cyclin-dependent kinase 5, regulatory subunit 1 (p35)

Synonym

Cdk5r1, Cdk5r, Tau protein kinase II 23 kDa subunit, Cyclin-dependent kinase 5 activator 1 precursor, Cyclin-dependent kinase 5 regulatory subunit 1, CDK5 activator 1, D11Bwg0379e, TPKII regulatory subunit, Nck5a

normal 40 tissues
developmental tissues and primary cells（FANTOM5 CAGE）

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:234.40

cerebellum:902.60

brain stem:349.60

corpus callosum/glia:-

pineal gland:-

peripheral nerve:152.90

spine:520.10

retina:160.70

eye:53.20

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:29.60

bone marrow:-

adipose:-

bone:12.50

skin:23.80

GeneChip

cerebrum:7.02

cerebellum:5.82

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:5.62

spine:5.79

retina:4.93

eye:5.11

artery/aorta:-

vein:4.89

lymphnode:4.91

peripheral blood:-

spleen:4.90

thymus:-

bone marrow:5.44

adipose:4.95

bone:5.31

skin:4.84

CAGE

cerebrum:4.11

cerebellum:-

brain stem:4.02

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:3.60

retina:-

eye:-

artery/aorta:0.46

vein:-

lymphnode:1.03

peripheral blood:-

spleen:0.79

thymus:1.50

bone marrow:-

adipose:-

bone:1.69

skin:1.25

RNA-seq

cerebrum:17.30

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:-

placenta:-

prostate:-

ovary:-

testis:7.40

heart:-

muscle:-

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:-

lung:10

bladder:-

kidney:-

pituitary:12.90

thyroid/parathyroid:-

adrenal gland:424.40

pancreas:9.40

breast:-

salivary:-

GeneChip

uterus:4.78

placenta:5.31

prostate:4.79

ovary:4.60

testis:4.86

heart:5.10

muscle:5.26

esophagus:-

stomach:4.93

intestine:4.80

colon:-

liver/hepato:5.32

lung:4.53

bladder:5.08

kidney:4.99

pituitary:4.92

thyroid/parathyroid:-

adrenal gland:4.83

pancreas:5.94

breast:4.84

salivary:5.10

CAGE

uterus:0.55

placenta:1.43

prostate:0

ovary:0.82

testis:0.45

heart:-

muscle:-

esophagus:-

stomach:0

intestine:0.23

colon:0.41

liver/hepato:0.47

lung:0.31

bladder:0.33

kidney:-

pituitary:2.39

thyroid/parathyroid:-

adrenal gland:1.30

pancreas:0

breast:0.22

salivary:-

RNA-seq

uterus:-

placenta:-

prostate:-

ovary:-

testis:-

heart:-

muscle:0.47

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:0

lung:-

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

IDs

Refseq ID	NM_009871
Gene ID	12569
Unigene ID	Mm.142275
Probe set ID	1421124_at [Mouse430_2]
Ensembl ID	ENSMUSG00000048895

Orthologous Gene

Human[2]	NM_003885
Rat [0]

Chromosomal Region

Gene Family (Interpro ID)

Gene Ontology (GO ID)

Biological Process

GO:0007411	axon guidance
GO:0007413	axonal fasciculation
GO:0007420	brain development
GO:0021549	cerebellum development
GO:0021799	cerebral cortex radially oriented cell migration
GO:0009790	embryonic development
GO:0048013	ephrin receptor signaling pathway
GO:0021766	hippocampus development
GO:0035235	ionotropic glutamate receptor signaling pathway
GO:0021819	layer formation in the cerebral cortex
GO:0007213	muscarinic acetylcholine receptor signaling pathway
GO:0030517	negative regulation of axon extension
GO:0045892	negative regulation of transcription, DNA-dependent
GO:0007158	neuron adhesion
GO:0030182	neuron differentiation
GO:0001764	neuron migration
GO:0031175	neuron projection development
GO:0018105	peptidyl-serine phosphorylation
GO:0018107	peptidyl-threonine phosphorylation
GO:0016310	phosphorylation
GO:0043525	positive regulation of neuron apoptosis
GO:0045860	positive regulation of protein kinase activity
GO:0006468	protein amino acid phosphorylation
GO:0032956	regulation of actin cytoskeleton organization
GO:0070507	regulation of microtubule cytoskeleton organization
GO:0033136	serine phosphorylation of STAT3 protein
GO:0021722	superior olivary nucleus maturation

Cellular Component

GO:0030424	axon
GO:0043025	cell soma
GO:0043292	contractile fiber
GO:0016533	cyclin-dependent protein kinase 5 holoenzyme complex
GO:0005737	cytoplasm
GO:0030425	dendrite
GO:0043197	dendritic spine
GO:0030426	growth cone
GO:0016020	membrane
GO:0031594	neuromuscular junction
GO:0005634	nucleus
GO:0048471	perinuclear region of cytoplasm
GO:0005886	plasma membrane
GO:0014069	postsynaptic density

Molecular Function

GO:0045296	cadherin binding
GO:0005509	calcium ion binding
GO:0016534	cyclin-dependent protein kinase 5 activator activity
GO:0004693	cyclin-dependent protein kinase activity
GO:0008092	cytoskeletal protein binding
GO:0046875	ephrin receptor binding
GO:0016301	kinase activity
GO:0005515	protein binding
GO:0019901	protein kinase binding
GO:0043539	protein serine/threonine kinase activator activity
GO:0016740	transferase activity

cyclin-dependent kinase 5, regulatory subunit 1 (p35)

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function