corticotropin releasing hormone receptor 1

Synonym

CRF1, CRF 1 receptor, Corticotropin-releasing hormone receptor 1, MGC124240, CRFR1, MGC124237, CRF-R, CRF-R1alpha, Crhr1, corticotropin releasing hormone receptor 1, CRH-R 1, Crhr

normal 40 tissues
developmental tissues and primary cells（FANTOM5 CAGE）

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:-

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:7.90

GeneChip

cerebrum:6.12

cerebellum:7.97

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:5.47

spine:6.25

retina:5.30

eye:5.60

artery/aorta:-

vein:5.67

lymphnode:5.55

peripheral blood:-

spleen:5.53

thymus:-

bone marrow:5.33

adipose:5.64

bone:5.49

skin:5.56

CAGE

cerebrum:2.30

cerebellum:-

brain stem:1.49

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:0.91

retina:-

eye:-

artery/aorta:0

vein:-

lymphnode:0

peripheral blood:-

spleen:0.62

thymus:0

bone marrow:-

adipose:-

bone:0

skin:0.15

RNA-seq

cerebrum:5.85

cerebellum:5.85

brain stem:5.85

corpus callosum/glia:5.85

pineal gland:5.85

peripheral nerve:5.85

spine:5.85

retina:5.85

eye:5.85

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:-

placenta:-

prostate:-

ovary:-

testis:-

heart:18.60

muscle:-

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:-

lung:-

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:9.40

breast:-

salivary:-

GeneChip

uterus:5.61

placenta:5.39

prostate:5.57

ovary:5.59

testis:5.51

heart:5.92

muscle:5.59

esophagus:-

stomach:5.64

intestine:5.65

colon:-

liver/hepato:5.80

lung:5.89

bladder:6.15

kidney:5.68

pituitary:5.85

thyroid/parathyroid:-

adrenal gland:5.39

pancreas:5.84

breast:5.87

salivary:5.76

CAGE

uterus:0

placenta:0

prostate:0.37

ovary:0.13

testis:0

heart:-

muscle:-

esophagus:-

stomach:0

intestine:0

colon:0

liver/hepato:0

lung:0

bladder:0

kidney:-

pituitary:2.01

thyroid/parathyroid:-

adrenal gland:0

pancreas:0

breast:0

salivary:-

RNA-seq

uterus:-

placenta:-

prostate:-

ovary:-

testis:-

heart:-

muscle:-

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:-

lung:-

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

IDs

Refseq ID	NM_007762
Gene ID	12921
Unigene ID	Mm.189201
Probe set ID	1427782_a_at [Mouse430_2]
Ensembl ID	ENSMUSG00000018634

Orthologous Gene

Human[12]	NM_001145146, NM_001145147, NM_001145148, NM_004382
Rat [0]

Chromosomal Region

Gene Family (Interpro ID)

IPR003051	GPCR, family 2, corticotropin releasing factor receptor
IPR003052	GPCR, family 2, corticotropin releasing factor receptor, type 1
IPR002001	GPCR, family 2, diuretic hormone receptor
IPR000832	GPCR, family 2, secretin-like
IPR017981	GPCR, family 2-like

Gene Ontology (GO ID)

Biological Process

GO:0007189	activation of adenylate cyclase activity by G-protein signaling pathway
GO:0007200	activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger
GO:0048148	behavioral response to cocaine
GO:0048149	behavioral response to ethanol
GO:0048266	behavioral response to pain
GO:0007166	cell surface receptor linked signal transduction
GO:0071376	cellular response to corticotropin-releasing hormone stimulus
GO:0042755	eating behavior
GO:0007204	elevation of cytosolic calcium ion concentration
GO:0030855	epithelial cell differentiation
GO:0007186	G-protein coupled receptor protein signaling pathway
GO:0007188	G-protein signaling, coupled to cAMP nucleotide second messenger
GO:0051867	general adaptation syndrome, behavioral process
GO:0009755	hormone-mediated signaling pathway
GO:0060291	long-term synaptic potentiation
GO:0007613	memory
GO:0032099	negative regulation of appetite
GO:0032811	negative regulation of epinephrine secretion
GO:0007218	neuropeptide signaling pathway
GO:0030819	positive regulation of cAMP biosynthetic process
GO:0043306	positive regulation of mast cell degranulation
GO:0048167	regulation of synaptic plasticity
GO:0001666	response to hypoxia
GO:0006950	response to stress
GO:0007165	signal transduction
GO:0008542	visual learning

Cellular Component

GO:0045177	apical part of cell
GO:0033267	axon part
GO:0043025	cell soma
GO:0030425	dendrite
GO:0016021	integral to membrane
GO:0016020	membrane
GO:0005771	multivesicular body
GO:0005886	plasma membrane
GO:0005802	trans-Golgi network
GO:0031982	vesicle

Molecular Function

GO:0015056	corticotrophin-releasing factor receptor activity
GO:0051424	corticotropin-releasing hormone binding
GO:0043404	corticotropin-releasing hormone receptor activity
GO:0001965	G-protein alpha-subunit binding
GO:0004930	G-protein coupled receptor activity
GO:0042277	peptide binding
GO:0032403	protein complex binding
GO:0004871	signal transducer activity
GO:0004888	transmembrane receptor activity

corticotropin releasing hormone receptor 1

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function