SCO cytochrome oxidase deficient homolog 2 (yeast)

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Synonym

MGC125823, SCO1L, MGC125825, SCO2 protein homolog, mitochondrial precursor, SCO2, SCO cytochrome oxidase deficient homolog 2 (yeast)

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST nodata
GeneChip cerebrum:5.89 cerebellum:5.88 brain stem:5.83 corpus callosum/glia:5.85 pineal gland:- peripheral nerve:6.12 spine:6.06 retina:- eye:- artery/aorta:6.81 vein:6.75 lymphnode:7.89 peripheral blood:- spleen:7.07 thymus:6.91 bone marrow:6.80 adipose:7.31 bone:- skin:7.36
CAGE cerebrum:1.69 cerebellum:- brain stem:1.58 corpus callosum/glia:1.25 pineal gland:1.18 peripheral nerve:- spine:1.33 retina:- eye:- artery/aorta:1.57 vein:2.27 lymphnode:2.50 peripheral blood:- spleen:2.30 thymus:2.46 bone marrow:- adipose:2.01 bone:- skin:-
RNA-seq cerebrum:0.65 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:2.75 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:1.28 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST nodata
GeneChip uterus:6.06 placenta:6.48 prostate:6.10 ovary:6 testis:5.85 heart:6.40 muscle:6.08 esophagus:7.14 stomach:6.38 intestine:6.63 colon:6.60 liver/hepato:7.30 lung:7.72 bladder:- kidney:6.13 pituitary:6.40 thyroid/parathyroid:6.51 adrenal gland:6.31 pancreas:6.31 breast:6.53 salivary:6.43
CAGE uterus:1.84 placenta:1.73 prostate:1.87 ovary:1.71 testis:1.79 heart:2.10 muscle:1.50 esophagus:2.70 stomach:- intestine:2.56 colon:2.89     liver/hepato:2.73    lung:2.33 bladder:1.66 kidney:2.57 pituitary:1.36 thyroid/parathyroid:2.01 adrenal gland:- pancreas:2.26 breast:2.64 salivary:2.57
RNA-seq uterus:- placenta:- prostate:0.47 ovary:0.82 testis:1.19 heart:1.70 muscle:0.63 esophagus:- stomach:- intestine:- colon:0.99     liver/hepato:3.16        lung:1.88    bladder:- kidney:2.40 pituitary:- thyroid/parathyroid:0.91 adrenal gland:1.41 pancreas:- breast:2.56 salivary:-

Gene Information

IDs

Refseq ID NM_005138
Gene ID 9997
Unigene ID -
Probe set ID 204858_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000130489
GTEx ID ENSG00000130489

Orthologous Gene

Mouse[1]  NM_001111288
Rat[1]  NM_001111288

Chromosomal Region

22q13.33  [50,961,997  -  50,964,868]

Gene Family (Interpro ID)

IPR003782  Copper chaperone SCO1/SenC
IPR017276  Synthesis of cytochrome c oxidase, Sco1/Sco2

Link to Pubmed  (Pubmed ID)

10218584
10493829
10545952
10749987
11673586
11751685
11931660
12020273
12477932
12529303
12538779
14994243
15146197
15229189
15461802
15489334
16083427
16091356
16341674
16728594
17189203
17850752
18254779
18332255
18924171
19336478
19353431
19879173
19913121
20139978
20193760
20628086
20864674
21139048
21145461
21150319
21820150
21832049
21833088
21890473
21925769
21963094
22120717
22939629
23222517
23319048
23364397
23455922
23612020
23643385
23786650
24250222

Gene Ontology  (GO ID)

Biological Process

GO:0006878  cellular copper ion homeostasis
GO:0006825  copper ion transport
GO:0001701  in utero embryonic development
GO:0003012  muscle system process
GO:0055114  oxidation reduction
GO:0008535  respiratory chain complex IV assembly
GO:0022904  respiratory electron transport chain
GO:0014823  response to activity

Cellular Component

GO:0005743  mitochondrial inner membrane
GO:0005739  mitochondrion

Molecular Function

GO:0005507  copper ion binding