Rho-type GTPase-activating protein RICH2

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Synonym

KIAA0672 gene product, KIAA0672

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:78.20 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:224.60 retina:237.30 eye:41.10 artery/aorta:- vein:- lymphnode:40.40 peripheral blood:- spleen:- thymus:- bone marrow:19.70 adipose:- bone:12.80 skin:14.40
GeneChip cerebrum:6.90 cerebellum:7.26 brain stem:6.84 corpus callosum/glia:4.95 pineal gland:- peripheral nerve:5.91 spine:5.61 retina:- eye:- artery/aorta:5.36 vein:5.13 lymphnode:4.58 peripheral blood:- spleen:4.24 thymus:4.35 bone marrow:4.28 adipose:4.59 bone:- skin:4.24
CAGE cerebrum:3.48 cerebellum:- brain stem:2.48 corpus callosum/glia:2.26 pineal gland:1.66 peripheral nerve:- spine:2.12 retina:- eye:- artery/aorta:2.36 vein:1.61 lymphnode:0.98 peripheral blood:- spleen:0.88 thymus:0.74 bone marrow:- adipose:1.41 bone:- skin:-
RNA-seq cerebrum:3.93 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:1.90 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.94 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:27.30 placenta:25.50 prostate:- ovary:37.30 testis:26 heart:- muscle:20.10 esophagus:- stomach:- intestine:- colon:67.80     liver/hepato:-        lung:58.70    bladder:- kidney:20.80 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:17.80 breast:46.50 salivary:-
GeneChip uterus:5.12 placenta:5.03 prostate:5.28 ovary:6.14 testis:4.73 heart:5.39 muscle:4.48 esophagus:4.63 stomach:5.10 intestine:5.44 colon:6.42 liver/hepato:4.53 lung:6.30 bladder:- kidney:5.04 pituitary:6.40 thyroid/parathyroid:5.99 adrenal gland:4.55 pancreas:4.88 breast:4.78 salivary:5.72
CAGE uterus:2.12 placenta:1.80 prostate:2.25 ovary:2.08 testis:1.96 heart:1.85 muscle:1.21 esophagus:1.34 stomach:- intestine:2.63 colon:3.25     liver/hepato:0.14    lung:2.95 bladder:1.40 kidney:1.40 pituitary:3.27 thyroid/parathyroid:2.99 adrenal gland:- pancreas:2.18 breast:1.80 salivary:2.35
RNA-seq uterus:- placenta:- prostate:2.02 ovary:2.38 testis:2.36 heart:1.58 muscle:0.58 esophagus:- stomach:- intestine:- colon:1.81     liver/hepato:0.42        lung:3.04    bladder:- kidney:1.48 pituitary:- thyroid/parathyroid:2.64 adrenal gland:1.35 pancreas:- breast:1.05 salivary:-

Gene Information

IDs

Refseq ID NM_014859
Gene ID 9912
Unigene ID Hs.499758
Probe set ID 205414_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000006740
GTEx ID ENSG00000006740

Orthologous Gene

Mouse[2]  NM_001099288, NM_175003
Rat[2]  NM_001099288, NM_175003

Chromosomal Region

17p12  [12,692,829  -  12,894,960]

Gene Family (Interpro ID)

IPR008936  Rho GTPase activation protein
IPR000198  RhoGAP

Link to Pubmed  (Pubmed ID)

9734811
11431473
12477932
14702039
15489334
16169070
16344560
19273615
21107268
22566634
23648065
24250222
24816145

Gene Ontology  (GO ID)

Biological Process

GO:0051056  regulation of small GTPase mediated signal transduction
GO:0007264  small GTPase mediated signal transduction

Cellular Component

GO:0005829  cytosol

Molecular Function

GO:0005096  GTPase activator activity
GO:0005515  protein binding