G protein-coupled receptor 56

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Synonym

Cyt28, Gpr56, G-protein coupled receptor 56 precursor, TM7LN4, G protein-coupled receptor 56, Serpentine receptor cyt28, TM7XN1

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:133.70 cerebellum:92.10 brain stem:127.10 corpus callosum/glia:- pineal gland:515.60 peripheral nerve:191.10 spine:47.30 retina:96.40 eye:152 artery/aorta:- vein:- lymphnode:- peripheral blood:1092.60 spleen:92.20 thymus:59.30 bone marrow:12.80 adipose:- bone:37.60 skin:221.70
GeneChip cerebrum:7.91 cerebellum:7.19 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:8.50 spine:8.56 retina:5.40 eye:6.03 artery/aorta:- vein:5.51 lymphnode:6.08 peripheral blood:- spleen:6.19 thymus:- bone marrow:8.17 adipose:8.27 bone:7.59 skin:7.32
CAGE cerebrum:3.87 cerebellum:- brain stem:4.60 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:4.93 retina:- eye:- artery/aorta:4.49 vein:- lymphnode:3.62 peripheral blood:- spleen:4.04 thymus:3.89 bone marrow:- adipose:- bone:4.27 skin:5.20
RNA-seq cerebrum:11.77 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:43.60 placenta:82.80 prostate:- ovary:126.40 testis:73.90 heart:37.20 muscle:- esophagus:- stomach:- intestine:37 colon:123.40     liver/hepato:18.10        lung:90.40    bladder:198.50 kidney:201.50 pituitary:103.30 thyroid/parathyroid:- adrenal gland:- pancreas:150.10 breast:94.70 salivary:54
GeneChip uterus:7.73 placenta:8.93 prostate:8.16 ovary:8.37 testis:7.20 heart:7.65 muscle:7.35 esophagus:- stomach:8.10 intestine:7.09 colon:- liver/hepato:5.93 lung:8.28 bladder:7.43 kidney:9.42 pituitary:7.55 thyroid/parathyroid:- adrenal gland:7.29 pancreas:7.80 breast:7.71 salivary:8.61
CAGE uterus:4.33 placenta:5.04 prostate:4.02 ovary:4.35 testis:2.64 heart:- muscle:- esophagus:- stomach:4.46 intestine:3.13 colon:3.15     liver/hepato:2.20    lung:4.79 bladder:4.44 kidney:- pituitary:3.80 thyroid/parathyroid:- adrenal gland:3.89 pancreas:4.19 breast:4.95 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:2.97 esophagus:- stomach:- intestine:- colon:-     liver/hepato:1.98        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_018882
Gene ID 14766
Unigene ID Mm.290834
Probe set ID 1433485_x_at  [Mouse430_2]
Ensembl ID ENSMUSG00000031785

Orthologous Gene

Human[16]  NM_001145770, NM_001145771, NM_001145772, NM_001145773, NM_001145774, NM_005682, NM_201524, NM_201525
Rat[1]  NM_152242, NM_001145771, NM_001145772, NM_001145773, NM_001145774, NM_005682, NM_201524, NM_201525

Chromosomal Region

-

Gene Family (Interpro ID)

IPR000832  GPCR, family 2, secretin-like
IPR017981  GPCR, family 2-like

Link to Pubmed  (Pubmed ID)

8889548
10049584
10349636
10834841
10922068
11042159
11076861
11217851
11438738
12466851
12477932
14610273
15044805
15226823
15489334
15782199
16141072
16141073
16757564
16888225
17008357
17283064
17576745
17932623
18378689
18509043
19243017
19515912
19906978
20981830
21267068
21349848
21724588
21768377
22151329
22333914
22351047
23478665
23874761
24356421

Gene Ontology  (GO ID)

Biological Process

GO:0001525  angiogenesis
GO:0007420  brain development
GO:0007166  cell surface receptor linked signal transduction
GO:0021801  cerebral cortex radial glia guided migration
GO:0007186  G-protein coupled receptor protein signaling pathway
GO:0021819  layer formation in the cerebral cortex
GO:0008285  negative regulation of cell proliferation
GO:0007218  neuropeptide signaling pathway
GO:0045785  positive regulation of cell adhesion
GO:0035025  positive regulation of Rho protein signal transduction
GO:0070528  protein kinase C signaling cascade
GO:0007266  Rho protein signal transduction
GO:0007165  signal transduction
GO:0010573  vascular endothelial growth factor production

Cellular Component

GO:0016021  integral to membrane
GO:0016020  membrane
GO:0005886  plasma membrane

Molecular Function

GO:0005518  collagen binding
GO:0050840  extracellular matrix binding
GO:0004930  G-protein coupled receptor activity
GO:0004871  signal transducer activity
GO:0004888  transmembrane receptor activity