chemokine (C-C motif) receptor 1

Synonym

CC-CKR-1, C-C chemokine receptor type 1, CCR-1, C-C CKR-1, MIP-1 alphaR, CCR1, Cmkbr1, MIP-1alpha-R, RANTES-R, CD191 antigen, Macrophage inflammatory protein 1-alpha receptor, Mip-1a-R, chemokine (C-C motif) receptor 1, Ccr1

normal 40 tissues
developmental tissues and primary cells（FANTOM5 CAGE）

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:3.50

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:47.30

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:43.20

peripheral blood:57.50

spleen:13.20

thymus:-

bone marrow:12.80

adipose:-

bone:62.60

skin:23.80

GeneChip

cerebrum:4.01

cerebellum:3.99

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:4.05

spine:4.17

retina:3.98

eye:4.42

artery/aorta:-

vein:5.42

lymphnode:6.65

peripheral blood:-

spleen:6.47

thymus:-

bone marrow:9.54

adipose:5.33

bone:9.44

skin:4.38

CAGE

cerebrum:0

cerebellum:-

brain stem:0.31

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:0.75

retina:-

eye:-

artery/aorta:2.24

vein:-

lymphnode:2.82

peripheral blood:-

spleen:2.88

thymus:1.06

bone marrow:-

adipose:-

bone:3.79

skin:1.42

RNA-seq

cerebrum:-

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:-

placenta:-

prostate:-

ovary:-

testis:-

heart:18.60

muscle:-

esophagus:-

stomach:-

intestine:-

colon:17.60

liver/hepato:54.30

lung:20.10

bladder:66.20

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:46.90

breast:19.60

salivary:-

GeneChip

uterus:4.66

placenta:5.07

prostate:4.70

ovary:4.38

testis:4.32

heart:4.75

muscle:4.26

esophagus:-

stomach:5.16

intestine:5.46

colon:-

liver/hepato:3.94

lung:6.41

bladder:5.01

kidney:4.13

pituitary:3.90

thyroid/parathyroid:-

adrenal gland:4.99

pancreas:4.54

breast:5.49

salivary:4.78

CAGE

uterus:1.22

placenta:0.80

prostate:0.74

ovary:0.94

testis:0.45

heart:-

muscle:-

esophagus:-

stomach:2.16

intestine:1.84

colon:2.10

liver/hepato:0.47

lung:3.02

bladder:2.02

kidney:-

pituitary:0.29

thyroid/parathyroid:-

adrenal gland:2.02

pancreas:0.84

breast:1.59

salivary:-

RNA-seq

uterus:-

placenta:-

prostate:-

ovary:-

testis:-

heart:-

muscle:1.45

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:0

lung:-

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

IDs

Refseq ID	NM_009912
Gene ID	12768
Unigene ID	Mm.274927
Probe set ID	1419609_at [Mouse430_2]
Ensembl ID	ENSMUSG00000025804

Orthologous Gene

Human[2]	NM_001295
Rat [0]

Chromosomal Region

Gene Family (Interpro ID)

IPR000276	7TM GPCR, rhodopsin-like
IPR000248	Angiotensin II receptor
IPR002236	C-C chemokine receptor, type 1
IPR002238	C-C chemokine receptor, type 3
IPR002240	C-C chemokine receptor, type 5
IPR000355	Chemokine receptor
IPR017452	GPCR, rhodopsin-like superfamily
IPR002286	P2 purinoceptor

Gene Ontology (GO ID)

Biological Process

GO:0006816	calcium ion transport
GO:0007267	cell-cell signaling
GO:0006874	cellular calcium ion homeostasis
GO:0070098	chemokine-mediated signaling pathway
GO:0006935	chemotaxis
GO:0007204	elevation of cytosolic calcium ion concentration
GO:0006887	exocytosis
GO:0007186	G-protein coupled receptor protein signaling pathway
GO:0006955	immune response
GO:0006954	inflammatory response
GO:0030595	leukocyte chemotaxis
GO:0030099	myeloid cell differentiation
GO:0030502	negative regulation of bone mineralization
GO:0010629	negative regulation of gene expression
GO:0045824	negative regulation of innate immune response
GO:0051928	positive regulation of calcium ion transport
GO:0070374	positive regulation of ERK1 and ERK2 cascade
GO:0090026	positive regulation of monocyte chemotaxis
GO:0045672	positive regulation of osteoclast differentiation
GO:0031620	regulation of fever
GO:0032496	response to lipopolysaccharide
GO:0007165	signal transduction

Cellular Component

GO:0043025	cell soma
GO:0009897	external side of plasma membrane
GO:0016021	integral to membrane
GO:0016020	membrane
GO:0005886	plasma membrane

Molecular Function

GO:0019957	C-C chemokine binding
GO:0016493	C-C chemokine receptor activity
GO:0004950	chemokine receptor activity
GO:0004930	G-protein coupled receptor activity
GO:0004435	phosphoinositide phospholipase C activity
GO:0005515	protein binding
GO:0004871	signal transducer activity

chemokine (C-C motif) receptor 1

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function