cadherin 1, type 1, E-cadherin (epithelial)

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Synonym

cadherin 1, type 1, E-cadherin (epithelial), E-cadherin, CDHE, Arc-1, Uvomorulin, UVO, Cadherin-1, CD324, uvomorulin, CDH1, ECAD, CD324 antigen, Epithelial-cadherin precursor, CAM 120/80, LCAM

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:22.50 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:92 spine:- retina:- eye:29.40 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:18.90 thymus:25.80 bone marrow:19.70 adipose:- bone:12.80 skin:254.40
GeneChip cerebrum:3.35 cerebellum:3.38 brain stem:3.33 corpus callosum/glia:3.41 pineal gland:- peripheral nerve:3.92 spine:3.30 retina:- eye:- artery/aorta:3.54 vein:3.46 lymphnode:3.46 peripheral blood:- spleen:3.19 thymus:3.49 bone marrow:3.58 adipose:3.61 bone:- skin:4.09
CAGE cerebrum:1.45 cerebellum:- brain stem:1.81 corpus callosum/glia:2.35 pineal gland:0.57 peripheral nerve:- spine:1.86 retina:- eye:- artery/aorta:3.28 vein:2.75 lymphnode:3.22 peripheral blood:- spleen:2.44 thymus:3.89 bone marrow:- adipose:0.78 bone:- skin:-
RNA-seq cerebrum:0.93 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:1.01 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.36 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:54.70 placenta:120.20 prostate:101.40 ovary:74.50 testis:4.30 heart:63.90 muscle:20.10 esophagus:- stomach:531.10 intestine:97.20 colon:542.70     liver/hepato:95        lung:171.10    bladder:- kidney:52 pituitary:- thyroid/parathyroid:655 adrenal gland:- pancreas:71.10 breast:901.40 salivary:-
GeneChip uterus:3.72 placenta:4.61 prostate:5.72 ovary:4.12 testis:3.19 heart:3.33 muscle:3.64 esophagus:5.08 stomach:4.09 intestine:4.44 colon:5.24 liver/hepato:3.66 lung:3.55 bladder:- kidney:3.77 pituitary:3.84 thyroid/parathyroid:4.91 adrenal gland:3.24 pancreas:5.43 breast:3.99 salivary:4.11
CAGE uterus:3.81 placenta:5.51 prostate:5.01 ovary:3.36 testis:1.97 heart:0.25 muscle:0.42 esophagus:5.39 stomach:- intestine:6.38 colon:5.77     liver/hepato:5.59    lung:4.82 bladder:4.02 kidney:4.74 pituitary:4.39 thyroid/parathyroid:5.92 adrenal gland:- pancreas:5.75 breast:4.35 salivary:5.87
RNA-seq uterus:- placenta:- prostate:4.35 ovary:3.37 testis:2.64 heart:0 muscle:0.00 esophagus:- stomach:- intestine:- colon:4.09     liver/hepato:4.31        lung:4.11    bladder:- kidney:4.83 pituitary:- thyroid/parathyroid:6.65 adrenal gland:1.52 pancreas:- breast:3.99 salivary:-

IDs

Refseq ID NM_004360
Gene ID 999
Unigene ID Hs.461086
Probe set ID 201130_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000039068
GTEx ID ENSG00000039068

Orthologous Gene

Mouse[1]  NM_009864
Rat[1]  NM_031334

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed  (Pubmed ID)

1606546
1639850
2224804
2349235
3263290
7542250
7543680
7559781
7601454
7642713
7651399
7806582
7824937
7876318
7890674
7954478
7961105
8033105
8074697
8075649
8093045
8127895
8185635
8207061
8227214
8459805
8549695
8557030
8797891
8985087
9045944
9130654
9214391
9219219
9233779
9405455
9512503
9531566
9535896
9537325
9615235
9632747
9721589
9734353
9744472
9751616
9819408
9925936
9971746
10072428
10202138
10225956
10319582
10381631
10409703
10460003
10462524
10477433
10500174
10523846
10597309
10608854
10629228
10635315
10652321
10671552
10698519
10713718
10744074
10772923
10790430
10837471
10868478
10896919
10910767
10931041
10950951
10959047
10963665
10969083
11035789
11058098
11076937
11080149
11104024
11113628
11136230
11158177
11179419
11226248
11245482
11254878
11274246
11348595
11401320
11419427
11443625
11459826
11562785
11683173
11705864
11712088
11733362
11747475
11790800
11801604
11813884
11821434
11836526
11839665
11846558
11856755
11857408
11861761
11870667
11882288
11896626
11912130
11916976
11920500
11937138
11948460
11953314
11960376
11968083
11996968
12021924
12027444
12036913
12037667
12049819
12057916
12061792
12082610
12095414
12115723
12127160
12134161
12138162
12140137
12161443
12169098
12189238
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12203775
12209606
12209998
12216071
12219004
12234927
12370292
12391156
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12397640
12398810
12409468
12414996
12427869
12434297
12444556
12452045
12477932
12481018
12511569
12517779
12526809
12531901
12532418
12532420
12532436
12532469
12560341
12579297
12587534
12588804
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12615965
12629411
12634428
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14750169
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19741544
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19751508
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19802010
19802011
19822757
19823035
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19894558
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20156840
20173740
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20356845
20357201
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Gene Ontology  (GO ID)

Biological Process

GO:0034332  adherens junction organization
GO:0006915  apoptosis
GO:0034329  cell junction assembly
GO:0006921  cell structure disassembly during apoptosis
GO:0016337  cell-cell adhesion
GO:0045216  cell-cell junction organization
GO:0071230  cellular response to amino acid stimulus
GO:0071285  cellular response to lithium ion
GO:0090102  cochlea development
GO:0007156  homophilic cell adhesion
GO:0022408  negative regulation of cell-cell adhesion
GO:0031175  neuron projection development
GO:0021983  pituitary gland development
GO:0042993  positive regulation of transcription factor import into nucleus
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0051260  protein homooligomerization
GO:0019538  protein metabolic process
GO:0060693  regulation of branching involved in salivary gland morphogenesis
GO:0043281  regulation of caspase activity
GO:0050776  regulation of immune response
GO:0033561  regulation of water loss via skin
GO:0042493  response to drug
GO:0009636  response to toxin
GO:0060662  salivary gland cavitation
GO:0007605  sensory perception of sound
GO:0007416  synapse assembly
GO:0070830  tight junction assembly
GO:0001829  trophectodermal cell differentiation

Cellular Component

GO:0015629  actin cytoskeleton
GO:0016235  aggresome
GO:0043296  apical junction complex
GO:0045177  apical part of cell
GO:0016323  basolateral plasma membrane
GO:0016342  catenin complex
GO:0030054  cell junction
GO:0009986  cell surface
GO:0005913  cell-cell adherens junction
GO:0005737  cytoplasm
GO:0005768  endosome
GO:0005925  focal adhesion
GO:0005794  Golgi apparatus
GO:0016021  integral to membrane
GO:0009898  internal side of plasma membrane
GO:0043219  lateral loop
GO:0016328  lateral plasma membrane
GO:0043679  nerve terminal
GO:0033268  node of Ranvier
GO:0048471  perinuclear region of cytoplasm
GO:0005886  plasma membrane
GO:0043220  Schmidt-Lanterman cleft
GO:0005802  trans-Golgi network

Molecular Function

GO:0030506  ankyrin binding
GO:0008013  beta-catenin binding
GO:0005509  calcium ion binding
GO:0050839  cell adhesion molecule binding
GO:0045295  gamma-catenin binding
GO:0032794  GTPase activating protein binding
GO:0005515  protein binding
GO:0019904  protein domain specific binding
GO:0019903  protein phosphatase binding