glutathione peroxidase 1

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Synonym

glutathione peroxidase 1, GSHPx-1, cellular GPx, Gpx, Cellular glutathione peroxidase, GPx-1, Gpx1, CGPx, AI195024, Glutathione peroxidase 1, AL033363

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:- cerebellum:18.40 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip cerebrum:10.59 cerebellum:10.24 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:11.65 spine:10.55 retina:8.48 eye:9.81 artery/aorta:- vein:13.07 lymphnode:12.63 peripheral blood:- spleen:13.06 thymus:- bone marrow:14.40 adipose:12.79 bone:14.20 skin:11.95
CAGE cerebrum:0.10 cerebellum:- brain stem:0.23 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:0.66 retina:- eye:- artery/aorta:0.54 vein:- lymphnode:0.71 peripheral blood:- spleen:0.79 thymus:0.27 bone marrow:- adipose:- bone:1.30 skin:0.51
RNA-seq cerebrum:61.89 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:7.40 heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:13.10 placenta:12.31 prostate:12.20 ovary:12.51 testis:8.95 heart:11.05 muscle:11.07 esophagus:- stomach:12.53 intestine:12.25 colon:- liver/hepato:14.30 lung:12.55 bladder:12.23 kidney:14.35 pituitary:10.58 thyroid/parathyroid:- adrenal gland:12.04 pancreas:11.22 breast:12.07 salivary:12.18
CAGE uterus:1.27 placenta:0.67 prostate:0.20 ovary:0.88 testis:0 heart:- muscle:- esophagus:- stomach:0 intestine:0 colon:0     liver/hepato:0.78    lung:0.31 bladder:0.46 kidney:- pituitary:0 thyroid/parathyroid:- adrenal gland:0.56 pancreas:0 breast:0.12 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:32.13 esophagus:- stomach:- intestine:- colon:-     liver/hepato:549.13        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

IDs

Refseq ID NM_008160
Gene ID 14775
Unigene ID Mm.109021
Probe set ID 1460671_at  [Mouse430_2]
Ensembl ID ENSMUSG00000063856

Orthologous Gene

Human[2]  NM_000581, NM_201397
Rat[2]  NM_000581, NM_201397

Chromosomal Region

-

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

Gene Ontology  (GO ID)

Biological Process

GO:0060055  angiogenesis involved in wound healing
GO:0006915  apoptosis
GO:0043534  blood vessel endothelial cell migration
GO:0008283  cell proliferation
GO:0045454  cell redox homeostasis
GO:0001885  endothelial cell development
GO:0045444  fat cell differentiation
GO:0006749  glutathione metabolic process
GO:0060047  heart contraction
GO:0042744  hydrogen peroxide catabolic process
GO:0008631  induction of apoptosis by oxidative stress
GO:0051702  interaction with symbiont
GO:0006629  lipid metabolic process
GO:0051450  myoblast proliferation
GO:0014902  myotube differentiation
GO:0043066  negative regulation of apoptosis
GO:0043154  negative regulation of caspase activity
GO:0002862  negative regulation of inflammatory response to antigenic stimulus
GO:0090201  negative regulation of release of cytochrome c from mitochondria
GO:0055114  oxidation reduction
GO:0051897  positive regulation of protein kinase B signaling cascade
GO:0018158  protein amino acid oxidation
GO:0040029  regulation of gene expression, epigenetic
GO:0033599  regulation of mammary gland epithelial cell proliferation
GO:0043523  regulation of neuron apoptosis
GO:0010332  response to gamma radiation
GO:0042542  response to hydrogen peroxide
GO:0033194  response to hydroperoxide
GO:0006982  response to lipid hydroperoxide
GO:0006979  response to oxidative stress
GO:0000302  response to reactive oxygen species
GO:0010269  response to selenium ion
GO:0009609  response to symbiotic bacterium
GO:0009636  response to toxin
GO:0009611  response to wounding
GO:0009410  response to xenobiotic stimulus
GO:0007605  sensory perception of sound
GO:0048741  skeletal muscle fiber development
GO:0043403  skeletal muscle tissue regeneration
GO:0001659  temperature homeostasis
GO:0006641  triglyceride metabolic process
GO:0009650  UV protection
GO:0042311  vasodilation

Cellular Component

GO:0005737  cytoplasm
GO:0005739  mitochondrion
GO:0005634  nucleus

Molecular Function

GO:0004866  endopeptidase inhibitor activity
GO:0043295  glutathione binding
GO:0004602  glutathione peroxidase activity
GO:0016491  oxidoreductase activity
GO:0004601  peroxidase activity
GO:0047066  phospholipid-hydroperoxide glutathione peroxidase activity
GO:0005515  protein binding
GO:0008430  selenium binding
GO:0017124  SH3 domain binding