complement component factor i

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Synonym

Cfi, complement component factor i, If, C3B/C4B inactivator, Complement factor I precursor

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:3.50 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:21.60 peripheral blood:28.80 spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip cerebrum:4.98 cerebellum:4.73 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:4.85 spine:4.85 retina:6.30 eye:5.69 artery/aorta:- vein:4.90 lymphnode:5.06 peripheral blood:- spleen:4.71 thymus:- bone marrow:4.77 adipose:6.24 bone:4.85 skin:4.91
CAGE cerebrum:0 cerebellum:- brain stem:0 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:0 retina:- eye:- artery/aorta:0.14 vein:- lymphnode:0.23 peripheral blood:- spleen:0 thymus:0 bone marrow:- adipose:- bone:0 skin:0
RNA-seq cerebrum:4.29 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:193.30 prostate:- ovary:- testis:- heart:- muscle:177.50 esophagus:- stomach:65.50 intestine:- colon:-     liver/hepato:262.50        lung:10    bladder:- kidney:8.10 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:28.10 breast:9.80 salivary:-
GeneChip uterus:10.80 placenta:9.65 prostate:5 ovary:8.40 testis:4.94 heart:5.20 muscle:4.86 esophagus:- stomach:10.25 intestine:5.98 colon:- liver/hepato:13.27 lung:7.55 bladder:5.08 kidney:7.05 pituitary:5.91 thyroid/parathyroid:- adrenal gland:5.97 pancreas:5.26 breast:4.99 salivary:5.33
CAGE uterus:3.98 placenta:2.88 prostate:0.37 ovary:1.58 testis:0 heart:- muscle:- esophagus:- stomach:4.44 intestine:1.75 colon:1.89     liver/hepato:6.99    lung:0.17 bladder:0.57 kidney:- pituitary:0 thyroid/parathyroid:- adrenal gland:1.77 pancreas:0 breast:0 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:148.41        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_007686
Gene ID 12630
Unigene ID Mm.117180
Probe set ID 1418724_at  [Mouse430_2]
Ensembl ID ENSMUSG00000058952

Orthologous Gene

Human[1]  NM_000204
Rat[1]  NM_000204

Chromosomal Region

-

Gene Family (Interpro ID)

IPR001254  Peptidase S1/S6, chymotrypsin/Hap
IPR001314  Peptidase S1A, chymotrypsin
IPR009003  Serine/cysteine peptidase, trypsin-like
IPR001190  Speract/scavenger receptor
IPR017448  Speract/scavenger receptor related

Link to Pubmed  (Pubmed ID)

8604219
10204086
10583609
10922068
12466851
12477932
12618913
12819125
14691545
16141072
16944957
17330941
18167345
18202746
19423168
21267068
23341629
24474777

Gene Ontology  (GO ID)

Biological Process

GO:0006958  complement activation, classical pathway
GO:0045087  innate immune response
GO:0006508  proteolysis

Cellular Component

GO:0005576  extracellular region
GO:0016020  membrane

Molecular Function

GO:0003824  catalytic activity
GO:0016787  hydrolase activity
GO:0046872  metal ion binding
GO:0008233  peptidase activity
GO:0005044  scavenger receptor activity
GO:0004252  serine-type endopeptidase activity
GO:0008236  serine-type peptidase activity