heat shock protein 90, alpha (cytosolic), class A member 1

Synonym

Hspca, hsp4, HSP 86, Hsp90aa1, TSTA, AL024080, Hsp86, AL024147, Hsp89, Hsp86-1, 89kDa, Tumor-specific transplantation 86 kDa antigen, Heat shock protein HSP 90-alpha

normal 40 tissues
developmental tissues and primary cells（FANTOM5 CAGE）

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:387.30

cerebellum:202.60

brain stem:158.90

corpus callosum/glia:-

pineal gland:257.80

peripheral nerve:152.90

spine:94.60

retina:353.60

eye:235.50

artery/aorta:84.40

vein:-

lymphnode:10.80

peripheral blood:460.10

spleen:276.50

thymus:49.40

bone marrow:538.50

adipose:-

bone:150.30

skin:142.50

GeneChip

cerebrum:13.01

cerebellum:13.17

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:13.74

spine:13.25

retina:12.28

eye:11

artery/aorta:-

vein:11.84

lymphnode:11.66

peripheral blood:-

spleen:12.24

thymus:-

bone marrow:12.48

adipose:11.28

bone:12.33

skin:11.24

CAGE

cerebrum:4.27

cerebellum:-

brain stem:4.47

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:4.67

retina:-

eye:-

artery/aorta:2.21

vein:-

lymphnode:2.60

peripheral blood:-

spleen:2.55

thymus:1.75

bone marrow:-

adipose:-

bone:2.37

skin:1.98

RNA-seq

cerebrum:83.76

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:523.50

placenta:1311.70

prostate:61.80

ovary:597.50

testis:1182.30

heart:409.20

muscle:284.10

esophagus:-

stomach:916.40

intestine:1331

colon:264.30

liver/hepato:244.40

lung:241

bladder:132.40

kidney:548

pituitary:1563

thyroid/parathyroid:-

adrenal gland:424.40

pancreas:75.10

breast:71.80

salivary:-

GeneChip

uterus:11.73

placenta:12.43

prostate:11.44

ovary:12.24

testis:13.30

heart:11.22

muscle:10.64

esophagus:-

stomach:12.23

intestine:12.17

colon:-

liver/hepato:12.05

lung:12.78

bladder:11.93

kidney:12.44

pituitary:12.74

thyroid/parathyroid:-

adrenal gland:12.23

pancreas:11.44

breast:11.10

salivary:10.64

CAGE

uterus:1.69

placenta:3.15

prostate:2.31

ovary:2.21

testis:6.97

heart:-

muscle:-

esophagus:-

stomach:1.75

intestine:1.65

colon:1.77

liver/hepato:1.64

lung:1.85

bladder:2.37

kidney:-

pituitary:2.61

thyroid/parathyroid:-

adrenal gland:2.22

pancreas:2.19

breast:1.69

salivary:-

RNA-seq

uterus:-

placenta:-

prostate:-

ovary:-

testis:-

heart:-

muscle:12.97

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:25.82

lung:-

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

IDs

Refseq ID	NM_010480
Gene ID	15519
Unigene ID	Mm.341186
Probe set ID	1426645_at [Mouse430_2]
Ensembl ID	ENSMUSG00000021270

Orthologous Gene

Human[16]	NM_001017963, NM_005348
Rat[16]	NM_001017963, NM_005348

Chromosomal Region

Gene Family (Interpro ID)

IPR003594	ATPase-like, ATP-binding domain
IPR001404	Chaperone protein htpG
IPR020575	Heat shock protein Hsp90, N-terminal

Gene Ontology (GO ID)

Biological Process

GO:0006200	ATP catabolic process
GO:0051131	chaperone-mediated protein complex assembly
GO:0001764	neuron migration
GO:0006809	nitric oxide biosynthetic process
GO:0045793	positive regulation of cell size
GO:0045585	positive regulation of cytotoxic T cell differentiation
GO:0010592	positive regulation of lamellipodium assembly
GO:0045429	positive regulation of nitric oxide biosynthetic process
GO:0033160	positive regulation of protein import into nucleus, translocation
GO:0006457	protein folding
GO:0045040	protein import into mitochondrial outer membrane
GO:0042026	protein refolding
GO:0006950	response to stress
GO:0006986	response to unfolded protein

Cellular Component

GO:0016324	apical plasma membrane
GO:0016323	basolateral plasma membrane
GO:0031526	brush border membrane
GO:0043025	cell soma
GO:0009986	cell surface
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0031012	extracellular matrix
GO:0005622	intracellular
GO:0043005	neuron projection
GO:0048471	perinuclear region of cytoplasm
GO:0043234	protein complex

Molecular Function

GO:0005524	ATP binding
GO:0016887	ATPase activity
GO:0002135	CTP binding
GO:0032564	dATP binding
GO:0005525	GTP binding
GO:0042802	identical protein binding
GO:0003729	mRNA binding
GO:0030235	nitric-oxide synthase regulator activity
GO:0000166	nucleotide binding
GO:0005515	protein binding
GO:0042803	protein homodimerization activity
GO:0019901	protein kinase binding
GO:0019903	protein phosphatase binding
GO:0017098	sulfonylurea receptor binding
GO:0030911	TPR domain binding
GO:0051082	unfolded protein binding
GO:0002134	UTP binding

heat shock protein 90, alpha (cytosolic), class A member 1

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function