guanine nucleotide binding protein (G protein), alpha inhibiting 2

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Synonym

Galphai2, Gnai-2, Adenylate cyclase-inhibiting G alpha protein, Gnai2, C76432, Gia

normal 40 tissues
developmental tissues and primary cells（FANTOM5 CAGE）

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:144.10

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:773.40

peripheral nerve:114.70

spine:-

retina:578.60

eye:167.20

artery/aorta:-

vein:-

lymphnode:64.80

peripheral blood:244.40

spleen:144.80

thymus:69.20

bone marrow:192.30

adipose:425.40

bone:313.10

skin:150.40

GeneChip

cerebrum:10.13

cerebellum:9.55

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:10.84

spine:10.59

retina:10.15

eye:10.73

artery/aorta:-

vein:10.69

lymphnode:11.42

peripheral blood:-

spleen:11.75

thymus:-

bone marrow:11.63

adipose:10.40

bone:11.69

skin:9.96

CAGE

cerebrum:5.16

cerebellum:-

brain stem:5.57

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:5.65

retina:-

eye:-

artery/aorta:5.73

vein:-

lymphnode:6.46

peripheral blood:-

spleen:6.26

thymus:6.26

bone marrow:-

adipose:-

bone:6.97

skin:5.50

RNA-seq

cerebrum:54.34

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:174.50

placenta:262.30

prostate:185.30

ovary:137.90

testis:36.90

heart:130.20

muscle:426.10

esophagus:-

stomach:32.70

intestine:-

colon:334.80

liver/hepato:117.70

lung:281.20

bladder:-

kidney:120.90

pituitary:452.10

thyroid/parathyroid:337.40

adrenal gland:-

pancreas:215.80

breast:528.90

salivary:270

GeneChip

uterus:11.23

placenta:10.81

prostate:10.59

ovary:11.08

testis:9.35

heart:11.16

muscle:10.29

esophagus:-

stomach:10.36

intestine:10.63

colon:-

liver/hepato:9.87

lung:11.78

bladder:10.94

kidney:10.06

pituitary:10.95

thyroid/parathyroid:-

adrenal gland:10.71

pancreas:9.70

breast:10.54

salivary:9.76

CAGE

uterus:6.02

placenta:5.97

prostate:5.58

ovary:5.74

testis:4.65

heart:-

muscle:-

esophagus:-

stomach:5.66

intestine:5.73

colon:5.77

liver/hepato:5.11

lung:6.38

bladder:5.96

kidney:-

pituitary:5.58

thyroid/parathyroid:-

adrenal gland:5.61

pancreas:4.91

breast:5.29

salivary:-

RNA-seq

uterus:-

placenta:-

prostate:-

ovary:-

testis:-

heart:-

muscle:24.75

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:13.71

lung:-

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

IDs

Refseq ID	NM_008138
Gene ID	14678
Unigene ID	Mm.196464
Probe set ID	1435652_a_at [Mouse430_2]
Ensembl ID	ENSMUSG00000032562

Orthologous Gene

Human[2]	NM_001166425, NM_002070
Rat [0]

Chromosomal Region

Gene Family (Interpro ID)

IPR001408	G-protein alpha subunit, group I
IPR001019	Guanine nucleotide binding protein (G-protein), alpha subunit

Gene Ontology (GO ID)

Biological Process

GO:0000186	activation of MAPKK activity
GO:0001973	adenosine receptor signaling pathway
GO:0007049	cell cycle
GO:0051301	cell division
GO:0008283	cell proliferation
GO:0007186	G-protein coupled receptor protein signaling pathway
GO:0007188	G-protein signaling, coupled to cAMP nucleotide second messenger
GO:0007214	gamma-aminobutyric acid signaling pathway
GO:0006184	GTP catabolic process
GO:0007193	inhibition of adenylate cyclase activity by G-protein signaling pathway
GO:0007213	muscarinic acetylcholine receptor signaling pathway
GO:0050805	negative regulation of synaptic transmission
GO:0008284	positive regulation of cell proliferation
GO:0007243	protein kinase cascade
GO:0051924	regulation of calcium ion transport
GO:0008016	regulation of heart contraction
GO:0007165	signal transduction

Cellular Component

GO:0005813	centrosome
GO:0005737	cytoplasm
GO:0005856	cytoskeleton
GO:0005829	cytosol
GO:0031234	extrinsic to internal side of plasma membrane
GO:0005834	heterotrimeric G-protein complex
GO:0016020	membrane
GO:0045121	membrane raft
GO:0030496	midbody
GO:0005634	nucleus
GO:0005886	plasma membrane

Molecular Function

GO:0031683	G-protein beta/gamma-subunit binding
GO:0001664	G-protein-coupled receptor binding
GO:0005525	GTP binding
GO:0003924	GTPase activity
GO:0019001	guanyl nucleotide binding
GO:0046872	metal ion binding
GO:0000166	nucleotide binding
GO:0005515	protein binding
GO:0004871	signal transducer activity

guanine nucleotide binding protein (G protein), alpha inhibiting 2

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function