interleukin 1 receptor antagonist

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Synonym

IL1 inhibitor, IRAP, IL-1RN, IL-1ra, Il1rn, interleukin 1 receptor antagonist, F630041P17Rik, Il-1ra

normal 40 tissues
developmental tissues and primary cells（FANTOM5 CAGE）

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:109.40

cerebellum:-

brain stem:31.80

corpus callosum/glia:-

pineal gland:257.80

peripheral nerve:95.50

spine:-

retina:353.60

eye:98.80

artery/aorta:-

vein:-

lymphnode:32.40

peripheral blood:86.30

spleen:65.80

thymus:98.80

bone marrow:307.70

adipose:-

bone:450.90

skin:102.90

GeneChip

cerebrum:4.57

cerebellum:4.80

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:4.62

spine:4.73

retina:4.86

eye:5.22

artery/aorta:-

vein:5.02

lymphnode:4.92

peripheral blood:-

spleen:4.88

thymus:-

bone marrow:5.50

adipose:4.88

bone:5.41

skin:6

CAGE

cerebrum:0

cerebellum:-

brain stem:0

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:0.32

retina:-

eye:-

artery/aorta:2.25

vein:-

lymphnode:3.75

peripheral blood:-

spleen:1.78

thymus:1.95

bone marrow:-

adipose:-

bone:3.44

skin:4.38

RNA-seq

cerebrum:0.17

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:305.40

placenta:179.50

prostate:-

ovary:298.80

testis:88.70

heart:186

muscle:284.10

esophagus:-

stomach:65.50

intestine:295.80

colon:105.70

liver/hepato:172

lung:512.10

bladder:-

kidney:201.50

pituitary:335.80

thyroid/parathyroid:562.40

adrenal gland:-

pancreas:18.80

breast:212.20

salivary:162

GeneChip

uterus:4.78

placenta:5

prostate:4.70

ovary:4.30

testis:5.12

heart:4.98

muscle:4.70

esophagus:-

stomach:5.62

intestine:5.21

colon:-

liver/hepato:5.21

lung:5.08

bladder:5.07

kidney:4.83

pituitary:4.74

thyroid/parathyroid:-

adrenal gland:4.55

pancreas:4.80

breast:4.89

salivary:5.04

CAGE

uterus:1.32

placenta:2.03

prostate:0

ovary:1.35

testis:0

heart:-

muscle:-

esophagus:-

stomach:3.62

intestine:0.84

colon:1.81

liver/hepato:1.45

lung:2.54

bladder:2.14

kidney:-

pituitary:0

thyroid/parathyroid:-

adrenal gland:2.34

pancreas:0

breast:1.35

salivary:-

RNA-seq

uterus:-

placenta:-

prostate:-

ovary:-

testis:-

heart:-

muscle:1.32

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:1.68

lung:-

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

IDs

Refseq ID	NM_001039701
Gene ID	16181
Unigene ID	Mm.88216
Probe set ID	1425663_at [Mouse430_2]
Ensembl ID	ENSMUSG00000026981

Orthologous Gene

Human[13]	NM_000577, NM_173841, NM_173842, NM_173843
Rat[1]	NM_022194, NM_173841, NM_173842, NM_173843

Chromosomal Region

2A3 [24,192,373 - 24,207,014]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR008996	Cytokine, IL-1-like
IPR000975	Interleukin-1
IPR003297	Interleukin-1 receptor antagonist IL1RA
IPR003294	Interleukin-1, alpha/beta

Gene Ontology (GO ID)

Biological Process

GO:0006953	acute-phase response
GO:0001660	fever
GO:0030073	insulin secretion
GO:0006629	lipid metabolic process
GO:0007613	memory
GO:0043066	negative regulation of apoptosis
GO:0030336	negative regulation of cell migration
GO:0001960	negative regulation of cytokine-mediated signaling pathway
GO:0014050	negative regulation of glutamate secretion
GO:0034115	negative regulation of heterotypic cell-cell adhesion
GO:0045837	negative regulation of membrane potential
GO:0043507	positive regulation of JUN kinase activity
GO:0051384	response to glucocorticoid stimulus

Cellular Component

GO:0005813	centrosome
GO:0005737	cytoplasm
GO:0005576	extracellular region
GO:0005615	extracellular space
GO:0005634	nucleus
GO:0031982	vesicle

Molecular Function

GO:0005152	interleukin-1 receptor antagonist activity
GO:0005149	interleukin-1 receptor binding
GO:0045352	interleukin-1 Type I receptor antagonist activity
GO:0045353	interleukin-1 Type II receptor antagonist activity
GO:0005150	interleukin-1, Type I receptor binding
GO:0005151	interleukin-1, Type II receptor binding

interleukin 1 receptor antagonist

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function