nuclear receptor subfamily 4, group A, member 1

Synonym

N10, Hbr1, Nuclear hormone receptor NUR/77, NP10, nur77, GFRP1, NGFIB, Orphan nuclear receptor NR4A1, Hbr-1, nuclear receptor subfamily 4, group A, member 1, Nur77, Nr4a1, Gfrp, Orphan nuclear receptor HMR, Hmr, N10 nuclear protein, NGFI-B, TIS1

normal 40 tissues
developmental tissues and primary cells（FANTOM5 CAGE）

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:3.50

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

GeneChip

cerebrum:10.22

cerebellum:8.97

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:9.01

spine:7.99

retina:7.46

eye:7.42

artery/aorta:-

vein:7.47

lymphnode:8.32

peripheral blood:-

spleen:9.17

thymus:-

bone marrow:7.41

adipose:9.23

bone:7.88

skin:7.99

CAGE

cerebrum:3.31

cerebellum:-

brain stem:2.50

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:2.19

retina:-

eye:-

artery/aorta:4.63

vein:-

lymphnode:4.34

peripheral blood:-

spleen:2.56

thymus:3.78

bone marrow:-

adipose:-

bone:2.66

skin:3.32

RNA-seq

cerebrum:9.70

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:-

placenta:-

prostate:-

ovary:-

testis:-

heart:-

muscle:-

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:-

lung:-

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

GeneChip

uterus:7.07

placenta:7.40

prostate:8.56

ovary:8.52

testis:8.79

heart:9.32

muscle:11.73

esophagus:-

stomach:7.65

intestine:7.77

colon:-

liver/hepato:6.72

lung:8.84

bladder:10.71

kidney:7.71

pituitary:11.56

thyroid/parathyroid:-

adrenal gland:12.88

pancreas:7.94

breast:9.30

salivary:9.73

CAGE

uterus:2.12

placenta:1.53

prostate:3.68

ovary:3.62

testis:1.71

heart:-

muscle:-

esophagus:-

stomach:2.73

intestine:1.60

colon:1.81

liver/hepato:0

lung:3.56

bladder:3.48

kidney:-

pituitary:5.27

thyroid/parathyroid:-

adrenal gland:6.06

pancreas:1.84

breast:1.58

salivary:-

RNA-seq

uterus:-

placenta:-

prostate:-

ovary:-

testis:-

heart:-

muscle:24.48

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:1.01

lung:-

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

IDs

Refseq ID	NM_010444
Gene ID	15370
Unigene ID	Mm.119000
Probe set ID	1416505_at [Mouse430_2]
Ensembl ID	ENSMUSG00000023034

Orthologous Gene

Human[2]	NM_001202233, NM_002135, NM_173157
Rat [0]

Chromosomal Region

Gene Family (Interpro ID)

IPR003070	Orphan nuclear receptor
IPR003071	Orphan nuclear receptor, HMR type
IPR001723	Steroid hormone receptor
IPR013088	Zinc finger, NHR/GATA-type
IPR001628	Zinc finger, nuclear hormone receptor-type

Gene Ontology (GO ID)

Biological Process

GO:0006915	apoptosis
GO:0002042	cell migration involved in sprouting angiogenesis
GO:0071310	cellular response to organic substance
GO:0030522	intracellular receptor-mediated signaling pathway
GO:0043154	negative regulation of caspase activity
GO:0043065	positive regulation of apoptosis
GO:0001938	positive regulation of endothelial cell proliferation
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0045893	positive regulation of transcription, DNA-dependent
GO:0006355	regulation of transcription, DNA-dependent
GO:0010035	response to inorganic substance
GO:0043401	steroid hormone mediated signaling pathway
GO:0006351	transcription, DNA-dependent

Cellular Component

GO:0005634	nucleus
GO:0005667	transcription factor complex

Molecular Function

GO:0003677	DNA binding
GO:0004879	ligand-dependent nuclear receptor activity
GO:0046872	metal ion binding
GO:0005515	protein binding
GO:0046982	protein heterodimerization activity
GO:0042803	protein homodimerization activity
GO:0043565	sequence-specific DNA binding
GO:0003707	steroid hormone receptor activity
GO:0003700	transcription factor activity
GO:0008270	zinc ion binding

nuclear receptor subfamily 4, group A, member 1

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function