sphingosine-1-phosphate receptor 1

Synonym

Edg1, S1P1, lpB1, Lpb1, AI849002, Sphingosine 1-phosphate receptor 1, Lysophospholipid receptor B1, Sphingosine 1-phosphate receptor Edg-1, IpB1

normal 40 tissues
developmental tissues and primary cells（FANTOM5 CAGE）

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

nodata

GeneChip

cerebrum:9.21

cerebellum:9.41

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:6.83

spine:9.33

retina:6.20

eye:6.10

artery/aorta:-

vein:7.12

lymphnode:10.12

peripheral blood:-

spleen:9.57

thymus:-

bone marrow:7.20

adipose:8.23

bone:7.46

skin:6.49

CAGE

cerebrum:4.96

cerebellum:-

brain stem:5.00

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:4.97

retina:-

eye:-

artery/aorta:4.66

vein:-

lymphnode:5.63

peripheral blood:-

spleen:4.49

thymus:3.19

bone marrow:-

adipose:-

bone:3.54

skin:2.93

RNA-seq

cerebrum:17.95

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

nodata

GeneChip

uterus:6.98

placenta:7.22

prostate:6.63

ovary:7.08

testis:5.79

heart:8.65

muscle:8.20

esophagus:-

stomach:6.44

intestine:5.95

colon:-

liver/hepato:8.56

lung:10.89

bladder:7.13

kidney:6.79

pituitary:6.17

thyroid/parathyroid:-

adrenal gland:7.31

pancreas:6.79

breast:7.97

salivary:5.91

CAGE

uterus:3.20

placenta:3.75

prostate:1.87

ovary:3.11

testis:0

heart:-

muscle:-

esophagus:-

stomach:2.44

intestine:2.13

colon:2.19

liver/hepato:5.01

lung:5.77

bladder:3.11

kidney:-

pituitary:2.71

thyroid/parathyroid:-

adrenal gland:3.28

pancreas:2.75

breast:3.62

salivary:-

RNA-seq

uterus:-

placenta:-

prostate:-

ovary:-

testis:-

heart:-

muscle:2.16

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:3.44

lung:-

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

IDs

Refseq ID	NM_007901
Gene ID	13609
Unigene ID	-
Probe set ID	1423571_at [Mouse430_2]
Ensembl ID	ENSMUSG00000045092

Orthologous Gene

Human[1]	NM_001400
Rat[1]	NM_017301

Chromosomal Region

Gene Family (Interpro ID)

IPR000276	7TM GPCR, rhodopsin-like
IPR000987	EDG-1 sphingosine 1-phosphate receptor
IPR017452	GPCR, rhodopsin-like superfamily
IPR001671	Melanocortin/ACTH receptor
IPR004061	Sphingosine 1-phosphate receptor

Gene Ontology (GO ID)

Biological Process

GO:0001525	angiogenesis
GO:0007420	brain development
GO:0051482	elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)
GO:0007186	G-protein coupled receptor protein signaling pathway
GO:0007193	inhibition of adenylate cyclase activity by G-protein signaling pathway
GO:0051497	negative regulation of stress fiber formation
GO:0030335	positive regulation of cell migration
GO:0008284	positive regulation of cell proliferation
GO:0050927	positive regulation of positive chemotaxis
GO:0032320	positive regulation of Ras GTPase activity
GO:0048661	positive regulation of smooth muscle cell proliferation
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0030155	regulation of cell adhesion
GO:0007165	signal transduction
GO:0003376	sphingolipid signaling pathway

Cellular Component

GO:0009897	external side of plasma membrane
GO:0016021	integral to membrane
GO:0016020	membrane
GO:0005886	plasma membrane

Molecular Function

GO:0004930	G-protein coupled receptor activity
GO:0004871	signal transducer activity
GO:0046625	sphingolipid binding

sphingosine-1-phosphate receptor 1

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function