EGL nine homolog 1 (C. elegans)

Synonym

AI503754, ORF13, HIF-prolyl hydroxylase 2, HIF-PH2, Hypoxia-inducible factor prolyl hydroxylase 2, Egl nine homolog 1, Egln1, C1orf12, EGL nine homolog 1 (C. elegans), HPH-2

normal 40 tissues
developmental tissues and primary cells（FANTOM5 CAGE）

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:74.70

cerebellum:92.10

brain stem:95.30

corpus callosum/glia:-

pineal gland:-

peripheral nerve:38.20

spine:141.90

retina:128.60

eye:83.60

artery/aorta:84.40

vein:-

lymphnode:32.40

peripheral blood:201.30

spleen:26.30

thymus:168

bone marrow:51.30

adipose:850.90

bone:37.60

skin:47.50

GeneChip

cerebrum:9.57

cerebellum:9.85

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:9.02

spine:9.90

retina:10.30

eye:10

artery/aorta:-

vein:9.03

lymphnode:8.62

peripheral blood:-

spleen:8.66

thymus:-

bone marrow:8.08

adipose:9.67

bone:8.56

skin:9.44

CAGE

cerebrum:3.35

cerebellum:-

brain stem:3.50

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:3.67

retina:-

eye:-

artery/aorta:3.92

vein:-

lymphnode:1.47

peripheral blood:-

spleen:2.67

thymus:3.18

bone marrow:-

adipose:-

bone:3.35

skin:3.53

RNA-seq

cerebrum:12.11

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:-

placenta:27.60

prostate:61.80

ovary:114.90

testis:14.80

heart:186

muscle:71

esophagus:-

stomach:98.20

intestine:37

colon:17.60

liver/hepato:27.20

lung:100.40

bladder:66.20

kidney:96.70

pituitary:77.50

thyroid/parathyroid:112.50

adrenal gland:-

pancreas:28.10

breast:78.40

salivary:-

GeneChip

uterus:10.21

placenta:8.70

prostate:9.66

ovary:9.30

testis:6.89

heart:12.08

muscle:11.52

esophagus:-

stomach:9.22

intestine:9.03

colon:-

liver/hepato:8.51

lung:9.67

bladder:9.66

kidney:9.59

pituitary:8.55

thyroid/parathyroid:-

adrenal gland:9.57

pancreas:8.86

breast:9.56

salivary:9.51

CAGE

uterus:4.17

placenta:3.29

prostate:3.20

ovary:3.22

testis:2.05

heart:-

muscle:-

esophagus:-

stomach:3.67

intestine:3.16

colon:3.05

liver/hepato:3.02

lung:3.32

bladder:3.58

kidney:-

pituitary:3.06

thyroid/parathyroid:-

adrenal gland:3.09

pancreas:3.10

breast:2.89

salivary:-

RNA-seq

uterus:-

placenta:-

prostate:-

ovary:-

testis:-

heart:-

muscle:43.38

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:3.94

lung:-

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

IDs

Refseq ID	NM_053207
Gene ID	112405
Unigene ID	Mm.140619
Probe set ID	1423785_at [Mouse430_2]
Ensembl ID	ENSMUSG00000031987

Orthologous Gene

Human[2]	NM_022051
Rat[2]	NM_022051

Chromosomal Region

Gene Family (Interpro ID)

IPR005123	Oxoglutarate/iron-dependent oxygenase
IPR006620	Prolyl 4-hydroxylase, alpha subunit

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

GO:0055008	cardiac muscle tissue morphogenesis
GO:0060347	heart trabecula formation
GO:0060711	labyrinthine layer development
GO:0043433	negative regulation of transcription factor activity
GO:0055114	oxidation reduction
GO:0032364	oxygen homeostasis
GO:0018401	peptidyl-proline hydroxylation to 4-hydroxy-L-proline
GO:0045765	regulation of angiogenesis
GO:0001666	response to hypoxia
GO:0060412	ventricular septum morphogenesis

Cellular Component

GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005634	nucleus

Molecular Function

GO:0005506	iron ion binding
GO:0031418	L-ascorbic acid binding
GO:0046872	metal ion binding
GO:0016491	oxidoreductase activity
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0016706	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
GO:0031545	peptidyl-proline 4-dioxygenase activity
GO:0031543	peptidyl-proline dioxygenase activity

EGL nine homolog 1 (C. elegans)

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function