

lymphnode:8.44

peripheral blood:-

spleen:8.12

thymus:8.81

bone marrow:8.38

adipose:8.47

bone:-

skin:8.85

CAGE

cerebrum:3.10

cerebellum:-

brain stem:2.92

corpus callosum/glia:3.13

pineal gland:3.39

peripheral nerve:-

spine:2.95

retina:-

eye:-

artery/aorta:3.50

vein:3.41

lymphnode:3.30

peripheral blood:-

spleen:3.45

thymus:3.55

bone marrow:-

adipose:3.33

bone:-

skin:-

RNA-seq

cerebrum:3.96

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:4.60

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:4.66

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:45.60

placenta:116.60

prostate:101.40

ovary:-

testis:69.20

heart:63.90

muscle:-

esophagus:685.60

stomach:127.50

intestine:129.60

colon:84.80

liver/hepato:31.70

lung:92.90

bladder:-

kidney:52

pituitary:-

thyroid/parathyroid:-

adrenal gland:203.10

pancreas:115.60

breast:139.40

salivary:-

GeneChip

uterus:8.62

placenta:9

prostate:8.88

ovary:8.91

testis:8.99

heart:7.84

muscle:7.72

esophagus:9.02

stomach:8.05

intestine:8.11

colon:8.44

liver/hepato:7.60

lung:8.44

bladder:-

kidney:8.12

pituitary:8.18

thyroid/parathyroid:8.25

adrenal gland:8.81

pancreas:7.81

breast:8.80

salivary:7.85

CAGE

uterus:3.50

placenta:3.86

prostate:3.56

ovary:3.86

testis:3.87

heart:3.48

muscle:3.12

esophagus:3.78

stomach:-

intestine:3.10

colon:3.35

liver/hepato:3.02

lung:3.25

bladder:3.63

kidney:3.40

pituitary:3.42

thyroid/parathyroid:3.47

adrenal gland:-

pancreas:3.10

breast:2.91

salivary:2.99

RNA-seq

uterus:-

placenta:-

prostate:4.93

ovary:5.46

testis:5.59

heart:3.47

muscle:3.70

esophagus:-

stomach:-

intestine:-

colon:4.67

liver/hepato:3.91

lung:5.04

bladder:-

kidney:5.21

pituitary:-

thyroid/parathyroid:5.27

adrenal gland:5.05

pancreas:-

breast:4.01

salivary:-

IDs

Refseq ID	NM_014740
Gene ID	9775
Unigene ID	Hs.389649
Probe set ID	201303_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000141543
GTEx ID	ENSG00000141543

Orthologous Gene

Mouse[2]	NM_138669
Rat[2]	NM_138669

Chromosomal Region

17q25.3 [78,109,013 - 78,120,982]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR014001	DEAD-like helicase, N-terminal
IPR014021	Helicase, superfamily 1/2, ATP-binding domain

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

GO:0019221	cytokine-mediated signaling pathway
GO:0010467	gene expression
GO:0016071	mRNA metabolic process
GO:0051028	mRNA transport
GO:0017148	negative regulation of translation
GO:0000398	nuclear mRNA splicing, via spliceosome
GO:0000288	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening
GO:0045727	positive regulation of translation
GO:0016070	RNA metabolic process
GO:0006364	rRNA processing

Cellular Component

GO:0071013	catalytic step 2 spliceosome
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0035145	exon-exon junction complex
GO:0016607	nuclear speck

Molecular Function

GO:0005524	ATP binding
GO:0004004	ATP-dependent RNA helicase activity
GO:0008143	poly(A) RNA binding
GO:0005515	protein binding

eukaryotic translation initiation factor 4A, isoform 3

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function