argininosuccinate lyase

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Synonym

Asl, 2510006M18Rik, ASAL, argininosuccinate lyase, Arginosuccinase, Argininosuccinate lyase

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST nodata
GeneChip cerebrum:6.82 cerebellum:6.58 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:7.77 spine:7.03 retina:6.91 eye:7.66 artery/aorta:- vein:6.91 lymphnode:7.97 peripheral blood:- spleen:7.24 thymus:- bone marrow:7.30 adipose:8.32 bone:6.96 skin:6.03
CAGE cerebrum:2.06 cerebellum:- brain stem:2.51 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:2.57 retina:- eye:- artery/aorta:2.19 vein:- lymphnode:2.31 peripheral blood:- spleen:1.60 thymus:1.75 bone marrow:- adipose:- bone:2.37 skin:2.28
RNA-seq cerebrum:8.72 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST nodata
GeneChip uterus:8.11 placenta:8.15 prostate:10.07 ovary:8.14 testis:7.45 heart:6.11 muscle:6.50 esophagus:- stomach:7.65 intestine:7.94 colon:- liver/hepato:12.07 lung:7.81 bladder:7.31 kidney:10.71 pituitary:6.73 thyroid/parathyroid:- adrenal gland:8.88 pancreas:7.51 breast:7.70 salivary:8.16
CAGE uterus:2.64 placenta:2.66 prostate:3.08 ovary:2.42 testis:1.80 heart:- muscle:- esophagus:- stomach:2.16 intestine:2.69 colon:2.60     liver/hepato:6.19    lung:2.38 bladder:2.44 kidney:- pituitary:2.56 thyroid/parathyroid:- adrenal gland:3.13 pancreas:2.90 breast:2.63 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:3.20 esophagus:- stomach:- intestine:- colon:-     liver/hepato:115.23        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_133768
Gene ID 109900
Unigene ID -
Probe set ID 1448350_at  [Mouse430_2]
Ensembl ID ENSMUSG00000025533

Orthologous Gene

Human[4]  NM_000048, NM_001024943, NM_001024944, NM_001024946
Rat [0]  

Chromosomal Region

-

Gene Family (Interpro ID)

IPR009049  Argininosuccinate lyase
IPR003031  Delta crystallin
IPR000362  Fumarate lyase
IPR008948  L-Aspartase-like

Link to Pubmed  (Pubmed ID)

2644168
7504460
8889548
9337408
9878248
10198163
10349636
10575226
10922068
11013070
11042159
11076861
11092456
11217851
11352562
12466851
12477932
12559843
14681479
15472464
15489334
15782199
16141072
16141073
17933574
21267068
22081021
22541557

Gene Ontology  (GO ID)

Biological Process

GO:0019676  ammonia assimilation cycle
GO:0006526  arginine biosynthetic process
GO:0042450  arginine biosynthetic process via ornithine
GO:0000053  argininosuccinate metabolic process
GO:0008652  cellular amino acid biosynthetic process
GO:0006520  cellular amino acid metabolic process
GO:0006475  internal protein amino acid acetylation
GO:0001889  liver development
GO:0007626  locomotory behavior
GO:0009791  post-embryonic development
GO:0000050  urea cycle

Cellular Component

GO:0070852  cell body fiber
GO:0043025  cell soma
GO:0005737  cytoplasm
GO:0005783  endoplasmic reticulum
GO:0005741  mitochondrial outer membrane
GO:0005634  nucleus
GO:0043204  perikaryon
GO:0048471  perinuclear region of cytoplasm

Molecular Function

GO:0004056  argininosuccinate lyase activity
GO:0003824  catalytic activity
GO:0016829  lyase activity