SLIT-ROBO Rho GTPase activating protein 3

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Synonym

Mental disorder-associated GAP, srGAP2, SLIT-ROBO Rho GTPase-activating protein 3, WRP, WAVE-associated Rac GTPase-activating protein, MEGAP, ARHGAP14, SRGAP3, SLIT-ROBO Rho GTPase activating protein 3, Rho-GTPase-activating protein 14, SLIT-ROBO Rho GTPase activating protein 2, srGAP3, SRGAP2, KIAA0411

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST nodata
GeneChip cerebrum:7.88 cerebellum:9.14 brain stem:7.63 corpus callosum/glia:7.22 pineal gland:- peripheral nerve:7.42 spine:7.34 retina:- eye:- artery/aorta:5.97 vein:6.26 lymphnode:5.99 peripheral blood:- spleen:5.75 thymus:5.93 bone marrow:6.11 adipose:5.88 bone:- skin:6.13
CAGE cerebrum:4.00 cerebellum:- brain stem:3.79 corpus callosum/glia:3.92 pineal gland:2.76 peripheral nerve:- spine:3.26 retina:- eye:- artery/aorta:1.61 vein:1.89 lymphnode:1.99 peripheral blood:- spleen:0.88 thymus:1.70 bone marrow:- adipose:0.55 bone:- skin:-
RNA-seq cerebrum:1.05 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.66 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.00 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST nodata
GeneChip uterus:6.15 placenta:5.94 prostate:6.55 ovary:7.26 testis:6.34 heart:6.10 muscle:6.10 esophagus:5.87 stomach:5.99 intestine:6.01 colon:5.84 liver/hepato:6.12 lung:5.84 bladder:- kidney:6.49 pituitary:7.21 thyroid/parathyroid:6.39 adrenal gland:6.29 pancreas:5.62 breast:6.17 salivary:6.51
CAGE uterus:2.50 placenta:0.77 prostate:2.55 ovary:2.51 testis:2.43 heart:0.89 muscle:1.60 esophagus:1.92 stomach:- intestine:1.44 colon:1.14     liver/hepato:0.63    lung:1.49 bladder:1.84 kidney:1.82 pituitary:2.85 thyroid/parathyroid:1.72 adrenal gland:- pancreas:0.58 breast:1.36 salivary:3.49
RNA-seq uterus:- placenta:- prostate:1.37 ovary:1.52 testis:0.64 heart:0.56 muscle:0.00 esophagus:- stomach:- intestine:- colon:0.00     liver/hepato:0.07        lung:0.00    bladder:- kidney:0.84 pituitary:- thyroid/parathyroid:0.53 adrenal gland:0.77 pancreas:- breast:0.54 salivary:-

Gene Information

IDs

Refseq ID NM_014850
Gene ID 9901
Unigene ID -
Probe set ID 209794_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000196220
GTEx ID ENSG00000196220

Orthologous Gene

Mouse[2]  NM_080448
Rat [0]  

Chromosomal Region

3p25.3  [9,022,275  -  9,404,737]

Gene Family (Interpro ID)

IPR008936  Rho GTPase activation protein
IPR000198  RhoGAP

Link to Pubmed  (Pubmed ID)

8889548
9455477
10574461
11672528
12168954
12195014
12368262
12447388
12477932
12736724
14702039
16344560
16730001
17043677
17500595
19433673
19760623
19807924
20035503
20237496
20379614
20467438
23108406
23455924

Gene Ontology  (GO ID)

Biological Process

GO:0051056  regulation of small GTPase mediated signal transduction
GO:0007264  small GTPase mediated signal transduction

Cellular Component

GO:0005829  cytosol

Molecular Function

GO:0005096  GTPase activator activity