endothelin receptor type B

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ETb, endothelin receptor type B, Endothelin B receptor precursor, s, ET-B, Sox10m1, ET>B<, AU022549, Ednrb, Endothelin receptor Non-selective type

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:222.30 cerebellum:313.20 brain stem:95.30 corpus callosum/glia:- pineal gland:- peripheral nerve:267.50 spine:141.90 retina:32.10 eye:91.20 artery/aorta:168.80 vein:- lymphnode:- peripheral blood:- spleen:26.30 thymus:9.90 bone marrow:- adipose:- bone:37.60 skin:23.80
GeneChip cerebrum:6.91 cerebellum:7.93 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:7.80 spine:7.84 retina:4.93 eye:5.87 artery/aorta:- vein:8.10 lymphnode:6.11 peripheral blood:- spleen:5.50 thymus:- bone marrow:5.31 adipose:6.44 bone:5.06 skin:5.12
CAGE cerebrum:3.97 cerebellum:- brain stem:4.10 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:4.42 retina:- eye:- artery/aorta:3.74 vein:- lymphnode:3.23 peripheral blood:- spleen:1.22 thymus:0.67 bone marrow:- adipose:- bone:1.51 skin:3.75
RNA-seq cerebrum:3.20 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:43.60 placenta:13.80 prostate:30.90 ovary:23 testis:- heart:111.60 muscle:- esophagus:- stomach:- intestine:- colon:17.60     liver/hepato:-        lung:110.50    bladder:66.20 kidney:56.40 pituitary:77.50 thyroid/parathyroid:112.50 adrenal gland:- pancreas:84.40 breast:13.10 salivary:-
GeneChip uterus:5.62 placenta:7.60 prostate:5.21 ovary:6.07 testis:5.30 heart:6.31 muscle:6.18 esophagus:- stomach:5.96 intestine:6.09 colon:- liver/hepato:5.99 lung:7.55 bladder:5.78 kidney:6.36 pituitary:6.34 thyroid/parathyroid:- adrenal gland:6.30 pancreas:6.20 breast:5.97 salivary:5.56
CAGE uterus:2.26 placenta:3.93 prostate:2.00 ovary:2.98 testis:0 heart:- muscle:- esophagus:- stomach:2.26 intestine:3.26 colon:3.19     liver/hepato:3.18    lung:4.18 bladder:2.92 kidney:- pituitary:3.11 thyroid/parathyroid:- adrenal gland:3.59 pancreas:2.66 breast:2.71 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:1.72 esophagus:- stomach:- intestine:- colon:-     liver/hepato:2.27        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-


Refseq ID NM_001136061
Gene ID 13618
Unigene ID Mm.229532
Probe set ID 1426314_at  [Mouse430_2]
Ensembl ID ENSMUSG00000022122

Orthologous Gene

Human[8]  NM_000115, NM_001122659, NM_001201397, NM_003991
Rat [0]  

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed  (Pubmed ID)

Gene Ontology  (GO ID)

Biological Process

GO:0007200  activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger
GO:0019934  cGMP-mediated signaling
GO:0007204  elevation of cytosolic calcium ion concentration
GO:0048484  enteric nervous system development
GO:0042045  epithelial fluid transport
GO:0007186  G-protein coupled receptor protein signaling pathway
GO:0048246  macrophage chemotaxis
GO:0030318  melanocyte differentiation
GO:0043066  negative regulation of apoptosis
GO:0032269  negative regulation of cellular protein metabolic process
GO:0014043  negative regulation of neuron maturation
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0001755  neural crest cell migration
GO:0007422  peripheral nervous system development
GO:0043473  pigmentation
GO:0048066  pigmentation during development
GO:0008284  positive regulation of cell proliferation
GO:0060406  positive regulation of penile erection
GO:0001934  positive regulation of protein amino acid phosphorylation
GO:0007497  posterior midgut development
GO:0008217  regulation of blood pressure
GO:0050678  regulation of epithelial cell proliferation
GO:0031620  regulation of fever
GO:0006885  regulation of pH
GO:0051930  regulation of sensory perception of pain
GO:0032496  response to lipopolysaccharide
GO:0048265  response to pain
GO:0019233  sensory perception of pain
GO:0007165  signal transduction
GO:0042310  vasoconstriction
GO:0042311  vasodilation
GO:0014826  vein smooth muscle contraction

Cellular Component

GO:0016021  integral to membrane
GO:0016020  membrane
GO:0045121  membrane raft
GO:0031965  nuclear membrane
GO:0005886  plasma membrane

Molecular Function

GO:0004962  endothelin receptor activity
GO:0004930  G-protein coupled receptor activity
GO:0017046  peptide hormone binding
GO:0005515  protein binding
GO:0004871  signal transducer activity
GO:0031702  type 1 angiotensin receptor binding