adaptor protein complex AP-1, sigma 1

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Synonym

Clathrin coat assembly protein AP19, AP-1 complex subunit sigma-1A, Adapter-related protein complex 1 sigma-1A subunit, Golgi adaptor HA1/AP1 adaptin sigma-1A subunit, AP19, adaptor protein complex AP-1, sigma 1, Ap19, Ap1s1, Sigma-adaptin 1A, Adaptor protein complex AP-1 sigma-1A subunit, HA1 19 kDa subunit, Sigma 1a subunit of AP-1 clathrin

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:291.70 cerebellum:55.30 brain stem:63.60 corpus callosum/glia:- pineal gland:257.80 peripheral nerve:38.20 spine:236.40 retina:- eye:30.40 artery/aorta:84.40 vein:- lymphnode:43.20 peripheral blood:100.60 spleen:13.20 thymus:69.20 bone marrow:141 adipose:212.70 bone:187.90 skin:47.50
GeneChip cerebrum:10.61 cerebellum:8.96 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:9.70 spine:9.48 retina:7.68 eye:7.60 artery/aorta:- vein:8.94 lymphnode:8.26 peripheral blood:- spleen:8.02 thymus:- bone marrow:8.46 adipose:8.76 bone:8.08 skin:8
CAGE cerebrum:3.72 cerebellum:- brain stem:3.87 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:3.61 retina:- eye:- artery/aorta:3.06 vein:- lymphnode:2.33 peripheral blood:- spleen:2.64 thymus:2.54 bone marrow:- adipose:- bone:2.83 skin:3.33
RNA-seq cerebrum:72.07 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:130.90 placenta:151.90 prostate:30.90 ovary:11.50 testis:14.80 heart:148.80 muscle:142 esophagus:- stomach:32.70 intestine:110.90 colon:475.80     liver/hepato:81.50        lung:210.90    bladder:- kidney:104.80 pituitary:116.30 thyroid/parathyroid:112.50 adrenal gland:- pancreas:9.40 breast:137.10 salivary:-
GeneChip uterus:9.22 placenta:9.27 prostate:8.67 ovary:8.65 testis:7.94 heart:8.16 muscle:8.04 esophagus:- stomach:9.48 intestine:9.68 colon:- liver/hepato:8.47 lung:8.36 bladder:8.70 kidney:9.11 pituitary:8.79 thyroid/parathyroid:- adrenal gland:8.91 pancreas:8.13 breast:8.60 salivary:8.86
CAGE uterus:3.49 placenta:3.61 prostate:2.83 ovary:2.98 testis:2.68 heart:- muscle:- esophagus:- stomach:4.13 intestine:3.70 colon:3.68     liver/hepato:3.02    lung:2.90 bladder:3.28 kidney:- pituitary:2.98 thyroid/parathyroid:- adrenal gland:3.00 pancreas:2.56 breast:3.16 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:6.73 esophagus:- stomach:- intestine:- colon:-     liver/hepato:6.54        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_007457
Gene ID 11769
Unigene ID Mm.833
Probe set ID 1416087_at  [Mouse430_2]
Ensembl ID ENSMUSG00000004849

Orthologous Gene

Human[3]  NM_001283
Rat[2]  NM_001108331

Chromosomal Region

-

Gene Family (Interpro ID)

IPR016635  Adaptor protein complex, sigma subunit
IPR000804  Clathrin adaptor, sigma subunit/coatomer, zeta subunit

Link to Pubmed  (Pubmed ID)

2040623
8631897
8723999
9714600
9733768
10349636
10725249
10922068
11042159
11076861
11217851
12466851
12477932
14610273
15489334
15688012
15782199
15791649
16141072
16141073
16213465
17114649
17360967
18799693
21677750

Gene Ontology  (GO ID)

Biological Process

GO:0006897  endocytosis
GO:0006886  intracellular protein transport
GO:0015031  protein transport
GO:0006810  transport
GO:0016192  vesicle-mediated transport

Cellular Component

GO:0030121  AP-1 adaptor complex
GO:0005905  coated pit
GO:0031410  cytoplasmic vesicle
GO:0005794  Golgi apparatus
GO:0016020  membrane
GO:0030117  membrane coat
GO:0005802  trans-Golgi network

Molecular Function

GO:0005515  protein binding
GO:0008565  protein transporter activity