5-hydroxytryptamine (serotonin) receptor 2A

Synonym

E030013E04, 5-HT-2A, 5-hydroxytryptamine 2A receptor, Htr2, 5-hydroxytryptamine (serotonin) receptor 2A, 5-HT-2, Serotonin receptor 2A, MGC124302, MGC124301, Htr2a, 5-HT2A receptor, Htr-2

normal 40 tissues
developmental tissues and primary cells（FANTOM5 CAGE）

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:5.20

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:19.10

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:97.20

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

GeneChip

nodata

CAGE

cerebrum:0.60

cerebellum:-

brain stem:1.10

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:1.28

retina:-

eye:-

artery/aorta:1.06

vein:-

lymphnode:0.23

peripheral blood:-

spleen:0.79

thymus:0

bone marrow:-

adipose:-

bone:0.63

skin:0.40

RNA-seq

cerebrum:1.45

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:-

placenta:-

prostate:-

ovary:-

testis:-

heart:-

muscle:-

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:-

lung:20.10

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

GeneChip

nodata

CAGE

uterus:1.22

placenta:0.29

prostate:0.20

ovary:0.76

testis:0

heart:-

muscle:-

esophagus:-

stomach:0

intestine:0

colon:0

liver/hepato:0

lung:0.75

bladder:0.77

kidney:-

pituitary:0

thyroid/parathyroid:-

adrenal gland:0.26

pancreas:0

breast:0.12

salivary:-

RNA-seq

uterus:-

placenta:-

prostate:-

ovary:-

testis:-

heart:-

muscle:1.32

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:0

lung:-

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

IDs

Refseq ID	NM_172812
Gene ID	15558
Unigene ID	Mm.214351
Probe set ID	-
Ensembl ID	ENSMUSG00000034997

Orthologous Gene

Human[4]	NM_000621, NM_001165947
Rat [0]

Chromosomal Region

14D3 [75,040,647 - 75,106,666]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR000455	5-Hydroxytryptamine 2A receptor
IPR002231	5-Hydroxytryptamine receptor
IPR000276	7TM GPCR, rhodopsin-like
IPR017452	GPCR, rhodopsin-like superfamily

Gene Ontology (GO ID)

Biological Process

GO:0007208	activation of phospholipase C activity by serotonin receptor signaling pathway
GO:0008219	cell death
GO:0070371	ERK1 and ERK2 cascade
GO:0007186	G-protein coupled receptor protein signaling pathway
GO:0007613	memory
GO:0043267	negative regulation of potassium ion transport
GO:0051967	negative regulation of synaptic transmission, glutamatergic
GO:0006661	phosphatidylinositol biosynthetic process
GO:0014065	phosphoinositide 3-kinase cascade
GO:0008284	positive regulation of cell proliferation
GO:0043406	positive regulation of MAP kinase activity
GO:0045907	positive regulation of vasoconstriction
GO:0050795	regulation of behavior
GO:0014059	regulation of dopamine secretion
GO:0046883	regulation of hormone secretion
GO:0051209	release of sequestered calcium ion into cytosol
GO:0042493	response to drug
GO:0006950	response to stress
GO:0019233	sensory perception of pain
GO:0007210	serotonin receptor signaling pathway
GO:0007165	signal transduction
GO:0030431	sleep
GO:0006939	smooth muscle contraction
GO:0001659	temperature homeostasis

Cellular Component

GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0030425	dendrite
GO:0043198	dendritic shaft
GO:0016021	integral to membrane
GO:0005887	integral to plasma membrane
GO:0016020	membrane
GO:0005886	plasma membrane

Molecular Function

GO:0008144	drug binding
GO:0001965	G-protein alpha-subunit binding
GO:0004930	G-protein coupled receptor activity
GO:0004435	phosphoinositide phospholipase C activity
GO:0032403	protein complex binding
GO:0051378	serotonin binding
GO:0004993	serotonin receptor activity
GO:0004871	signal transducer activity

5-hydroxytryptamine (serotonin) receptor 2A

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function