adrenergic receptor, beta 1

Synonym

beta-AR, Beta-1 adrenoceptor, Beta-1 adrenergic receptor, beta 1-AR, Beta-1 adrenoreceptor, adrenergic receptor, beta 1, Adrb1, Adrb-1, Adrb1r

normal 40 tissues
developmental tissues and primary cells（FANTOM5 CAGE）

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:20.80

cerebellum:-

brain stem:31.80

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:189.10

retina:64.30

eye:7.60

artery/aorta:253.20

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:19.80

bone marrow:-

adipose:-

bone:-

skin:-

GeneChip

cerebrum:6.54

cerebellum:4.60

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:4.23

spine:4.93

retina:5.99

eye:5.15

artery/aorta:-

vein:4.64

lymphnode:4.45

peripheral blood:-

spleen:5.16

thymus:-

bone marrow:4.25

adipose:5.60

bone:4.19

skin:4.19

CAGE

cerebrum:2.03

cerebellum:-

brain stem:2.37

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:1.73

retina:-

eye:-

artery/aorta:3.44

vein:-

lymphnode:0.23

peripheral blood:-

spleen:1.76

thymus:0.95

bone marrow:-

adipose:-

bone:0

skin:1.20

RNA-seq

cerebrum:3.59

cerebellum:3.59

brain stem:3.59

corpus callosum/glia:3.59

pineal gland:3.59

peripheral nerve:3.59

spine:3.59

retina:3.59

eye:3.59

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:-

placenta:13.80

prostate:-

ovary:-

testis:7.40

heart:-

muscle:-

esophagus:-

stomach:-

intestine:-

colon:17.60

liver/hepato:-

lung:10

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:13.10

salivary:-

GeneChip

uterus:4.37

placenta:6.36

prostate:4.29

ovary:4.24

testis:4.47

heart:6.91

muscle:4.31

esophagus:-

stomach:4.31

intestine:4.33

colon:-

liver/hepato:4.31

lung:8.75

bladder:4.27

kidney:4.66

pituitary:4.34

thyroid/parathyroid:-

adrenal gland:4.60

pancreas:5.31

breast:4.80

salivary:10.31

CAGE

uterus:0.90

placenta:2.38

prostate:0.20

ovary:0.82

testis:0.45

heart:-

muscle:-

esophagus:-

stomach:0

intestine:0.58

colon:1.03

liver/hepato:0.78

lung:4.19

bladder:0.18

kidney:-

pituitary:0.86

thyroid/parathyroid:-

adrenal gland:1.30

pancreas:2.19

breast:2.56

salivary:-

RNA-seq

uterus:-

placenta:-

prostate:-

ovary:-

testis:-

heart:-

muscle:-

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:-

lung:-

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

IDs

Refseq ID	NM_007419
Gene ID	11554
Unigene ID	Mm.46797
Probe set ID	1423420_at [Mouse430_2]
Ensembl ID	ENSMUSG00000035283

Orthologous Gene

Human[1]	NM_000684
Rat[1]	NM_012701

Chromosomal Region

Gene Family (Interpro ID)

IPR000276	7TM GPCR, rhodopsin-like
IPR002233	Adrenergic receptor
IPR000507	Adrenergic receptor, beta 1
IPR017452	GPCR, rhodopsin-like superfamily

Gene Ontology (GO ID)

Biological Process

GO:0007189	activation of adenylate cyclase activity by G-protein signaling pathway
GO:0006915	apoptosis
GO:0050873	brown fat cell differentiation
GO:0002024	diet induced thermogenesis
GO:0042596	fear response
GO:0007186	G-protein coupled receptor protein signaling pathway
GO:0005980	glycogen catabolic process
GO:0031649	heat generation
GO:0055088	lipid homeostasis
GO:0007613	memory
GO:0040015	negative regulation of multicellular organism growth
GO:0045986	negative regulation of smooth muscle contraction
GO:0045762	positive regulation of adenylate cyclase activity
GO:0043065	positive regulation of apoptosis
GO:0030819	positive regulation of cAMP biosynthetic process
GO:0045823	positive regulation of heart contraction
GO:0010460	positive regulation of heart rate
GO:0001996	positive regulation of heart rate by epinephrine-norepinephrine
GO:0046878	positive regulation of saliva secretion
GO:0003084	positive regulation of systemic arterial blood pressure
GO:0001997	positive regulation of the force of heart contraction by epinephrine-norepinephrine
GO:0003061	positive regulation of the force of heart contraction by norepinephrine
GO:0033365	protein localization in organelle
GO:0051924	regulation of calcium ion transport
GO:0060080	regulation of inhibitory postsynaptic membrane potential
GO:0009409	response to cold
GO:0007266	Rho protein signal transduction
GO:0019233	sensory perception of pain
GO:0007165	signal transduction
GO:0002025	vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure
GO:0042060	wound healing

Cellular Component

GO:0005737	cytoplasm
GO:0016021	integral to membrane
GO:0043231	intracellular membrane-bounded organelle
GO:0016020	membrane
GO:0005634	nucleus
GO:0005886	plasma membrane

Molecular Function

GO:0004935	adrenoceptor activity
GO:0031694	alpha-2A adrenergic receptor binding
GO:0004940	beta1-adrenergic receptor activity
GO:0035240	dopamine binding
GO:0008144	drug binding
GO:0051379	epinephrine binding
GO:0004930	G-protein coupled receptor activity
GO:0051380	norepinephrine binding
GO:0030165	PDZ domain binding
GO:0046982	protein heterodimerization activity
GO:0004871	signal transducer activity

adrenergic receptor, beta 1

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function