arrestin, beta 1

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Synonym

Arrestin beta 1, Beta-arrestin-1, MGC124270, 1200006I17Rik, arrestin, beta 1, Arrb1, AW208571, MGC124269, G430100A01Rik

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:234.40 cerebellum:73.70 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:477.70 spine:94.60 retina:96.40 eye:83.60 artery/aorta:- vein:- lymphnode:820.90 peripheral blood:43.10 spleen:434.50 thymus:19.80 bone marrow:- adipose:- bone:62.60 skin:7.90
GeneChip cerebrum:9.26 cerebellum:8.91 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:9.39 spine:9.12 retina:6.62 eye:5.94 artery/aorta:- vein:6.16 lymphnode:8.29 peripheral blood:- spleen:8.42 thymus:- bone marrow:9.98 adipose:7.29 bone:9.59 skin:7.83
CAGE cerebrum:4.17 cerebellum:- brain stem:4.34 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:4.26 retina:- eye:- artery/aorta:3.37 vein:- lymphnode:3.84 peripheral blood:- spleen:5.13 thymus:2.46 bone marrow:- adipose:- bone:4.67 skin:3.60
RNA-seq cerebrum:17.49 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:262.30 prostate:- ovary:- testis:7.40 heart:- muscle:- esophagus:- stomach:- intestine:- colon:17.60     liver/hepato:45.30        lung:90.40    bladder:66.20 kidney:72.50 pituitary:77.50 thyroid/parathyroid:112.50 adrenal gland:- pancreas:- breast:101.20 salivary:162
GeneChip uterus:8.07 placenta:8.19 prostate:8.07 ovary:7.74 testis:5.84 heart:6.28 muscle:6.57 esophagus:- stomach:7.99 intestine:8.41 colon:- liver/hepato:5.91 lung:9.45 bladder:7.44 kidney:7.33 pituitary:5.79 thyroid/parathyroid:- adrenal gland:7.50 pancreas:6.63 breast:8 salivary:7.82
CAGE uterus:3.27 placenta:3.79 prostate:3.56 ovary:3.34 testis:2.19 heart:- muscle:- esophagus:- stomach:3.05 intestine:3.66 colon:3.76     liver/hepato:2.06    lung:4.41 bladder:3.53 kidney:- pituitary:2.35 thyroid/parathyroid:- adrenal gland:3.27 pancreas:3.53 breast:3.33 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:1.81 esophagus:- stomach:- intestine:- colon:-     liver/hepato:2.04        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_177231
Gene ID 109689
Unigene ID Mm.260193
Probe set ID 1460444_at  [Mouse430_2]
Ensembl ID ENSMUSG00000018909

Orthologous Gene

Human[4]  NM_004041, NM_020251
Rat [0]  

Chromosomal Region

7E2  [106,683,976  -  106,755,281]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

1458825
7613043
7932878
8321239
8889548
9054939
9073507
9333241
9400383
10349636
10508404
10549660
10704496
11042159
11076861
11171997
11217851
11468275
11546805
11579203
11687607
11853756
12167719
12393857
12466851
12477932
12509508
12716919
12821670
12975449
14534298
15102471
15308653
15489334
15541899
15878855
16141072
16141073
16183993
16219764
16263766
16299272
16325578
16378096
16421323
16436601
17060617
17108167
17194706
17360618
17418896
17426148
17442737
17460248
17525124
17594911
17618287
17664271
17666399
17680774
17881515
17890288
18055791
18276584
18287559
18425122
18497258
18519945
18701071
18775329
18799693
18953287
19074139
19349687
19361994
19531493
19587094
19776273
19896992
19915011
20060823
20203204
20207744
20412604
20421423
20530803
20589830
20855896
20935513
20959465
21139074
21233215
21267068
21283538
21369867
21411739
21543334
21630325
21677750
21700709
21757712
21824517
21855149
21857681
22025682
22034973
22308427
22315403
22318609
22465333
22699970
22773819
23166351
23208420
23235155
23287463
23395087
23449980
23557604
23582260
23589893
24218435
24239352
24334028
24371298
24502978
24692549

Gene Ontology  (GO ID)

Biological Process

GO:0000187  activation of MAPK activity
GO:0006309  DNA fragmentation involved in apoptosis
GO:0006897  endocytosis
GO:0042699  follicle-stimulating hormone signaling pathway
GO:0002031  G-protein coupled receptor internalization
GO:0007186  G-protein coupled receptor protein signaling pathway
GO:0043066  negative regulation of apoptosis
GO:0043154  negative regulation of caspase activity
GO:0070373  negative regulation of ERK1 and ERK2 cascade
GO:0034260  negative regulation of GTPase activity
GO:0032715  negative regulation of interleukin-6 production
GO:0032717  negative regulation of interleukin-8 production
GO:0032088  negative regulation of NF-kappaB transcription factor activity
GO:0001933  negative regulation of protein amino acid phosphorylation
GO:0031397  negative regulation of protein ubiquitination
GO:0009968  negative regulation of signal transduction
GO:0007602  phototransduction
GO:0070374  positive regulation of ERK1 and ERK2 cascade
GO:0043547  positive regulation of GTPase activity
GO:0035066  positive regulation of histone acetylation
GO:0033138  positive regulation of peptidyl-serine phosphorylation
GO:0032092  positive regulation of protein binding
GO:0031398  positive regulation of protein ubiquitination
GO:0035025  positive regulation of Rho protein signal transduction
GO:0034393  positive regulation of smooth muscle cell apoptosis
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0043161  proteasomal ubiquitin-dependent protein catabolic process
GO:0015031  protein transport
GO:0016567  protein ubiquitination
GO:0008277  regulation of G-protein coupled receptor protein signaling pathway
GO:0006355  regulation of transcription, DNA-dependent
GO:0007165  signal transduction
GO:0043149  stress fiber formation
GO:0006366  transcription from RNA polymerase II promoter
GO:0006351  transcription, DNA-dependent
GO:0006810  transport

Cellular Component

GO:0016323  basolateral plasma membrane
GO:0042995  cell projection
GO:0000785  chromatin
GO:0005905  coated pit
GO:0005737  cytoplasm
GO:0031410  cytoplasmic vesicle
GO:0005829  cytosol
GO:0043197  dendritic spine
GO:0005622  intracellular
GO:0016020  membrane
GO:0005634  nucleus
GO:0005886  plasma membrane
GO:0014069  postsynaptic density
GO:0045211  postsynaptic membrane
GO:0031143  pseudopodium

Molecular Function

GO:0031691  alpha-1A adrenergic receptor binding
GO:0031692  alpha-1B adrenergic receptor binding
GO:0031701  angiotensin receptor binding
GO:0043027  caspase inhibitor activity
GO:0044212  DNA regulatory region binding
GO:0030331  estrogen receptor binding
GO:0031762  follicle stimulating hormone receptor binding
GO:0005096  GTPase activator activity
GO:0005159  insulin-like growth factor receptor binding
GO:0031434  mitogen-activated protein kinase kinase binding
GO:0051219  phosphoprotein binding
GO:0005515  protein binding
GO:0045309  protein phosphorylated amino acid binding
GO:0008134  transcription factor binding
GO:0031625  ubiquitin protein ligase binding
GO:0031896  V2 vasopressin receptor binding