potassium large conductance calcium-activated channel, subfamily M, alpha member 1

Synonym

BK channel alpha subunit, mSlo, BKCA alpha, mSlo1, Kcnma, MaxiK, Slo homolog, Slo1, Maxi K channel, Slowpoke homolog, K(VCA)alpha, Slo-alpha, KCa1.1, Kcnma1, BK channel, Slo

normal 40 tissues
developmental tissues and primary cells（FANTOM5 CAGE）

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:-

cerebellum:-

brain stem:31.80

corpus callosum/glia:-

pineal gland:-

peripheral nerve:19.10

spine:-

retina:32.10

eye:15.20

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:26.30

thymus:-

bone marrow:-

adipose:-

bone:12.50

skin:7.90

GeneChip

cerebrum:7.52

cerebellum:6.44

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:5.54

spine:6.05

retina:5.87

eye:4.53

artery/aorta:-

vein:4.04

lymphnode:3.99

peripheral blood:-

spleen:3.89

thymus:-

bone marrow:3.88

adipose:3.90

bone:3.99

skin:3.87

CAGE

cerebrum:3.97

cerebellum:-

brain stem:3.28

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:2.76

retina:-

eye:-

artery/aorta:2.07

vein:-

lymphnode:1.35

peripheral blood:-

spleen:0

thymus:1.26

bone marrow:-

adipose:-

bone:2.29

skin:1.63

RNA-seq

cerebrum:4.95

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:-

placenta:-

prostate:-

ovary:-

testis:-

heart:-

muscle:35.50

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:-

lung:-

bladder:198.50

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:6.50

salivary:-

GeneChip

uterus:3.78

placenta:3.85

prostate:5.18

ovary:4.28

testis:3.95

heart:4.06

muscle:5.64

esophagus:-

stomach:4.14

intestine:4.19

colon:-

liver/hepato:3.95

lung:3.85

bladder:4.68

kidney:4.06

pituitary:4.53

thyroid/parathyroid:-

adrenal gland:5.35

pancreas:4.39

breast:4.27

salivary:5.01

CAGE

uterus:2.35

placenta:0.11

prostate:2.52

ovary:3.11

testis:0.45

heart:-

muscle:-

esophagus:-

stomach:1.91

intestine:1.49

colon:1.89

liver/hepato:0.26

lung:0.55

bladder:3.53

kidney:-

pituitary:3.60

thyroid/parathyroid:-

adrenal gland:4.10

pancreas:0

breast:0.78

salivary:-

RNA-seq

uterus:-

placenta:-

prostate:-

ovary:-

testis:-

heart:-

muscle:2.35

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:0

lung:-

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

IDs

Refseq ID	NM_010610
Gene ID	16531
Unigene ID	Mm.458374
Probe set ID	1424848_at [Mouse430_2]
Ensembl ID	ENSMUSG00000063142

Orthologous Gene

Human[8]	NM_001014797, NM_001161352, NM_001161353, NM_002247
Rat [0]

Chromosomal Region

Gene Family (Interpro ID)

IPR003091

Voltage-dependent potassium channel

Gene Ontology (GO ID)

Biological Process

GO:0007628	adult walking behavior
GO:0042491	auditory receptor cell differentiation
GO:0048469	cell maturation
GO:0030007	cellular potassium ion homeostasis
GO:0007623	circadian rhythm
GO:0060082	eye blink reflex
GO:0006811	ion transport
GO:0045475	locomotor rhythm
GO:0060073	micturition
GO:0045794	negative regulation of cell volume
GO:0050885	neuromuscular process controlling balance
GO:0043065	positive regulation of apoptosis
GO:0006813	potassium ion transport
GO:0051260	protein homooligomerization
GO:0051289	protein homotetramerization
GO:0019228	regulation of action potential in neuron
GO:0032344	regulation of aldosterone metabolic process
GO:0034765	regulation of ion transmembrane transport
GO:0042391	regulation of membrane potential
GO:0042312	regulation of vasodilation
GO:0060087	relaxation of vascular smooth muscle
GO:0051592	response to calcium ion
GO:0034465	response to carbon monoxide
GO:0031960	response to corticosteroid stimulus
GO:0043627	response to estrogen stimulus
GO:0001666	response to hypoxia
GO:0006970	response to osmotic stress
GO:0009268	response to pH
GO:0046541	saliva secretion
GO:0007605	sensory perception of sound
GO:0060083	smooth muscle contraction involved in micturition
GO:0007268	synaptic transmission
GO:0055085	transmembrane transport
GO:0006810	transport
GO:0042311	vasodilation

Cellular Component

GO:0016324	apical plasma membrane
GO:0005901	caveola
GO:0043025	cell soma
GO:0005737	cytoplasm
GO:0030425	dendrite
GO:0005783	endoplasmic reticulum
GO:0009897	external side of plasma membrane
GO:0016021	integral to membrane
GO:0016020	membrane
GO:0048471	perinuclear region of cytoplasm
GO:0005886	plasma membrane
GO:0045211	postsynaptic membrane
GO:0048787	presynaptic active zone membrane
GO:0043234	protein complex
GO:0043195	terminal button
GO:0019031	viral envelope
GO:0019012	virion
GO:0008076	voltage-gated potassium channel complex

Molecular Function

GO:0003779	actin binding
GO:0015269	calcium-activated potassium channel activity
GO:0005216	ion channel activity
GO:0060072	large conductance calcium-activated potassium channel activity
GO:0046872	metal ion binding
GO:0005267	potassium channel activity
GO:0005515	protein binding
GO:0032403	protein complex binding
GO:0042803	protein homodimerization activity
GO:0005244	voltage-gated ion channel activity
GO:0005249	voltage-gated potassium channel activity

potassium large conductance calcium-activated channel, subfamily M, alpha member 1

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function