dedicator of cytokinesis 9

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Synonym

AW538057, dedicator of cytokinesis 9, Kiaa1058, Cdc42 guanine nucleotide exchange factor zizimin 1, B230309H04Rik, mKIAA1058, AA959601, D14Wsu89e, Dedicator of cytokinesis protein 9, Zizimin1, Dock9

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:53.80 cerebellum:36.80 brain stem:190.70 corpus callosum/glia:- pineal gland:- peripheral nerve:19.10 spine:- retina:32.10 eye:30.40 artery/aorta:- vein:- lymphnode:- peripheral blood:129.40 spleen:79 thymus:39.50 bone marrow:25.60 adipose:- bone:- skin:15.80
GeneChip cerebrum:10.05 cerebellum:11.17 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:10.12 spine:10.66 retina:9.94 eye:9.18 artery/aorta:- vein:9.65 lymphnode:9.97 peripheral blood:- spleen:7.94 thymus:- bone marrow:7.22 adipose:10.20 bone:8.61 skin:10.79
CAGE cerebrum:4.58 cerebellum:- brain stem:4.41 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:4.68 retina:- eye:- artery/aorta:4.52 vein:- lymphnode:3.59 peripheral blood:- spleen:1.52 thymus:1.99 bone marrow:- adipose:- bone:1.69 skin:4.01
RNA-seq cerebrum:6.48 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:43.60 placenta:55.20 prostate:- ovary:114.90 testis:29.60 heart:- muscle:71 esophagus:- stomach:- intestine:- colon:17.60     liver/hepato:-        lung:80.30    bladder:132.40 kidney:32.20 pituitary:- thyroid/parathyroid:112.50 adrenal gland:- pancreas:18.80 breast:143.70 salivary:-
GeneChip uterus:9.42 placenta:10.37 prostate:9.40 ovary:10.36 testis:7.13 heart:9.54 muscle:9.33 esophagus:- stomach:8.87 intestine:8.54 colon:- liver/hepato:8.04 lung:11.38 bladder:10.17 kidney:10.01 pituitary:8.96 thyroid/parathyroid:- adrenal gland:10.11 pancreas:9.19 breast:10.01 salivary:9.58
CAGE uterus:3.53 placenta:4.00 prostate:2.99 ovary:3.95 testis:1.34 heart:- muscle:- esophagus:- stomach:1.91 intestine:1.96 colon:2.46     liver/hepato:2.58    lung:4.80 bladder:3.84 kidney:- pituitary:3.00 thyroid/parathyroid:- adrenal gland:3.19 pancreas:3.21 breast:3.48 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:2.53 esophagus:- stomach:- intestine:- colon:-     liver/hepato:3.15        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_001081039
Gene ID 105445
Unigene ID Mm.441054
Probe set ID 1444028_s_at  [Mouse430_2]
Ensembl ID ENSMUSG00000025558

Orthologous Gene

Human[12]  NM_001130048, NM_001130049, NM_001130050, NM_015296
Rat[1]  NM_001105759, NM_001130049, NM_001130050, NM_015296

Chromosomal Region

14E5  [121,941,261  -  122,196,956]

Gene Family (Interpro ID)

IPR001849  Pleckstrin homology

Link to Pubmed  (Pubmed ID)

8889548
9811942
10349636
10725249
10922068
11042159
11076861
11217851
12466851
12477932
12520002
12693553
14610273
15489334
15710388
15741177
16141072
16141073
17114649
19156867
22987639

Gene Ontology  (GO ID)

Biological Process

GO:0050790  regulation of catalytic activity
GO:0007264  small GTPase mediated signal transduction

Cellular Component

GO:0005575  cellular_component
GO:0016020  membrane

Molecular Function

GO:0005085  guanyl-nucleotide exchange factor activity
GO:0005543  phospholipid binding
GO:0017048  Rho GTPase binding
GO:0005089  Rho guanyl-nucleotide exchange factor activity