NUAK family, SNF1-like kinase, 1

 jump to detail

Synonym

NUAK1, NuaK1, NUAK family SNF1-like kinase 1, KIAA0537, AMPK-related protein kinase 5, ARK5, NUAK family, SNF1-like kinase, 1

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST nodata
GeneChip cerebrum:8.53 cerebellum:8.48 brain stem:8.06 corpus callosum/glia:8.20 pineal gland:- peripheral nerve:8.23 spine:7.63 retina:- eye:- artery/aorta:8.01 vein:7.02 lymphnode:6.12 peripheral blood:- spleen:5.11 thymus:5.76 bone marrow:5.31 adipose:7.73 bone:- skin:7.89
CAGE cerebrum:3.60 cerebellum:- brain stem:3.68 corpus callosum/glia:3.59 pineal gland:1.81 peripheral nerve:- spine:3.25 retina:- eye:- artery/aorta:3.54 vein:2.78 lymphnode:1.98 peripheral blood:- spleen:0.51 thymus:1.38 bone marrow:- adipose:3.70 bone:- skin:-
RNA-seq cerebrum:4.56 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:2.67 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:3.47 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST nodata
GeneChip uterus:7.33 placenta:6.67 prostate:7.04 ovary:7.20 testis:5.66 heart:7.93 muscle:7.53 esophagus:6.26 stomach:6.80 intestine:6.89 colon:6.59 liver/hepato:6.50 lung:7.74 bladder:- kidney:6.51 pituitary:6.77 thyroid/parathyroid:6.09 adrenal gland:6.79 pancreas:6.07 breast:7.77 salivary:5.54
CAGE uterus:3.63 placenta:2.26 prostate:2.79 ovary:2.90 testis:2.42 heart:3.68 muscle:3.38 esophagus:2.73 stomach:- intestine:1.55 colon:2.51     liver/hepato:2.08    lung:3.34 bladder:2.73 kidney:2.66 pituitary:2.79 thyroid/parathyroid:2.29 adrenal gland:- pancreas:1.21 breast:3.60 salivary:1.28
RNA-seq uterus:- placenta:- prostate:2.11 ovary:2.40 testis:2.20 heart:3.17 muscle:2.13 esophagus:- stomach:- intestine:- colon:2.69     liver/hepato:1.39        lung:2.20    bladder:- kidney:2.15 pituitary:- thyroid/parathyroid:2.26 adrenal gland:2.87 pancreas:- breast:3.50 salivary:-

Gene Information

IDs

Refseq ID NM_014840
Gene ID 9891
Unigene ID -
Probe set ID 204589_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000074590
GTEx ID ENSG00000074590

Orthologous Gene

Mouse[1]  NM_001004363
Rat[1]  NM_001106774

Chromosomal Region

12q23.3  [106,457,118  -  106,533,811]

Gene Family (Interpro ID)

IPR000719  Protein kinase, catalytic domain
IPR011009  Protein kinase-like domain
IPR002290  Serine/threonine-protein kinase domain
IPR017442  Serine/threonine-protein kinase-like domain
IPR001245  Tyrosine-protein kinase, catalytic domain
IPR020635  Tyrosine-protein kinase, subgroup, catalytic domain

Link to Pubmed  (Pubmed ID)

9628581
12409306
12477932
13679856
14702039
14976552
15060171
15273717
15354411
16044163
16306228
16488889
17353931
18254724
19322201
19927127
20354225
20602751
20978832
21317932
21750233
21832049
22105900
22460906
23063350
23080069
23215946
23419831
23516026
23934065
23940030
24785407

Gene Ontology  (GO ID)

Biological Process

GO:0007155  cell adhesion
GO:0030155  regulation of cell adhesion
GO:0042127  regulation of cell proliferation
GO:0006974  response to DNA damage stimulus

Cellular Component

GO:0005737  cytoplasm
GO:0005634  nucleus

Molecular Function

GO:0005524  ATP binding
GO:0046872  metal ion binding
GO:0002039  p53 binding
GO:0005515  protein binding
GO:0004674  protein serine/threonine kinase activity