hematopoietically expressed homeobox

Synonym

Hhex, Homeobox protein HEX, Homeobox protein PRH, Prh, Hex, Prhx, Hematopoietically expressed homeobox, hematopoietically expressed homeobox

normal 40 tissues
developmental tissues and primary cells（FANTOM5 CAGE）

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:3.50

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:38.20

spine:-

retina:32.10

eye:-

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:14.40

spleen:105.30

thymus:-

bone marrow:89.80

adipose:-

bone:-

skin:-

GeneChip

cerebrum:5.13

cerebellum:4.66

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:4.87

spine:5.10

retina:5.14

eye:5.64

artery/aorta:-

vein:6.44

lymphnode:9.40

peripheral blood:-

spleen:9.62

thymus:-

bone marrow:9.04

adipose:5.66

bone:8.88

skin:5.42

CAGE

cerebrum:1.08

cerebellum:-

brain stem:1.23

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:1.42

retina:-

eye:-

artery/aorta:2.19

vein:-

lymphnode:4.24

peripheral blood:-

spleen:3.70

thymus:1.06

bone marrow:-

adipose:-

bone:4.14

skin:1.89

RNA-seq

cerebrum:0.99

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:-

placenta:-

prostate:-

ovary:34.50

testis:-

heart:37.20

muscle:-

esophagus:-

stomach:-

intestine:-

colon:35.20

liver/hepato:126.70

lung:-

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:424.40

pancreas:-

breast:6.50

salivary:-

GeneChip

uterus:6.22

placenta:5.47

prostate:4.97

ovary:5.75

testis:5.35

heart:6.10

muscle:5.66

esophagus:-

stomach:5.33

intestine:5.33

colon:-

liver/hepato:10.53

lung:7.61

bladder:5.66

kidney:5.22

pituitary:4.74

thyroid/parathyroid:-

adrenal gland:9.71

pancreas:6.59

breast:6.34

salivary:5.15

CAGE

uterus:2.00

placenta:1.48

prostate:0.84

ovary:2.04

testis:0.45

heart:-

muscle:-

esophagus:-

stomach:1.35

intestine:0.72

colon:1.03

liver/hepato:5.15

lung:3.28

bladder:2.02

kidney:-

pituitary:0.70

thyroid/parathyroid:-

adrenal gland:4.98

pancreas:2.75

breast:1.76

salivary:-

RNA-seq

uterus:-

placenta:-

prostate:-

ovary:-

testis:-

heart:-

muscle:2.05

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:11.67

lung:-

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

IDs

Refseq ID	NM_008245
Gene ID	15242
Unigene ID	Mm.33896
Probe set ID	1423319_at [Mouse430_2]
Ensembl ID	ENSMUSG00000024986

Orthologous Gene

Human[2]	NM_002729
Rat[1]	NM_024385

Chromosomal Region

Gene Family (Interpro ID)

IPR001356	Homeobox
IPR009057	Homeodomain-like
IPR012287	Homeodomain-related

Gene Ontology (GO ID)

Biological Process

GO:0009952	anterior/posterior pattern formation
GO:0030183	B cell differentiation
GO:0007049	cell cycle
GO:0030154	cell differentiation
GO:0008283	cell proliferation
GO:0071103	DNA conformation change
GO:0035050	embryonic heart tube development
GO:0048568	embryonic organ development
GO:0007492	endoderm development
GO:0030900	forebrain development
GO:0048853	forebrain morphogenesis
GO:0030097	hemopoiesis
GO:0070365	hepatocyte differentiation
GO:0001701	in utero embryonic development
GO:0022027	interkinetic nuclear migration
GO:0001889	liver development
GO:0002009	morphogenesis of an epithelium
GO:0006406	mRNA export from nucleus
GO:0035264	multicellular organism growth
GO:0007275	multicellular organismal development
GO:0002573	myeloid leukocyte differentiation
GO:0016525	negative regulation of angiogenesis
GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0045892	negative regulation of transcription, DNA-dependent
GO:0030948	negative regulation of vascular endothelial growth factor receptor signaling pathway
GO:0009887	organ morphogenesis
GO:0031016	pancreas development
GO:0016973	poly(A)+ mRNA export from nucleus
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0030177	positive regulation of Wnt receptor signaling pathway
GO:0060431	primary lung bud formation
GO:0090009	primitive streak formation
GO:0034504	protein localization in nucleus
GO:0042127	regulation of cell proliferation
GO:0006357	regulation of transcription from RNA polymerase II promoter
GO:0006355	regulation of transcription, DNA-dependent
GO:0007165	signal transduction
GO:0030878	thyroid gland development
GO:0048729	tissue morphogenesis
GO:0006351	transcription, DNA-dependent
GO:0001570	vasculogenesis
GO:0016055	Wnt receptor signaling pathway

Cellular Component

GO:0005737	cytoplasm
GO:0005634	nucleus
GO:0032993	protein-DNA complex

Molecular Function

GO:0003682	chromatin binding
GO:0008301	DNA bending activity
GO:0003677	DNA binding
GO:0044212	DNA regulatory region binding
GO:0008190	eukaryotic initiation factor 4E binding
GO:0042803	protein homodimerization activity
GO:0043565	sequence-specific DNA binding
GO:0003700	transcription factor activity
GO:0008134	transcription factor binding
GO:0070491	transcription repressor binding

hematopoietically expressed homeobox

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function