advanced glycosylation end product-specific receptor

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Synonym

Rage, RAGE, Ager, Receptor for advanced glycosylation end products

normal 40 tissues
developmental tissues and primary cells（FANTOM5 CAGE）

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:19.10

cerebellum:18.40

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:38.20

spine:94.60

retina:96.40

eye:15.20

artery/aorta:-

vein:-

lymphnode:54

peripheral blood:-

spleen:-

thymus:59.30

bone marrow:-

adipose:-

bone:25

skin:15.80

GeneChip

cerebrum:6.08

cerebellum:6.03

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:6.09

spine:5.99

retina:6.02

eye:6.25

artery/aorta:-

vein:6.30

lymphnode:6.07

peripheral blood:-

spleen:6.28

thymus:-

bone marrow:6.33

adipose:6.08

bone:6.02

skin:6.12

CAGE

cerebrum:0

cerebellum:-

brain stem:0

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:0

retina:-

eye:-

artery/aorta:0

vein:-

lymphnode:0.42

peripheral blood:-

spleen:0.29

thymus:0

bone marrow:-

adipose:-

bone:0

skin:0

RNA-seq

cerebrum:1.10

cerebellum:1.10

brain stem:1.10

corpus callosum/glia:1.10

pineal gland:1.10

peripheral nerve:1.10

spine:1.10

retina:1.10

eye:1.10

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:87.20

placenta:-

prostate:-

ovary:149.40

testis:103.50

heart:-

muscle:-

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:-

lung:20.10

bladder:66.20

kidney:16.10

pituitary:64.60

thyroid/parathyroid:112.50

adrenal gland:-

pancreas:-

breast:3.30

salivary:-

GeneChip

uterus:5.93

placenta:6.53

prostate:5.90

ovary:5.61

testis:6.11

heart:6.23

muscle:6.19

esophagus:-

stomach:6.12

intestine:5.75

colon:-

liver/hepato:6.13

lung:13.52

bladder:6

kidney:6.35

pituitary:6.28

thyroid/parathyroid:-

adrenal gland:5.65

pancreas:6.70

breast:5.82

salivary:6.34

CAGE

uterus:0.44

placenta:0.77

prostate:0.37

ovary:0

testis:0

heart:-

muscle:-

esophagus:-

stomach:0

intestine:0

colon:0

liver/hepato:0

lung:6.93

bladder:0.46

kidney:-

pituitary:0

thyroid/parathyroid:-

adrenal gland:0

pancreas:1.30

breast:0.20

salivary:-

RNA-seq

uterus:-

placenta:-

prostate:-

ovary:-

testis:-

heart:-

muscle:-

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:-

lung:-

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

IDs

Refseq ID	NM_007425
Gene ID	11596
Unigene ID	Mm.33830
Probe set ID	1420428_at [Mouse430_2]
Ensembl ID	ENSMUSG00000015452

Orthologous Gene

Human[1]	NM_001136, NM_001206929, NM_001206932, NM_001206966, NM_172197
Rat [0]

Chromosomal Region

Gene Family (Interpro ID)

Gene Ontology (GO ID)

Biological Process

GO:0055074	calcium ion homeostasis
GO:0050930	induction of positive chemotaxis
GO:0006954	inflammatory response
GO:0007259	JAK-STAT cascade
GO:0007162	negative regulation of cell adhesion
GO:0032966	negative regulation of collagen biosynthetic process
GO:0010596	negative regulation of endothelial cell migration
GO:0001937	negative regulation of endothelial cell proliferation
GO:0001933	negative regulation of protein amino acid phosphorylation
GO:0031175	neuron projection development
GO:0043065	positive regulation of apoptosis
GO:0010508	positive regulation of autophagy
GO:0030335	positive regulation of cell migration
GO:0010718	positive regulation of epithelial to mesenchymal transition
GO:0010763	positive regulation of fibroblast migration
GO:0048146	positive regulation of fibroblast proliferation
GO:0010628	positive regulation of gene expression
GO:0050729	positive regulation of inflammatory response
GO:0043525	positive regulation of neuron apoptosis
GO:0051092	positive regulation of NF-kappaB transcription factor activity
GO:0001934	positive regulation of protein amino acid phosphorylation
GO:0014911	positive regulation of smooth muscle cell migration
GO:0048661	positive regulation of smooth muscle cell proliferation
GO:0050727	regulation of inflammatory response

Cellular Component

GO:0030424	axon
GO:0009925	basal plasma membrane
GO:0043025	cell soma
GO:0009986	cell surface
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005615	extracellular space
GO:0016021	integral to membrane
GO:0016020	membrane
GO:0005886	plasma membrane

Molecular Function

GO:0050785	advanced glycation end-product receptor activity
GO:0070379	high mobility group box 1 binding
GO:0005515	protein binding

advanced glycosylation end product-specific receptor

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function